Results 51 to 60 of about 419,442 (300)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Impact of mechanical and microstructural properties of potato puree-food additive complexes on extrusion-based 3D printing [PDF]

, 2018
This paper studies the applicability of extrusion-based 3D printing for constructing novel shapes from potato puree and the effects of four additives (agar, alginate, lecithin, and glycerol) added separately at three concentrations (0.5, 1, 1.5%) on the ...
Dankar, Iman, El Omar, Fawaz, Haddarah, Amira, Pujolà Cunill, Montserrat, Sepulcre Sánchez, Francesc   +4 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Dietary non-phytate phosphorus and phytase interaction affects growth performance, mineral transportation and metabolism in broiler chickens

Poultry Science
The interaction effects of dietary non-phytate phosphorus (NPP) and phytase on growth performance, mineral metabolism, and gene expressions of mineral transporters in broilers duodenum and kidney (0-3 weeks) were studied. The levels of NPP (0.45 %, 0.35 %
Bingbing Ma, Yan Zhang, Mengyuan Liu, Chuanxin Shi, Yu Zhou, Mengyue Chen, Yuchun Chang, Hongxia Qu, Liao Zhang, Chunmei Zhang, Guanhua Chen, Jincheng Han   +11 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

MAPK signaling pathway participates in the regulation of intestinal phosphorus and calcium absorption in broiler chickens via 1,25-dihydroxyvitamin D3

Poultry Science
: Four experiments were performed to investigate the role of the mitogen-activated protein kinase (MAPK) signaling pathway in intestinal absorption of phosphorus (P) and calcium (Ca) in broiler chickens.
Jincheng Han, Xianliang Lv, Lei He, Mengyuan Liu, Hongxia Qu, Li Xi, Liao Zhang, Bingbing Ma, Chuanxin Shi, Guangli Yang, Zhixiang Wang   +10 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Atomic-Scale Mechanisms of Catalytic Recombination and Ablation in Knitted Graphene Under Hyperthermal Atomic Oxygen Exposure

C
Effective ablative thermal protection systems are essential for ensuring the structural integrity of hypersonic vehicles subjected to extreme aerothermal loads.
Yating Pan, Yunpeng Zhu, Donghui Zhang, Ning Wei   +3 more
doaj   +1 more source

Manipulating the ensilage of wilted, unchopped grass through the use of additive treatments [PDF]

, 2007
peer-reviewedBaled silage composition frequently differs from that of comparable conventional precision-chop silage. The lower final concentration of fermentation products in baled silage makes it more conducive to the activities of undesirable ...
Clipson, Nicholas J.W., Doyle, Evelyn M., Forristal, P.D., McEniry, Joseph, O'Kiely, Padraig   +4 more
core