Results 41 to 50 of about 6,078 (136)

Activin signaling as an emerging target for therapeutic interventions

Cell Communication and Signaling, 2009
After the initial discovery of activins as important regulators of reproduction, novel and diverse roles have been unraveled for them. Activins are expressed in various tissues and have a broad range of activities including the regulation of gonadal ...
Ageta Hiroshi, Sunada Yoshihide, Uezumi Akiyoshi, Hitachi Keisuke, Nakatani Masashi, Tsuchida Kunihiro, Inokuchi Kaoru   +6 more
doaj   +1 more source

cDNA that encodes active agrin [PDF]

, 1992
Agrin is thought to mediate the motor neuron-induced aggregation of AChRs and AChE on the surface of muscle fibers at neuromuscular junctions. We have isolated a cDNA from a chick brain library that, based on sequence homology and expression experiments,
Bolander, Bourgeois, Campanelli, Chi, Dahm, Devereux, Dohrmann, Elliott, Fallon, Feinberg, Gluzman, Godfrey, Godfrey, Godfrey, Gubler, Henikoff, Hunter, Hunter, Kidd, Knust, Lankat-Buttgereit, Luthman, Magill-Solc, Magill-Solc, McMahan, Nitkin, Pearson, Pikkarainen, Pikkarainen, Ranscht, Reist, Rothberg, Ruegg, Rupp, Sambrook, Sanger, Shimasaki, Tabor, Tsim, von Heijne, Wallace, Wallace, Wilson   +42 more
core   +2 more sources

TLR3 Deficiency Leads to a Dysregulation in the Global Gene-Expression Profile in Murine Oviduct Epithelial Cells Infected with Chlamydia muridarum [PDF]

, 2019
OBJECTIVE Describe the implementation and effects of Mobile Acute Care for Elders (MACE) consultation at a Veterans Affairs Medical Center (VAMC). DESIGN Retrospective cohort analysis.
Derbigny, Wilbert A, Kumar, Ramesh
core   +2 more sources

Maternal plasma levels of follistatin‐related gene protein in the first trimester of pregnancies with Down syndrome

Prenatal Diagnosis, 2010
AbstractObjectiveTo determine maternal plasma levels of follistatin‐related gene protein (FLRG) in the first trimester of pregnancy and assess its potential role as a marker for prenatal screening of Down syndrome.MethodsMaternal plasma levels of FLRG were determined in 100 pregnant women with normal fetuses in their first trimester of pregnancy (i.e ...
Miron, P., Lambert, J., Marcil, A., Cowans, N. J., Stamatopoulou, A., Spencer, K.   +5 more
openaire   +3 more sources

Circulating organokines in coronary artery disease and metabolic syndrome: FABP4, adiponectin, irisin, FSTL1

Biomolecules & Biomedicine
Cardiovascular disorders are closely linked to metabolic syndrome and remain a leading cause of mortality worldwide, despite advances in early detection and treatment.
Meltem Uyaner Kan, İbrahim Kilinc, Hakan Akilli, Hasan Huseyin Bilgic   +3 more
doaj   +1 more source

The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass [PDF]

, 2013
Although the canonical transforming growth factor β signaling pathway represses skeletal muscle growth and promotes muscle wasting, a role in muscle for the parallel bone morphogenetic protein (BMP) signaling pathway has not been defined. We report,
Amthor, Amthor, Ball, Bayat, Bianca C. Bernardo, Bodine, Bogdanovich, Bradley J. Turner, Catherine E. Winbanks, Chung, Claudia Beyer, Clever, Cohen, Craig A. Harrison, Donaldson, Dworkin, Dworkin, Fischle, Gregorevic, Grönroos, Gurney, Hayashi, Heitman, Holley, Hongwei Qian, Ibebunjo, Imamura, Ishida, Julie R. McMullen, Justin L. Chen, Kalista, Kambadur, Katagiri, Kevin I. Watt, Langenfeld, Lars Larsson, Latres, Lee, Lee, Lee, Massagué, Mathews, McCabe, McPherron, Moresi, Musarò, Nakao, Nickel, Ochala, Paul Gregorevic, Pescatori, Potthoff, Pourquié, Rachel E. Thomson, Rafael, Rebbapragada, Rommel, Ruschke, Sako, Sandri, Sartori, Sartori, Sean L. McGee, Shioi, Stitt, Suryawan, Tang, Timothy Connor, Townsend, Trendelenburg, Winbanks, Winbanks, Yamamoto, Yingying Liu, Zhou, Zimmerman   +75 more
core   +2 more sources

Molecular Characterization of the Follistatin (FST) Gene in Quail and its Modulation through Natural Agonists [PDF]

Brazilian Journal of Poultry Science
Follistatin (FST) is a cysteine-rich monomeric protein capable of binding and neutralizing the action of several members of the transforming growth factor-beta (TGFβ) family, such as myostatin and activin, by binding to their receptors.
UlF Hassan, S Aftab, MS Rehman, S Arif, M Safdar, S Ahmed, K Ahmad, AD Cerbo, MM Azzam, M Alagawany   +9 more
doaj   +1 more source

PACAP induces FSHβ gene expression via EPAC. [PDF]

, 2019
Gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), are heterodimers of a common α subunit and unique β subunits. Regulation of their levels, primarily by GnRH, is critical for reproductive function.
Coss, Djurdjica, Yeh, Debra M
core  

Follistatin-like 5 is expressed in restricted areas of the adult mouse brain: Implications for its function in the olfactory system [PDF]

, 2014
Follistatin‐like 5 (Fstl5), a member of the follistatin family of genes, encodes a secretory glycoprotein. Previous studies revealed that other members of this family including Fstl1 and Fstl3 play an essential role in development, homeostasis, and ...
Masuda Tomoyuki, Nagaoka Atsuko, Nagase Takahiro, Sakuma Chie, Ueda Shuichi, Yaginuma Hiroyuki, Yamagishi Toshiyuki, 増田 知之   +7 more
core   +2 more sources

Different effect of follistatin-related protein (FRP)in ox-LDLinduced endothelial cell and vascular smooth muscle cell apoptosis [PDF]

Heart, 2011
Background The development of atherosclerosis proceeds through multiple maladaptive pathways that begins with endothelial cell (EC)injury caused by oxidised low-density lipoprotein (ox-LDL) which plays a critical role. Proliferation and migration of vascular smooth muscle cells (VSMCs) also play an important role in
null Shenhua, Liu Yuyang, Wang Zhijian, Yang Shiwei, null Hanhongya, Ge Hailong, Xiao-Li Liu, null Jiadean, Gao fei   +8 more
openaire   +1 more source