Results 41 to 50 of about 27,806 (222)

Non-ischemic cardiomyopathy with focal segmental glomerulosclerosis

Journal of Community Hospital Internal Medicine Perspectives, 2020
Focal segmental glomerulosclerosis (FSGS) is a common cause of nephrotic syndrome, accounting for 40% of nephrotic syndrome in adults. FSGS has diverse clinical and morphological features and underlying pathogenesis.
Parminder Kaur, Balraj Singh, Prem Patel, Rahul Vasudev, Upamanyu Rampal, Fayez Shamoon   +5 more
doaj   +1 more source

Focal segmental glomerulosclerosis: Molecular genetics and targeted therapies [PDF]

, 2015
Recent advances show that human focal segmental glomerulosclerosis (FSGS) is a primary podocytopathy caused by podocyte-specific gene mutations including NPHS1, NPHS2, WT-1, LAMB2, CD2AP, TRPC6, ACTN4 and INF2.
Chen, Ying Maggie, Liapis, Helen
core   +2 more sources

5‐Methylcytosine Analysis of miRNAs in Minimal Change Disease

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Minimal change disease (MCD) is a glomerular disorder, which is the most common cause of nephrotic syndrome in children. Additionally, the prevalence of MCD in adults has been increasing in recent years. During protein synthesis, noncoding RNAs can be regulated through a variety of modifications, which helps preserve biological diversity and ...
Huiyi Zeng, Dandan Li, Yunyi Li, Chen Yun, Xinzhou Zhang, Wenyu Gong, Mengyun Xiao, Haitao Li, Zhipeng Zeng, Ruqi Tan, Yishen Yang, Shaodong Luan, Yong Dai, Lianghong Yin, Donge Tang   +14 more
wiley   +1 more source

Collapsing Focal Segmental Glomerulosclerosis in Viral Infections

Frontiers in Immunology, 2022
Collapsing glomerulopathy represents a special variant of the proteinuric kidney disease focal segmental glomerulosclerosis (FSGS). Histologically, the collapsing form of FSGS (cFSGS) is characterized by segmental or global condensation and obliteration ...
Anne K. Muehlig, Anne K. Muehlig, Anne K. Muehlig, Sydney Gies, Tobias B. Huber, Fabian Braun   +5 more
doaj   +1 more source

Genetics of focal segmental glomerulosclerosis [PDF]

Pediatric Nephrology, 2007
AbstractThe recent advances in understanding the pathophysiology of focal segmental glomerulosclerosis (FSGS) and molecular function of glomerular filtration barrier come directly from genetic linkage and positional cloning studies. The exact role and function of the newly discovered genes and proteins are being investigated by in vitro and in vivo ...
Woroniecki, Robert P., Kopp, Jeffrey B.
openaire   +2 more sources

Biological Pathways and Potential Targets for Prevention and Therapy of Chronic Allograft Nephropathy [PDF]

, 2014
Renal transplantation (RT) is the best option for patients with end-stage renal disease, but the half-life is limited to a decade due to progressive deterioration of renal function and transplant failure from chronic allograft nephropathy (CAN), which is
Haylor, John, Shrestha, Badri Man
core   +3 more sources

Immune-complex glomerulonephritis with a membranoproliferative pattern in Frasier syndrome: a case report and review of the literature

BMC Nephrology, 2020
Background Mutations in the Wilms tumor 1 gene cause a spectrum of podocytopathy ranging from diffuse mesangial sclerosis to focal segmental glomerulosclerosis.
Daisuke Matsuoka, Shunsuke Noda, Motoko Kamiya, Yoshihiko Hidaka, Hisashi Shimojo, Yasushi Yamada, Tsutomu Miyamoto, Kandai Nozu, Kazumoto Iijima, Hiroyasu Tsukaguchi   +9 more
doaj   +1 more source

HIV-related nephropathy: A South African perspective [PDF]

, 2005
Human immunodeficiency virus (HIV)-associated nephropathy (HIVAN) is an important cause of renal failure in those of African origin. A number of other kidney diseases occur in HIV-positive patients.
Gerntholtz, T.E., Goetsch, S.J.W., Katz, I.   +2 more
core   +1 more source

Interpretative Phenomenological Study Exploring Why People With Kidney Failure Say ‘No’ to a Kidney Transplant

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To develop an in‐depth understanding of peoples' perceptions and experiences of decision‐making and reasons why they declined the opportunity of a kidney transplant. Design The Theory of Planned Behaviour informed the qualitative interpretative phenomenological analysis. Methods Semi‐structured interviews were conducted between August 2022
Emma Jones, Leah McLaughlin, Kate Shakespeare, Jane Noyes   +3 more
wiley   +1 more source

Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]

, 2000
The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim, Schlöndorff, Detlef   +1 more
core   +1 more source