Results 41 to 50 of about 12,023,937 (197)

Identification of NF-kappaB responsive elements in follistatin related gene (FLRG) promoter

, 2007
Follistatin related gene (FLRG) has been previously identified from a chromosomal translocation observed in a B-cell chronic lymphocytic leukemia (B-CLL).
Stéphane Guindon, Ruth Rimokh, Laurent Bartholin, Laura Corbo, Corbo, Laura, Martel, Sylvie, Sylvie Martel, Rimokh, Ruth, Bartholin, Laurent, Guindon, Stéphane   +9 more
core   +1 more source

The activin binding proteins follistatin and follistatin-related protein are differentially regulated in vitro and during cutaneous wound repair [PDF]

Journal of Endocrinology, 2001
Abstract Follistatin is a secreted protein that binds activin in vitro and in vivo and thereby inhibits its biological functions. Recently, related human and murine genes, designated follistatin-related gene (FLRG), were identified, and their products were shown to bind activin with high affinity.
Wankell M, Kaesler S, Zhang YQ, Florence C, Werner S, Duan R   +5 more
openaire   +3 more sources

Follistatin-related gene expression, but not follistatin expression, is decreased in human endometrial adenocarcinoma

, 2004
OBJECTIVE: Activin A is a multifunctional growth and cell differentiation factor produced by normal endometrium, and secreted in high amounts by endometrial adenocarcinoma.
FLORIO, P., CIARMELA, P., RIMOKH, R., SIGURDARDOTTIR, M., TOSI, P., ALTOMARE, A., PETRAGLIA, F., TOTI, P., MAGUER-SATTA, V., Petraglia, Felice   +9 more
core   +1 more source

Differential expression and release of activin A and follistatin in chronic rhinosinusitis with and without nasal polyps [PDF]

, 2015
Background : Chronic rhinosinusitis with (CRSwNP) and without nasal polyps (CRSsNP) should be regarded as distinct clinical entities based on differential inflammatory mediator and remodeling profiles.
Hu, Guohua, Yang, Yucheng, Van Crombruggen, Koen, Claus Bachert, Bachert, Claus, Zhang, Nan, Feng Lan, Koen Van Crombruggen, Lan, Feng, Suling Hong, Hong, Suling, Yucheng Yang, Guohua Hu, Nan Zhang, Hong Suling, Lan, F, Zhang Nan, Van, Crombruggen K, Hong, S, Yang Yucheng, Yang, Y, Hu, G, Crombruggen Koen Van, Bachert Claus, Lan Feng, Bachert, C,, Hu Guohua, Zhang, N   +27 more
core   +1 more source

Activin signaling as an emerging target for therapeutic interventions

Cell Communication and Signaling, 2009
After the initial discovery of activins as important regulators of reproduction, novel and diverse roles have been unraveled for them. Activins are expressed in various tissues and have a broad range of activities including the regulation of gonadal ...
Ageta Hiroshi, Sunada Yoshihide, Uezumi Akiyoshi, Hitachi Keisuke, Nakatani Masashi, Tsuchida Kunihiro, Inokuchi Kaoru   +6 more
doaj   +1 more source

Circulating organokines in coronary artery disease and metabolic syndrome: FABP4, adiponectin, irisin, FSTL1

Biomolecules & Biomedicine
Cardiovascular disorders are closely linked to metabolic syndrome and remain a leading cause of mortality worldwide, despite advances in early detection and treatment.
Meltem Uyaner Kan, İbrahim Kilinc, Hakan Akilli, Hasan Huseyin Bilgic   +3 more
doaj   +1 more source

Multifunctional Nanovaccine‐Radiotherapy Synergy Drives Anti‐Tumor Immunity via Multi‐Cascade Cell Death for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through
Chengyi Huang, Yushu Han, Xiang Liu, Chuanhao Wang, Xiaofei Zhu, Di Chen, Yangyang Gong, Liang Chen, Wenjuan Chen, Zhenyuan Miao, Bufu Tang, Huojun Zhang   +11 more
wiley   +1 more source

Association between follistatin-related protein 1 and the functional status of patients with anti-neutrophil cytoplasmic antibody-associated vasculitis

Chinese Medical Journal, 2021
Abstract Background: Follistatin-like 1 (FSTL1) plays both pro-inflammatory and anti-inflammatory roles in the inflammatory processes. We investigated whether serum FSTL1 could predict the current anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV)-specific indices ...
Taejun Yoon, Sung Soo Ahn, Jung Yoon Pyo, Jason Jungsik Song, Yong-Beom Park, Sang-Won Lee, Li-Shao Guo   +6 more
openaire   +4 more sources

RUNX1‐Mediated Hypoxic Signaling Impairs Myogenesis and Promotes Fibrosis in Myopathies

Advanced Science, EarlyView.
Myofiber overgrowth was associated with reduced blood flow and a potential hypoxic state in broiler breast muscle, accompanied by increased RUNX1 expression. Elevated RUNX1 impaired myogenic regeneration, promoted fibrosis, and disrupted the signaling niche required for efficient muscle repair, contributing to pathological degeneration in Wooden Breast
Liang Zhao, Taijiang Hou, Lin Zhang, Feng Gao, Tong Xing   +4 more
wiley   +1 more source

Ameliorative effects of follistatin‐related protein/TSC‐36/FSTL1 on joint inflammation in a mouse model of arthritis [PDF]

Arthritis & Rheumatism, 2004
AbstractObjectiveTo clarify the in vivo function of follistatin‐related protein (FRP)/TSC‐36/FSTL1 in rheumatoid arthritis (RA), we investigated the roles of FRP in a mouse model of arthritis.MethodsArthritis was induced in BALB/c mice by injecting anti–type II collagen monoclonal antibody and lipopolysaccharide.
Daisuke, Kawabata, Masao, Tanaka, Takao, Fujii, Hisanori, Umehara, Yoshimasa, Fujita, Hajime, Yoshifuji, Tsuneyo, Mimori, Shoichi, Ozaki   +7 more
openaire   +2 more sources