Results 71 to 80 of about 10,990 (185)

An integrated social and natural sciences case study for the reuse of organic wastes as soil amendments

PLANTS, PEOPLE, PLANET, EarlyView.
Reusing organic waste materials, such as animal manure, as soil amendments reduces water and fertiliser demand, contributing to achieving the Sustainable Development Goals. However, organic wastes may contain contaminants of emerging concern (CECs), posing potential ecosystem and human health risks. Despite the importance of this issue, there is a lack
Felicity C. T. Elder, Jose‐Luis Fajardo‐Escoffié, Laura Carter, Emily K. Durant, Katie J. Field, John Nightingale, Brett Sallach, Andrea‐Lorena Garduño‐Jiménez   +7 more
wiley   +1 more source

An Antifungal Combination Matrix Identifies a Rich Pool of Adjuvant Molecules that Enhance Drug Activity against Diverse Fungal Pathogens

Cell Reports, 2015
There is an urgent need to identify new treatments for fungal infections. By combining sub-lethal concentrations of the known antifungals fluconazole, caspofungin, amphotericin B, terbinafine, benomyl, and cyprodinil with ∼3,600 compounds in diverse ...
Nicole Robbins, Michaela Spitzer, Tennison Yu, Robert P. Cerone, Anna K. Averette, Yong-Sun Bahn, Joseph Heitman, Donald C. Sheppard, Mike Tyers, Gerard D. Wright   +9 more
doaj   +1 more source

Candida albicans Genetic Background Influences Mean and Heterogeneity of Drug Responses and Genome Stability during Evolution in Fluconazole

mSphere, 2020
The importance of within-species diversity in determining the evolutionary potential of a population to evolve drug resistance or tolerance is not well understood, including in eukaryotic pathogens.
Aleeza C. Gerstein, Judith Berman
doaj   +1 more source

Candida glabrata : a review of its features and resistance [PDF]

, 2014
Candida species belong to the normal microbiota of the oral cavity and gastrointestinal and vaginal tracts, and are responsible for several clinical manifestations, from mucocutaneous overgrowth to bloodstream infections.
A Chakrabarti, A Chakrabarti, A Kalkanci, A Kramer, A Peñas De Las, A Roetzer, A Roetzer, A Roetzer, A Roetzer, A Thierry, AA Almeida de, AL Colombo, AM Calcagno, AM Nicola, AW Segal, B Dujon, B Guo, B Klempp-Selb, BB Magee, BD Alexander, BP Cormack, C Lass-Flörl, C Marcos-Arias, C. F. Rodrigues, CJ Seneviratne, CS Kaufmann, CS Lim, CT Hittinger, CY Lin, D Dyk van, D Wilson, DA Stead, DC Sheppard, DJ Klionsky, DJ Klionsky, DM Kuhn, DR Reagan, EA Kraneveld, EJ Helmerhorst, EJ Helmerhorst, EK Bethea, EM Kojic, F Bambeke Van, F Barchiesi, F Hasan, FC Odds, FG Oppenheim, FG Oppenheim, G Butler, G Butler, G Luo, G Luo, G Ramage, G Ramage, GM Cox, GR Thompson 3rd, H Muller, H Tsai, H Urk Van, H Wisplinghoff, HM Bandara, HT Taff, I Castaño, I Iraqui, J Chandra, J Chandra, J Kim, J Lee, JA Hagerty, JA Jayatilake, JA Noble, JA Vazquez, JA Vazquez, JCO Sardi, JE Bennett, JH Shin, JL Vincent, JP Vermitsky, JR Blankenship, K Gulshan, K Lewis, K Lewis, K Seider, K Ueno, KE Caudle, KH Chen, KH Wolfe, KJ Verstrepen, KW Henry, L Vale-Silva, LP Samaranayake, LP Samaranayake, M Bassetti, M Edgerton, M Negri, M Niimi, M Niimi, M Riera, M Sikora, M Tscherner, M. Henriques, MA Al-Fattani, MA Pfaller, MA Pfaller, MA Pfaller, MC Arendrup, MC Lorenz, MD LaFleur, MD Lafleur, MN Rai, N Berila, NK Tamura, O Bader, P Gutiérrez-Escribano, P Perumal, P Shahi, P Sundstrom, P Uppuluri, P Vandeputte, P Vandeputte, PL Fidel Jr, PW Groot De, R Domergue, R Kaur, R Kaur, R Kaur, R Rajendran, RA Akins, RA Calderone, RD Cannon, RK Shields, S Brunke, S Brunke, S Farahyar, S Ferrari, S Ferrari, S Hawser, S Paul, S Silva, S Silva, S Silva, S Silva, S Silva, S. Silva, SC Halliwell, SP Hawser, SY Ruan, T Miyazaki, T Saijo, TFC Mah, V Krcmery, V Krcmery, V Mohan das, Y Nakagawa, Z Jandric, Z Xie   +155 more
core   +1 more source

