Results 91 to 100 of about 19,247 (245)

Efficacy of an adenovirus-vectored foot-and-mouth disease virus serotype A subunit vaccine in cattle using a direct contact transmission model

BMC Veterinary Research, 2018
Background A direct contact transmission challenge model was used to simulate natural foot-and-mouth disease virus (FMDV) spread from FMDV A24/Cruzeiro/BRA/55 infected ‘seeder’ steers to naïve or vaccinated steers previously immunized with a replication ...
John G. Neilan, Christopher Schutta, José Barrera, Melia Pisano, Laszlo Zsak, Ethan Hartwig, Max V. Rasmussen, Barbara J. Kamicker, Damodar Ettyreddy, Douglas E. Brough, Bryan T. Butman, David A. Brake   +11 more
doaj   +1 more source

Japanese Encephalitis Virus Genotype 5 Infectious Clone and Reporter System for Antiviral Evaluation

Journal of Medical Virology, Volume 97, Issue 9, September 2025.
ABSTRACT The recent emergence of Japanese encephalitis virus genotype 5 (JEV5) has raised concerns regarding limited vaccine efficacy. Here, we report the construction of a full‐length infectious cDNA clone of JEV5 using a bacterial artificial chromosome (BAC) system, based on a South Korea isolate, K15P38 strain.
Jae‐Yeon Park, Wataru Kamitani, Hyun‐Jin Shin, Hye‐Mi Lee   +3 more
wiley   +1 more source

Advances in Foot-and-Mouth Disease Virus Proteins Regulating Host Innate Immunity

Frontiers in Microbiology, 2020
Foot-and-mouth disease (FMD) is a highly contagious disease that affects cloven-hoofed animals such as pigs, cattle, and sheep. The disease is caused by the foot-and-mouth disease virus (FMDV) which has a non-enveloped virion with icosahedral symmetry ...
Jiangling Peng, Jiamin Yi, Wenping Yang, Jingjing Ren, Yuan Wen, Haixue Zheng, Dan Li   +6 more
doaj   +1 more source

Foot-and-mouth disease virus VP1 promotes viral replication by regulating the expression of chemokines and GBP1

Frontiers in Veterinary Science, 2022
Foot-and-mouth disease virus (FMDV) is an acute, highly contagious, and economically destructive pathogen of vesicular disease that affects domestic and wild cloven-hoofed animals. The FMDV VP1 protein is an important part of the nucleocapsid and plays a
Li Yang, Li Yang, Li Yang, Hong Chen, Hong Chen, Hong Chen, Liqing Liu, Liqing Liu, Liqing Liu, Jingjing Song, Jingjing Song, Jingjing Song, Tian Feng, Tian Feng, Tian Feng, Yihan Li, Yihan Li, Yihan Li, Chao Shen, Lingbao Kong, Lingbao Kong, Lingbao Kong, Xiu Xin, Xiu Xin, Xiu Xin   +24 more
doaj   +1 more source

Development of a Conventional Reverse Transcription‐PCR System for Broad Detection of Bovine Rhinitis A Virus

Veterinary Medicine and Science, Volume 11, Issue 5, September 2025.
Amplified genome using RT‐PCR with the new primer pair. ABSTRACT Bovine rhinitis A virus (BRAV) is a virus of the genus Aphthovirus, family Picornaviridae. BRAV has recently attracted interest as a causative agent in bovine respiratory disease complex (BRDC).
Shunjiro Koizumi, Tatsuya Nishi, Kazuki Morioka, Katsuhiko Fukai   +3 more
wiley   +1 more source

Plant-produced viral bovine vaccines: What happened during the last ten years? [PDF]

, 2015
Vaccination has proved to be an efficient strategy to deal with viral infections in both human and animal species. However, protection of cattle against viral infections is still a major concern in veterinary science.
Dus Santos, María José, Mozgovoj, Marina Valeria, Ruiz, Vanesa, Wigdorovitz, Andrés   +3 more
core   +1 more source

Development of gold nanoparticles biosensor for ultrasensitive diagnosis of foot and mouth disease virus

Journal of Nanobiotechnology, 2018
Background Nano-PCR is a recent tool that is used in viral diseases diagnosis. The technique depends on the fundamental effects of gold nanoparticles (AuNPs) and is considered a very effective and sensitive tool in the diagnosis of different diseases ...
Mervat E. Hamdy, Michele Del Carlo, Hussein A. Hussein, Taher A. Salah, Ayman H. El-Deeb, Mohamed M. Emara, Guilia Pezzoni, Dario Compagnone   +7 more
doaj   +1 more source

Heat Shock Protein 60 Is Involved in Viral Replication Complex Formation and Facilitates Foot and Mouth Virus Replication by Stabilizing Viral Nonstructural Proteins 3A and 2C

mBio, 2022
The maintenance of viral protein homeostasis depends on the machinery of the infected host cells, giving us an insight into the interplay between host and virus.
Jianli Tang, Sahibzada Waheed Abdullah, Pinghua Li, Jin'en Wu, Chenchen Pei, Suyu Mu, Yunlu Wang, Shiqi Sun, Huichen Guo   +8 more
doaj   +1 more source

Australia versus Denmark: an analysis of foot‐and‐mouth disease mitigation strategies

Australian Veterinary Journal, Volume 103, Issue 9, Page 571-581, September 2025.
Foot‐and‐mouth disease (FMD) has progressively increased as an economically significant viral pathogen to the global agricultural and livestock industries, especially in those countries listed as FMD‐free, such as Australia and Denmark. The potential risk associated with the loss of this status enlists an equally significant level of biosecurity and ...
AJB Wagner, AE Boklund, MP Ward
wiley   +1 more source

Development of Foot-and-Mouth Disease Virus-Neutralizing Monoclonal Antibodies Derived From Plasmablasts of Infected Cattle and Their Germline Gene Usage

Frontiers in Immunology, 2019
Cattle are susceptible to foot-and-mouth disease virus (FMDV), and neutralizing antibodies are critical for protection against FMDV infection in this species.
Kun Li, Sheng Wang, Yimei Cao, Huifang Bao, Pinghua Li, Pu Sun, Xingwen Bai, Yuanfang Fu, Xueqing Ma, Jing Zhang, Dong Li, Yingli Chen, Xuerong Liu, Fanglan An, Faju Wu, Zengjun Lu, Zaixin Liu   +16 more
doaj   +1 more source