Results 111 to 120 of about 64,048 (160)

EphB Maintains Dendritic Spine Morphology through Focal Adhesion Kinase: Figure 1. [PDF]

The Journal of Neuroscience, 2009
Yu Chen, Wing-Yu Fu
openaire   +1 more source

Adenylyl Cyclase Type 8 Overexpression Impairs Phosphorylation-Dependent Orai1 Inactivation and Promotes Migration in MDA-MB-231 Breast Cancer Cells. [PDF]

, 2019
Orai1 plays a major role in store-operated Ca 2+ entry (SOCE) in triple-negative breast cancer (TNBC) cells. This channel is inactivated via different mechanisms, including protein kinase C (PKC) and protein kinase A (PKA)-dependent phosphorylation at ...
Falcón Boyano, Débora, Smani Hajami, Tarik   +1 more
core  

Loss of synchronized retinal phagocytosis and age-related blindness in mice lacking alphavbeta5 integrin. [PDF]

, 2004
Daily phagocytosis by the retinal pigment epithelium (RPE) of spent photoreceptor outer segment fragments is critical for vision. In the retina, early morning circadian photoreceptor rod shedding precedes synchronized uptake of shed photoreceptor ...
Brodie, Scott E, Finnemann, Silvia C, Huang, Xiaozhu, Kim, Yoonhee, Nandrot, Emeline F, Sheppard, Dean   +5 more
core   +1 more source

Nanoscale TiO2 nanotubes govern the biological behavior of human glioma and osteosarcoma cells

International Journal of Nanomedicine, 2015
Ang Tian,1 Xiaofei Qin,2 Anhua Wu,2 Hangzhou Zhang,3 Quan Xu,4 Deguang Xing,2 He Yang,1 Bo Qiu,2 Xiangxin Xue,1 Dongyong Zhang,2 Chenbo Dong5 1Liaoning Provincial Universities Key Laboratory of Boron Resource Ecological ...
Tian A, Qin XF, Wu A, Zhang H, Xu Q, Xing D, Yang H, Qiu B, Xue X, Zhang D, Dong C   +10 more
doaj  

Focal adhesion kinase promotes aerobic glycolysis in hepatic stellate cells via the cyclin D1/c-Myc/MCT-1 pathway to induce liver fibrosis

Scientific Reports
Hepatic stellate cells (HSCs) transdifferentiate into myofibroblasts during liver fibrosis and exhibit increased glycolysis. Phosphorylated focal adhesion kinase (FAK) (pY397-FAK) promotes monocarboxylate transporter 1 (MCT-1) expression in HSCs to ...
Tao Huang, Ming-Yu Zhou, Gao-Liang Zou, Rui-Han Hu, Lu Han, Qing-Xiu Zhang, Xue-Ke Zhao   +6 more
doaj   +1 more source

Protective effect and mechanism of citrulline on intestinal injury induced by radiation in mice

He jishu
BackgroundIonizing radiation can cause damage to animal's intestinal tissue. Citrulline is produced in the intestinal epithelial cell and has been proven to possess a protective effect on the gastrointestinal tract.PurposeThis study aims to investigate ...
FENG Jundong, LIU Liang, LIU Wenqian, LI Qian, TIAN Liuxin, HE Chengyu, BO Hongyu, WANG Weitai, YANG Yingqing   +8 more
doaj   +1 more source

The COOH terminus of the c-Abl tyrosine kinase contains distinct F- and G-actin binding domains with bundling activity [PDF]

, 1994
The myristoylated form of c-Abl protein, as well as the P210bcr/abl protein, have been shown by indirect immunofluorescence to associate with F-actin stress fibers in fibroblasts. Analysis of deletion mutants of c-Abl stably expressed in fibroblasts maps
Baltimore, David, Jackson, Peter K., Janmey, Paul A., Matsudaira, Paul T., Sanders, Mitchell C., Van Etten, Richard A.   +5 more
core   +4 more sources

Focal Adhesion Kinase 1 [PDF]

, 2020
openaire   +1 more source

Purification of Cortactin Using Anion Exchange Chromatography [PDF]

, 2014
Cortactin is an actin-binding protein that has been shown to be involved in cellular migration and metastases in cancer. Bacterially expressed and purified cortactin protein is often used in in vitro assays to examine cortactin’s role in promoting cell ...
Priester, Jacob
core   +1 more source

Redox regulation of focal adhesions

Redox Biology
Focal adhesions (FAs), multi-protein complexes that link the extracellular matrix to the intracellular cytoskeleton, are key mediators of cell adhesion, migration, and proliferation.
Gianmarco Matrullo, Giuseppe Filomeni, Salvatore Rizza   +2 more
doaj   +1 more source