Results 51 to 60 of about 12,023,937 (197)
AnimalsActivin is a dimeric growth factor with diverse biological activities in vertebrates. This study aimed to investigate the regulatory role of the activin signaling pathway in the ovary of the endangered, cultured sturgeon species Acipenser sinensis.
Huamei Yue +4 more
doaj +1 more source
Molecular Characterization of the Follistatin (FST) Gene in Quail and its Modulation through Natural Agonists [PDF]
Brazilian Journal of Poultry ScienceFollistatin (FST) is a cysteine-rich monomeric protein capable of binding and neutralizing the action of several members of the transforming growth factor-beta (TGFβ) family, such as myostatin and activin, by binding to their receptors.
UlF Hassan +9 more
doaj +1 more source
Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing
Animal Research and One Health, EarlyView.Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley +1 more source
Physiological roles of activins in the human ovary
Journal of Bio-X Research, 2018 . Initially discovered in the pituitary as stimulators of follicle stimulating hormone, activins are homo- or heterodimers of inhibin subunits, which belong to the transforming growth factor-β superfamily.
Hsun-Ming Chang, Peter C.K. Leung
doaj +1 more source
Obesity Reviews, EarlyView.ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is the most common chronic liver disorder worldwide, affecting approximately one‐third of the population and increasing the risk of severe hepatic and cardiovascular complications.
Shurui Yang +4 more
wiley +1 more source
Photochemistry and Photobiology, Volume 101, Issue 2, Page 338-349, March/April 2025.In the present work with mouse models, we demonstrate that a novel compound, NEO400, is able to profoundly protect skin against damage caused by UV radiation (UVR) when it is applied to skin post‐UVR exposure. In comparison, Aloe vera or linoleic acid are unable to achieve a similar level of protection.
Stephen Swenson +6 more
wiley +1 more source
Putting the brakes on muscle growth: Myostatin as regulator of disuse atrophy
Experimental Physiology, EarlyView.Abstract Skeletal muscle is a highly plastic tissue that rapidly adapts to changes in mechanical loading and metabolic activity. Periods of inactivity, including bed rest, limb immobilization or microgravity, induce a pronounced loss of muscle mass and function.
Derk H. C. Nieuwenhuijsen +2 more
wiley +1 more source
Follistatin‐related protein/follistatin‐like 1 evokes an innate immune response via CD14 and toll‐like receptor 4 [PDF]
FEBS Letters, 2012 FRP physically interacts with CD14 by fluorescence‐activated cell sorting (View interaction)
Murakami, Kosaku +13 more
openaire +2 more sources
, 2017 Background: A previous study suggested that activin A inhibited myocardial cell apoptosis. This study thus aimed to explore the effects of the activin A–follistatin system on myocardial cell apoptosis in heart failure (HF) rats in order to determine ...
Cuiying Mao +4 more
core +1 more source
Pegylated Interferon-α Modulates Liver Concentrations of Activin-A and Its Related Proteins in Normal Wistar Rat [PDF]
, 2015 Aims. To measure the expression of activin βA-subunit, activin IIA and IIB receptors, Smad4, Smad7, and follistatin in the liver and the liver and serum concentrations of mature activin-A and follistatin in normal rat following treatment with pegylated ...
Noha Mohammed Al-Qadi +4 more
core +1 more source