Results 41 to 50 of about 7,938 (206)

The High Immunity Induced by the Virus-Like Particles of Foot-and-Mouth Disease Virus Serotype O

Frontiers in Veterinary Science, 2021
Foot-and-mouth disease (FMD), caused by FMD virus (FMDV), is a highly contagious and economically devastating viral disease of cloven-hoofed animals worldwide.
Yan Xiao, Yan Xiao, Suling Zhang, He Yan, Xiaolin Geng, Yanwei Wang, Xin Xu, Mengyue Wang, Haohao Zhang, Baicheng Huang, Wenqiang Pang, Ming Yang, Kegong Tian, Kegong Tian   +13 more
doaj   +1 more source

Peptides Interfering 3A Protein Dimerization Decrease FMDV Multiplication

PLOS ONE, 2015
Nonstructural protein 3A is involved in relevant functions in foot-and-mouth disease virus (FMDV) replication. FMDV 3A can form homodimers and preservation of the two hydrophobic α-helices (α1 and α2) that stabilize the dimer interface is essential for virus replication.
González Magaldi, Mónica, Vázquez Calvo, Ángela, Torre, Beatriz G. de la, Valle, Javier, Andreu Martínez, David, Sobrino, Francisco   +5 more
openaire   +6 more sources

The Application of the Gibson Assembly Method in the Production of Two pKLS3 Vector-Derived Infectious Clones of Foot-and-Mouth Disease Virus

Vaccines, 2023
The construction of a full-length infectious clone, essential for molecular virological study and vaccine development, is quite a challenge for viruses with long genomes or possessing complex nucleotide sequence structures.
Ploypailin Semkum, Nattarat Thangthamniyom, Penpitcha Chankeeree, Challika Keawborisuth, Sirin Theerawatanasirikul, Porntippa Lekcharoensuk   +5 more
doaj   +1 more source

Sec62 Regulates Endoplasmic Reticulum Stress and Autophagy Balance to Affect Foot-and-Mouth Disease Virus Replication

Frontiers in Cellular and Infection Microbiology, 2021
Endoplasmic reticulum (ER) stress-induced autophagy is closely associated with viral infection and propagation. However, the intrinsic link between ER stress, autophagy, and viral replication during foot-and-mouth disease virus (FMDV) infection is not ...
Jin’en Wu, Zhihui Zhang, Zhidong Teng, Sahibzada Waheed Abdullah, Shiqi Sun, Huichen Guo, Huichen Guo   +6 more
doaj   +1 more source

Foot-and-Mouth Disease Virus 3C Protease Antagonizes Interferon Signaling and C142T Substitution Attenuates the FMD Virus

Frontiers in Microbiology, 2021
3C protease (3Cpro), a chymotrypsin-like cysteine protease encoded by the foot-and-mouth disease virus (FMDV), plays an essential role in processing the FMDV P1 polyprotein into individual viral capsid proteins in FMDV replication.
Pathum Ekanayaka, Sung Ho Shin, Prasanna Weeratunga, Hyuncheol Lee, Hyuncheol Lee, Tae-Hwan Kim, Tae-Hwan Kim, Kiramage Chathuranga, Ashan Subasinghe, Jong-Hyeon Park, Jong-Soo Lee   +10 more
doaj   +1 more source

FMDV RNA packaging and capsid assembly

, 2021
Foot-and-mouth disease virus (FMDV), of the Picornaviridae family, is a non-enveloped, single-stranded, positive-sense RNA virus. FMDV infects cloven-hooved animals and is an important pathogen for global agriculture due to the economic consequences of both endemic disease and epidemic outbreaks.
openaire   +2 more sources

FMDV Leader Protein Interacts with the NACHT and LRR Domains of NLRP3 to Promote IL-1β Production

Viruses, 2021
Foot-and-mouth disease virus (FMDV) infection causes inflammatory clinical symptoms, such as high fever and vesicular lesions, even death of animals.
Sk Mohiuddin Choudhury, Xusheng Ma, Yuanyuan Li, Xiaofeng Nian, Zhikuan Luo, Yonghua Ma, Zixiang Zhu, Fan Yang, Weijun Cao, Haixue Zheng   +9 more
doaj   +1 more source

A gold nanoparticle strip for simultaneously evaluating FMDV immunized antibody level and discriminating FMDV vaccinated animals from infected animals

RSC Advances, 2019
A gold nanoparticle strip was developed for rapidly evaluating FMDV type O antibody level and simultaneously discriminating FMDV vaccinated animals from infected animals.
Suzhen Yang, Yaning Sun, Jifei Yang, Yunchao Liu, Hua Feng, Gaiping Zhang   +5 more
openaire   +3 more sources

The pH stability of foot-and-mouth disease virus

Virology Journal, 2017
ᅟ This review summarized the molecular determinants of the acid stability of FMDV in order to explore the uncoating mechanism of FMDV and improve the acid stability of vaccines.
Hong Yuan, Pinghua Li, Xueqing Ma, Zengjun Lu, Pu Sun, Xingwen Bai, Jing Zhang, Huifang Bao, Yimei Cao, Dong Li, Yuanfang Fu, Yingli Chen, Qifeng Bai, Jie Zhang, Zaixin Liu   +14 more
doaj   +1 more source

Sensitivity of specimen type for diagnosing foot-and-mouth diseases in cattle using one-step real-time polymerase chain reaction (3D gene)

Open Veterinary Journal
Background: Indonesia is currently experiencing a foot and mouth disease (FMD) outbreak in livestock, caused by the foot and mouth disease virus. FMDV is easily spread to cause outbreaks in new geographical locations. Identifying Foot and mouth diseases
Siswani Siswani, Mochammad Hatta, Muflihanah Muflihanah, Nurul Muslinah Muhiddin, Fitrine Ekawasti, Rini Damayanti, Riza Zainuddin Ahmad, Putri Reno Intan, Fitriana Fitriana, Muhammad Ibrahim Desem, Ratih Rinendyaputri   +10 more
doaj   +1 more source