Transforming Treatment: The Impact of Bariatric Surgery on Oral Drug Absorption

Obesity Reviews, EarlyView.
ABSTRACT Obesity represents a significant threat to global public health, with an estimated 16% of adults worldwide (2022) being classified as people with obesity, with a body mass index of 30 or more. Bariatric surgery is regarded as the most effective treatment option for people with obesity, with the three main types of bariatric surgery being ...
Danielle Wigg, Andrea Edginton, Matthew D. Jones, Nikoletta Fotaki   +3 more
wiley   +1 more source

Infections in Chronic Lymphocytic Leukemia: Evolving Risks and Prevention Strategies

European Journal of Haematology, Volume 116, Issue 3, Page 204-214, March 2026.
ABSTRACT Infections remain a leading cause of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL), reflecting both intrinsic immune dysfunction and therapy‐related immunosuppression. The pathogenesis of immunodeficiency in CLL is multifactorial: neoplastic B cells impair humoral immunity, T cells are functionally exhausted, and ...
Enrica Antonia Martino, Santino Caserta, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Fortunato Morabito, Massimo Gentile   +10 more
wiley   +1 more source

Yap1-mediated Flr1 expression reveals crosstalk between oxidative stress signaling and caffeine resistance in Saccharomyces cerevisiae

Frontiers in Microbiology, 2022
Caffeine, a methylxanthine derivative, affects various physiological conditions such as cell growth, proliferation, and energy metabolism. A genome-wide screening for genes required for caffeine resistance in Schizosaccharomyces pombe revealed several ...
Ji Eun Choi, Ji Eun Choi, Seo-Hee Heo, Seo-Hee Heo, Woo-Hyun Chung, Woo-Hyun Chung   +5 more
doaj   +1 more source

Eletriptan in the management of acute migraine. An update on the evidence for efficacy, safety, and consistent response [PDF]

, 2016
Migraine is a multifactorial, neurological and disabling disorder, also characterized by several autonomic symptoms. Triptans, selective serotonin 5-HT1B/1D agonists, are the first-line treatment option for moderate-to-severe headache attacks.
Capi, Matilde, Curto, Martina, De Andrés, Fernando, Gentile, Giovanna, Lionetto, Luana, Martelletti, Paolo, Negro, Andrea   +6 more
core   +1 more source

Repurposing drugs to fast-track therapeutic agents for the treatment of cryptococcosis [PDF]

, 2018
Many infectious diseases disproportionately affect people in the developing world. Cryptococcal meningitis is one of the most common mycoses in HIV-AIDS patients, with the highest burden of disease in sub-Saharan Africa.
Afeltra, Bicanic, Butts, Byrnes, Catterall, Ceballos, Chatterji, Chong, Chrysant, Clinical and Laboratory Standards Institute (CLSI), Clinical and Laboratory Standards Institute (CLSI), Cruz, Cruz, Cumino, Dehdashti, Del Poeta, Dzoyem, Edlind, Espinel-Ingroff, Feldmeier, Gaggi, Hagen, Hong, Hong, Horton, Jarvis, Joffe, Kneale, Lai, Lassègue, Liu, Liu, Loyse, Meiring, Nixon, Oprea, Park, Peiter, Perfect, Prole, Rabjohns, Rajasingham, Rhein, Samantaray, Smith, Spagnuolo, Spitzer, Teng, Téllez-Girón, Zhai, Zhai   +50 more
core   +3 more sources

Characterization, Antimicrobial, and Antiproliferative Activities of Silver Nanoparticles Biosynthesized Using Terminalia phanerophlebia Engl. & Diels

Cell Biochemistry and Function, Volume 44, Issue 2, February 2026.
ABSTRACT The application of nanoparticles (NPs) as therapeutic strategies for treating microbial infections and cancer is gaining attention due to their physicochemical properties. In this study, we synthesized silver nanoparticles (AgNPs) from the aqueous extract of the roots and leaves of Terminalia phanerophlebia.
Folasade O. Banji‐Onisile, Nneka A. Akwu, Tosin A. Olasehinde, Ademola O. Olaniran   +3 more
wiley   +1 more source