Results 211 to 220 of about 67,969 (299)

The Influence of Drosophila Spire and Myosin V During Mid‐Oogenesis Is Independent of Their Direct Interaction

open access: yesCytoskeleton, EarlyView.
ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong   +7 more
wiley   +1 more source

Cumulative Cytological Assessment of Repeated Non‐Diagnostic Thyroid Fine Needle Aspirations: A Novel Approach to Reduce Diagnostic Uncertainty

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Purpose Fine needle aspiration (FNA) is the primary diagnostic tool for evaluating thyroid nodules. However, 10%–21% of FNAs yield non‐diagnostic (ND) results (Bethesda category I). Repeated ND findings occur in 25%–67.5% of cases, creating diagnostic uncertainty and increased healthcare costs.
Shiri Damti Geva   +7 more
wiley   +1 more source

RORγt‐APCs: The New Masters of Oral Tolerance

open access: yesBarrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

Novel Organelle‐Based Intracellular Immunity With Mechanistic and Therapeutic Implications

open access: yesBarrier Immunity, EarlyView.
A conceptual framework illustrating how PAMPs/DAMPs initiate barrier, innate, adaptive, and intracellular immune responses, with organelle‐based intracellular immunity serving as a central integrator linking metabolism, inflammatory signaling, and therapeutic interventions to restore immune homeostasis.
Keman Xu   +9 more
wiley   +1 more source

Follicular helper-T cells restore CD8<sup>+</sup>-dependent antitumor immunity and anti-PD-L1/PD-1 efficacy. [PDF]

open access: yesJ Immunother Cancer, 2021
Niogret J   +17 more
europepmc   +1 more source

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