Results 21 to 30 of about 14,172 (248)

Flumazenil and Hypoxic Ventilatory Response

Anesthesia & Analgesia, 1990
Christina T. Mora, Marc C. Torjman, Paul F. White   +2 more
openalex   +4 more sources

A NEW APPROACH IN TREATMENT ACUTE IVERMECTIN TOXICITY IN MALE BALB-C MICE

The Iraqi Journal of Agricultural science, 2021
This study was conducted to investigate the potential therapeutic of flumazenil and neostigmine in single and combination in Balb-C mice subjected to ivermectin acute oral toxicity.
F. M. K . Al-Rekabi, A. Alsadawi, Ali. I. Al-ameedi   +2 more
doaj   +1 more source

Flumazenil in benzodiazepine overdose [PDF]

Canadian Medical Association Journal, 2016
A population-based retrospective study reported a rate of 3.0–7.9 deaths per million benzodiazepine prescriptions.[1][1] Sedation is common, but severe respiratory depression and hemodynamic instability are rare.[2][2] Supportive care is generally sufficient for the management of ...
Jesse Godwin, Howard An
openaire   +3 more sources

Automated Synthesis of [¹⁸F]Flumazenil Application in GABA_A Receptor Neuroimaging Availability for Rat Model of Anxiety

Pharmaceuticals, 2023
Clinical studies have demonstrated that the γ-aminobutyric acid type A (GABAA) receptor complex plays a central role in the modulation of anxiety.
Shiou-Shiow Farn, Kai-Hung Cheng, Yuan-Ruei Huang, Shih-Ying Lee, Jenn-Tzong Chen, Kang-Wei Chang   +5 more
doaj   +1 more source

Flumazenil-Insensitive Benzodiazepine Effects in Recombinant αβ and Neuronal GABA_A Receptors

Brain Sciences, 2020
Gamma-aminobutyric acid, type A (GABAA) receptors are complex heterogeneous pentamers with various drug binding sites. Several lines of evidence suggest that benzodiazepines modulate certain GABAA receptors in a flumazenil-insensitive manner, possibly ...
Jing-Jing Lian, Yan-Qing Cao, Yu-Lei Li, Gang Yu, Rui-Bin Su   +4 more
doaj   +1 more source

Efficacy and safety of remimazolam tosilate versus propofol in patients undergoing day surgery: a prospective randomized controlled trial

BMC Anesthesiology, 2023
Background Remimazolam tosilate (RT) is a novel short-acting GABA (A) receptor agonist that has a rapid recovery from procedural sedation and can be fully reversed by flumazenil.
Wenchen Luo, Minli Sun, Jie Wan, Zhenyu Zhang, Jian Huang, Jinlin Zhang, Wanxia Xiong, Lirong Xia, Peiyao Xu, Changhong Miao, Xuesong Zhang, Mingyue Liu, Jing Zhong   +12 more
doaj   +1 more source

Re-audit of the use of flumazenil following midazolam-induced conscious sedation

BDJ Open, 2023
Introduction Flumazenil is an antagonist drug of Benzodiazepam (BDZ) that has been used as a reversal agent of midazolam-induced conscious sedation (CS) in both emergency and elective procedures.
Muhammad Syafiq Asyraf Rosli, Ellie Heidari   +1 more
doaj   +1 more source

GABAA receptor availability relates to emotion-induced BOLD responses in the medial prefrontal cortex: simultaneous fMRI/PET with [11C]flumazenil

Frontiers in Neuroscience, 2023
IntroductionThe fMRI BOLD response to emotional stimuli highlighting the role of the medial prefrontal cortex (MPFC) has been thoroughly investigated.
Alexander Heinzel, Alexander Heinzel, Alexander Heinzel, Jörg Mauler, Hans Herzog, Frank Boers, Felix M. Mottaghy, Felix M. Mottaghy, Karl-Josef Langen, Karl-Josef Langen, Jürgen Scheins, Christoph Lerche, Bernd Neumaier, Georg Northoff, N. Jon Shah, N. Jon Shah, N. Jon Shah, N. Jon Shah   +17 more
doaj   +1 more source

Ro 15-4513 Antagonizes Alcohol-Induced Sedation in Mice Through aß¿2-type GABA(A) Receptors [PDF]

, 2011
Peer reviewedPublisher ...
Korpi, Esa R, Leppä, Elli, Linden, Anni-Maija, Lüddens, Hartmut, Schmitt, Ulrich, Wisden, William, Wulff, Peer   +6 more
core   +3 more sources

Flumazenil does not improve hepatic encephalopathy associated with acute ischemic liver failure in the rabbit [PDF]

, 1990
The effect of flumazenil, a benzodiazepine antagonist, on hepatic encephalopathy was studied in rabbits with acute hepatic failure induced by a two-stage liver devascularization procedure.
Knegt, R.J. (Robert) de, Mechelse, K. (Karel), Rijt, C.C.D. (Carin) van der, Schalm, S.W. (Solko), Terpstra, O.T. (Onno)   +4 more
core   +1 more source