Results 41 to 50 of about 19,656 (205)

In-vitro study of the effect of anti-hypertensive drugs on placental hormones and angiogenic proteins synthesis in pre-eclampsia [PDF]

, 2014
Antihypertensive drugs lower the maternal blood pressure in pre-eclampsia (PE) by direct or central vasodilatory mechanisms but little is known about the direct effects of these drugs on placental ...
Gangooly, S, Jauniaux, E, Muttukrishna, S   +2 more
core   +7 more sources

FSTL5 expression is a marker of Group C metastatic medulloblastomas [PDF]

, 2014
INTRODUCTION: Medulloblastoma (MB) is the most commonmalignant brain tumor in children. Four different molecular subgroups are recognized, which differ in gene expression, genomic aberrations, histology, demographics and survival:WNT and SHH groups ...
Baldi, Caterina, Buttarelli, Francesca Romana, Giangaspero, Felice, Gianno, Francesca, Massimino, Maura, Minasi, Simone   +5 more
core   +1 more source

Clinical significance of serum follistatin levels in the diagnosis of ovarian endometrioma and benign ovarian cysts

Taiwanese Journal of Obstetrics & Gynecology, 2015
Objective: To determine the clinical significance of serum follistatin levels in women with an ovarian endometrioma. Materials and methods: This is a prospective study of 89 women, 56 with an ovarian endometrioma (endometrioma group) and 33 with a benign
Ömer Ant, Gülnur Özakşit, Ali İrfan Güzel, Sabri Cavkaytar, Metin Kaba, Hasan Onur Topçu   +5 more
doaj   +1 more source

Follistatin as potential therapeutic target in prostate cancer [PDF]

, 2013
Follistatin is a single-chain glycosylated protein whose primary function consists in binding and neutralizing some members of the transforming growth factor-β superfamily such as activin and bone morphogenic proteins.
CRESCIMANNO, Marilena, DI MAJO, Danila, FLANDINA, Carla, GIAMMANCO, Marco, LA GUARDIA, Maurizio, LETO, Gaetano, Sepporta, MV, TUMMINELLO, Francesca Maria   +7 more
core   +1 more source

Inhibiting Myostatin with Follistatin Improves the Success of Myoblast Transplantation in Dystrophic Mice

Cell Transplantation, 2008
Duchenne muscular dystrophy is a recessive disease due to a mutation in the dystrophin gene. Myoblast transplantation permits to introduce the dystrophin gene in dystrophic muscle fibers.
Basma F. Benabdallah, Manaf Bouchentouf, Joel Rousseau, Pascal Bigey, Annick Michaud, Pierre Chapdelaine, Daniel Scherman, Jacques P. Tremblay   +7 more
doaj   +1 more source

Follow the follistatin [PDF]

Science-Business eXchange, 2008
Ohio State University and Nationwide Children's Hospital researchers have reported on the use of gene therapy to deliver follistatin to treat muscular dystrophy, a disease that is still confounding drug developers.
openaire   +1 more source

Follistatin Protein Enhances Satellite Cell Counts in Reinnervated Muscle

Journal of Brachial Plexus and Peripheral Nerve Injury, 2022
Background Muscle recovery following peripheral nerve repair is sup-optimal. Follistatin (FST), a potent muscle stimulant, enhances muscle size and satellite cell counts following reinnervation when administered as recombinant FST DNA via viral vectors ...
Mark A. Feger, Jonathan Isaacs, Satya Mallu, Dorne Yager, Mary Shall, Gaurangkumar Patel, Omar Protzuk, Akhil S. Bokkisam   +7 more
doaj   +1 more source

Human activin-A is expressed in the atherosclerotic lesion and promotes the contractile phenotype of smooth muscle cells [PDF]

, 1999
Activin is a member of the transforming growth factor-beta superfamily, and it modulates the proliferation and differentiation of various target cells. In this study, we investigated the role of activin in the initiation and progression
Achterberg, T.A.E. (Tanja) van, Aken, B.E. (Benien) van, Engelse, M.A. (Marten), Neele, J.M., Pannekoek, H. (Hans), Schaik, R.H.N. (Ron) van, Vries, C.J.M. (Carlie) de   +6 more
core   +3 more sources

Novel Roles of Follistatin/Myostatin in Transforming Growth Factor-β Signaling and Adipose Browning: Potential for Therapeutic Intervention in Obesity Related Metabolic Disorders

Frontiers in Endocrinology, 2021
Obesity is a global health problem and a major risk factor for several metabolic conditions including dyslipidemia, diabetes, insulin resistance and cardiovascular diseases.
Shehla Pervin, Shehla Pervin, Srinivasa T. Reddy, Srinivasa T. Reddy, Rajan Singh, Rajan Singh, Rajan Singh   +6 more
doaj   +1 more source

Roles of intracerebral activin, inhibin, and follistatin in the regulation of Kiss-1 gene expression: Studies using primary cultures of fetal rat neuronal cells

Biochemistry and Biophysics Reports, 2020
Hypothalamic kisspeptin, encoded by the Kiss-1 gene, governs the hypothalamic-pituitary-gonadal axis by directly regulating the release of gonadotropin-releasing hormone.
Zolzaya Tumurgan, Haruhiko Kanasaki, Tuvshintugs Tumurbaatar, Aki Oride, Hiroe Okada, Satoru Kyo   +5 more
doaj   +1 more source