Results 151 to 160 of about 456,401 (242)

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

Advanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon, Mireille Elodie Tsitokana, Ugo Guy Alenda, Yen‐Ling Lian, Clémentine Eva Philibert, Mathieu Oosterlaken, Marta Cimadevila, Gaëlle Dudon, Jessica Monnic, Salomé Roux, Julie Bessié, Séverine Diem, Franck Vandermoere, Laurent Prézeau, Patrick Chames, Julie Kniazeff, Sylvie Claeysen, Anaïs Menny, Jean‐Philippe Pin, Véronique Perrier, Jianfeng Liu, Philippe Rondard   +21 more
wiley   +1 more source

HACCP plan fresh fish processing Marituna [PDF]

, 2003
In the past regulatory authorities for food products had a duty to ensure that foods offered tothe consumer are at least safe to eat. The authorities required a positive approach of using Good Manufacturing Practices (GMP), producing food in a hygienic ...
Aalberts, C.H.J.
core   +1 more source

Food and feed safety vulnerabilities in the circular economy

EFSA Supporting Publications, 2022
Katy James, Anthony Millington, Nicola Randall   +2 more
openaire   +1 more source

Problem formulation: GMO and safety assessment of food and feed

, 2016
Share experiences regarding the application of the criteria based on the Principles and Guidelines for the safety assessment of foods derived from modern biotechnology by Codex Alimentarius in Latin America.
openaire   +1 more source

Hepatoma‐Derived Growth Factor Coordinates STAT3 Pathway and Exosome‐Mediated Intrahepatic Crosstalk to Control Hepatic Steatosis and MASLD

Advanced Science, EarlyView.
Hepatic HDGF as a key mediator in coordinating hepatic steatosis and intrahepatic crosstalk in MASLD. Activation of HDGF facilitates its interaction with both STAT3 and S6K1, driving the S6K1‐dependent STAT3 phosphorylation and subsequently enhancing hepatic lipogenesis.
Jian Wen, Dong Ding, Zengpeng Zheng, Xufeng Chen, Wenjing Li, Jiaxin Shen, Zhiwei Huang, Peng Tan, Junjie Bai, Xia Fang, Baofang Xing, Puyuan Hu, Linghao Xu, Haokai Yu, Yixi Wang, Zongzhe Jiang, Yang Long, Tiejun Zhou, Mingxin Ye, Yu Jiang, Aoyuan Cui, Hong Li, Qiurong Ding, Yong Xu, Yu Li, Weitong Su, Feng Shen, Chenlin Gao, Wenguang Fu   +28 more
wiley   +1 more source

Energy input and output of a rural village in China - the cas of the "Beijing Man village" /District of Beijing [PDF]

, 2006
The rapid development of the economy has created an increasing demand for energy in China. The limited resources of fossil energy are a risk for the development of China.
Cong, Lin, Rahmann, PD Dr. Gerold, Shi, Chenlu, Sun, Prof. Zhenjun, Sun, Yongming, Wei, Xiaoming   +5 more
core  

Sustainable Materials Design With Multi‐Modal Artificial Intelligence

Advanced Science, EarlyView.
Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu, Tianshuo Wei, Yan Ge, Bo Peng, Yue Li, Maolin Wang, Peng Wen, Chao Yang, Ye Wei   +8 more
wiley   +1 more source

Did farmers’ livelihood improve? An impact assessment of incorporating forages into the crop-livestock system in the coastal savannah zone of Ghana [PDF]

The study used programming methods to assess the farm-level impact of incorporating forages, including dual purpose Cajanus cajan (C. cajan), into the crop-livestock system in the Coastal Savannah Zone of Ghana.
Aboe, P.A.T., Ameleke, G.Y., Marfo-Ahenkora, E.A., Okantah, S.A., Sottie, E.T.   +4 more
core   +1 more source

Nutritional and Safety Assessments of Foods and Feeds Nutritionally Improved through Biotechnology [PDF]

Food and Nutrition Bulletin, 2005
Chassy, B., Hlywka, J.J., Kleter, G.A., Kok, E.J., Kuiper, H.A., McGloughlin, M., Munro, I.C., Phipps, R.H., Reid, J.E., Stein, J., Zabik, J.   +10 more
openaire   +3 more sources

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source