Results 51 to 60 of about 457,931 (292)
Animal, 2013 Folate transporters, including the reduced folate carrier and the proton-coupled folate transporter, encoded by Slc19a1 and Slc46a1 genes respectively, play important roles in the transport of folate across biological membranes given the hydrophilic ...
M. Jing, G.B. Tactacan, J.D. House
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Membrane mediated toppling mechanism of the folate energy coupling factor transporter
Nature Communications, 2020 Energy coupling factor (ECF) transporters are responsible for the uptake of micronutrients and consist of an integral membrane unit, the S-component, which confers substrate specificity.
Ignacio Faustino +7 more
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Glycine and Folate Ameliorate Models of Congenital Sideroblastic Anemia. [PDF]
PLoS Genetics, 2016 Sideroblastic anemias are acquired or inherited anemias that result in a decreased ability to synthesize hemoglobin in red blood cells and result in the presence of iron deposits in the mitochondria of red blood cell precursors.
J Pedro Fernández-Murray +10 more
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Maternal PM2.5 exposure and abnormal placental nutrient transport
Ecotoxicology and Environmental Safety, 2021 Epidemiological studies of human and animal experiments indicated that gestational exposure to atmospheric pollutants could be followed by the abnormal placental development.
Na Zhu +5 more
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, 2009 An inadequate folate status is associated with increased risk of anaemia and neural tube defects. In many countries a folate intake below recommendations has been reported for women in childbearing age.
Öhrvik, Veronica
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Haem and folate transport by proton-coupled folate transporter/haem carrier protein 1 (SLC46A1) [PDF]
British Journal of Nutrition, 2008 Haem carrier protein 1 (HCP1) was originally identified and characterised as a mammalian haem transporter. However, recent evidence has shown that it is also a proton-coupled folate transporter (PCFT) and mutations in the gene cause hereditary folate deficiency in humans.
Laftah, Abas H +5 more
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Frontiers in Pharmacology, 2016 Acute lymphoblastic leukemia (ALL) is a frequent neoplasia occurring in children. The most commonly used drug for the treatment of ALL is methotrexate (MTX), an anti-folate agent.
Fausto Zaruma-Torres +9 more
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Frontiers in Microbiology, 2019 Microbial metabolites, including B complex vitamins contribute to diverse aspects of human health. Folate, or vitamin B9, refers to a broad category of biomolecules that include pterin, para-aminobenzoic acid (pABA), and glutamate subunits.
Melinda A. Engevik +16 more
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Fetal serum folate concentrations and placental folate transport in obese women [PDF]
American Journal of Obstetrics and Gynecology, 2011 We hypothesized that fetal folate serum concentrations are lower and placental folate transport is impaired in pregnancies of obese women.Umbilical vein serum and placental tissue were collected from normal weight and obese pregnant women at term.
Margaret F, Carter +6 more
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Plants, 2022 Although the effect of folic acid (FA) and its derivatives (folates) have been extensively studied in humans and animals, their effects are still unclear in most plant species, specifically under various abiotic stress conditions.
Hameed Alsamadany +3 more
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