Results 41 to 50 of about 19,247 (245)

Tolerance to mutations in the foot-and-mouth disease virus integrin-binding RGD region is different in cultured cells and in vivo and depends on the capsid sequence context. [PDF]

, 2008
Engineered RNAs carrying substitutions in the integrin receptor-binding Arg-Gly-Asp (RGD) region of foot-and-mouth disease virus (FMDV) were constructed (aa 141-147 of VP1 capsid protein) and their infectivity was assayed in cultured cells and suckling
Baranowski, Eric, Gutiérrez-Rivas, Monica, Pulido, Miguel R, Sobrino, Francisco, Sáiz, Margarita   +4 more
core   +3 more sources

Development and characterisation of a fully recombinant competition ELISA for the diagnosis of foot-and-mouth disease virus infection. [PDF]

Aust Vet J
Infection of livestock by foot‐and‐mouth disease (FMD) virus (FMDV) has serious economic implications due to productivity losses and trade restrictions. In countries that are free from foot and mouth disease, the World Organisation for Animal Health (WOAH) provides two proof of freedom from disease status categories; namely, FMD‐free without using ...
Ye S, Balasubramanian NS, Dolezal O, Foord A, Beddome G, Michalski WP, Shiell BJ, Peck GR.   +7 more
europepmc   +2 more sources

A qualitative risk assessment of factors contributing to foot and mouth disease outbreaks in cattle along the western boundary of the Kruger National Park [PDF]

, 2009
Between November 2000 and the end of 2007, five outbreaks of foot and mouth disease (FMD) occurred in cattle in the area adjacent to the Kruger National Park (KNP) in the north-eastern corner of South Africa.
Bengis, R.G., Brahmbhatt, Dipa P., Du Plessis, B., Gummow, Bruce, Jori, Ferran, Thomson, G.R., Vosloo, Wilna   +6 more
core   +1 more source

Evolution of foot-and-mouth disease virus intra-sample sequence diversity during serial transmission in bovine hosts [PDF]

, 2013
RNA virus populations within samples are highly heterogeneous, containing a large number of minority sequence variants which can potentially be transmitted to other susceptible hosts. Consequently, consensus genome sequences provide an incomplete picture
Haydon, D.T., Juleff, N., King, D.P., Knowles, N.J., Morelli, M.J., Paton, D.J., Wright, C.F.   +6 more
core   +2 more sources

Foot-and-Mouth Disease Virus Counteracts on Internal Ribosome Entry Site Suppression by G3BP1 and Inhibits G3BP1-Mediated Stress Granule Assembly via Post-Translational Mechanisms

Frontiers in Immunology, 2018
Foot-and-mouth disease (FMD) is a highly contagious, severe viral illness notifiable to the World Organization for Animal Health. The causative agent, FMD virus (FMDV), replicates rapidly and efficiently inhibits host translation and the innate immune ...
Xu Ye, Xu Ye, Ting Pan, Ting Pan, Dang Wang, Dang Wang, Liurong Fang, Liurong Fang, Jun Ma, Jun Ma, Xinyu Zhu, Xinyu Zhu, Yanling Shi, Yanling Shi, Keshan Zhang, Haixue Zheng, Huanchun Chen, Huanchun Chen, Kui Li, Shaobo Xiao, Shaobo Xiao   +20 more
doaj   +1 more source

A serological survey of ruminant livestock in Kazakhstan during post-Soviet transitions in farming and disease control [PDF]

, 2004
The results of a serological survey of livestock in Kazakhstan, carried out in 1997–1998, are reported. Serum samples from 958 animals (cattle, sheep and goats) were tested for antibodies to foot and mouth disease (FMD), bluetongue (BT), epizootic ...
Corteyn, A., Hamblin , C., Lundervold, M., Macmillan, A.P., Milner-Gulland, E. J., O'Callaghan, C. J.   +5 more
core   +4 more sources

The Carrier Conundrum; A Review of Recent Advances and Persistent Gaps Regarding the Carrier State of Foot-and-Mouth Disease Virus

Pathogens, 2020
The existence of a prolonged, subclinical phase of foot-and-mouth disease virus (FMDV) infection in cattle was first recognized in the 1950s. Since then, the FMDV carrier state has been a subject of controversy amongst scientists and policymakers.
Carolina Stenfeldt, Jonathan Arzt
doaj   +1 more source

The Application of the Gibson Assembly Method in the Production of Two pKLS3 Vector-Derived Infectious Clones of Foot-and-Mouth Disease Virus

Vaccines, 2023
The construction of a full-length infectious clone, essential for molecular virological study and vaccine development, is quite a challenge for viruses with long genomes or possessing complex nucleotide sequence structures.
Ploypailin Semkum, Nattarat Thangthamniyom, Penpitcha Chankeeree, Challika Keawborisuth, Sirin Theerawatanasirikul, Porntippa Lekcharoensuk   +5 more
doaj   +1 more source

Distinguishing low frequency mutations from RT-PCR and sequence errors in viral deep sequencing data [PDF]

, 2015
There is a high prevalence of coronary artery disease (CAD) in patients with left bundle branch block (LBBB); however there are many other causes for this electrocardiographic abnormality.
Haydon, Daniel T., King, David J., King, Donald, Morelli, Marco J., Orton, Richard J., Paton, David, Wright, Caroline F.   +6 more
core   +2 more sources

Complete genome sequences of three African foot-and-mouth disease viruses from clinical samples isolated in 2009 and 2010 [PDF]

, 2016
<p>The complete genome sequences of three foot-and-mouth disease viruses (one virus of each serotype SAT1, SAT2 and O) were directly sequenced from RNA extracted from clinical bovine samples, demonstrating the feasibility of full-genome sequencing ...
De Clercq, Kris, Fana, Mpolokang Elliot, Haegeman, Andy, Hyera, Joseph, Matlho, George, Rosseel, Toon, Seoke, Latoa, Van Borm, Steven, Vandenbussche, Frank   +8 more
core   +1 more source