Pharmacodynamic and pharmacokinetic effects of flumazenil and theophylline application in rats acutely intoxicated by diazepam [PDF]
Background/Aim. The majority of symptoms and signs of acute diazepam poisoning are the consequence of its sedative effect on the CNS affecting selectively polisynaptic routes by stimulating inhibitory action of GABA.
Šegrt Zoran+7 more
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Flumazenil may improve gait and mentation in dogs presenting with marijuana toxicosis [PDF]
IntroductionAlongside the United States’ growing landscape of legalized recreational marijuana intended for humans, cases of canine marijuana toxicosis have been on the rise.
Alyson H. Fitzgerald+6 more
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Flumazenil-induced Ballism [PDF]
Flumazenil, an imidazobenzodiazepine, is the first benzodiazepine antagonist and is being used to reverse the adverse pharmacological effects of benzodiazepine. There have been a few reports on the central nevous system side effects with its use. We report a patient with generalized ballism following administration of flumazenil.
Joong‐Seok Kim+3 more
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Continuous Infusion of Flumazenil in the Management of Benzodiazepines Detoxification [PDF]
An effective approach in the treatment of benzodiazepine (BZD) overdosing and detoxification is flumazenil (FLU). Studies in chronic users who discontinued BZD in a clinical setting suggested that multiple slow bolus infusions of FLU reduce BZD ...
Anna Benini+5 more
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[11C]flumazenil binding is increased in a dose-dependent manner with tiagabine-induced elevations in GABA levels. [PDF]
Evidence indicates that synchronization of cortical activity at gamma-band frequencies, mediated through GABA-A receptors, is important for perceptual/cognitive processes.
W Gordon Frankle+8 more
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Facilitation of cholinergic transmission by combined treatment of ondansetron with flumazenil after cortical cholinergic deafferentation [PDF]
We have studied the effects of concomitant blockade of 5-HT(3) and GABA(A) receptors on acetylcholine (ACh) release in the frontal cortex of rats with a selective cholinergic lesion.
Dominguez, J. (Jon)+5 more
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Flumazenil Binding and Cortical Malformations [PDF]
Central Benzodiazepine Receptors in Malformations of Cortical Development: A Quantitative Study Hammers A, Koepp MJ, Richardson MP, Labbe C, Brooks DJ, Cunningham VJ, Duncan J Brain 2001;124:1555–1565 Purpose We calculated [11C]flumazenil volume of distribution ([11C]FMZ-Vd] after correction for partial volume effect in 10 patients with ...
William H. Theodore
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Remimazolam-flumazenil provides fast recovery from general anesthesia compared to propofol during radiofrequency catheter ablation of atrial fibrillation [PDF]
The optimal anesthetic agent for radiofrequency catheter ablation (RFCA) of atrial fibrillation (AF) and its impact on the recovery profiles remain uncertain.
Seohee Lee+9 more
doaj +2 more sources
Case report of atypical re-sedation after general anesthesia using remimazolam [PDF]
Background Remimazolam, an ultra-short-acting anesthetic with flumazenil as a reversal agent, typically facilitates patient awakening postoperatively. However, our case reveals an unusual occurrence: despite flumazenil initially restoring consciousness ...
Soo Jee Lee+3 more
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Clinical Study of Flumazenil Antagonizing Remimazolam on Nausea and Vomiting After Gynecologic Day Surgery [Letter] [PDF]
Muhammed Halit Satici,1 Nuray Altay2 1University of Health Sciences, Konya City Hospital Department of Anesthesiology and Reanimation, Konya, Turkey; 2Harran University, Faculty of Medicine, Department of Anesthesiology and Reanimation, Şanl ...
Satici MH, Altay N
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