Dissolvable microneedle (MN) device containing Bacillus paralicheniformis. The polymeric matrix encapsulates and protects the bacteria, preserving their viability while enabling in situ production and release of γ‐polyglutamic acid. The bacteria are delivered into the skin via 500 µm‐long microneedles, and remain detectable on the skin 24 h post ...
Caroline Hali Alperovitz +3 more
wiley +1 more source
Safety evaluation of the food enzyme phospholipase D from the non-genetically modified <i>Streptomyces netropsis</i> strain DSM 40093. [PDF]
EFSA Panel on Food Enzymes (FEZ) +17 more
europepmc +1 more source
Spherical bioactive glass nanoparticles containing strontium inhibit osteoclast differentiation and activity, but promote osteoblast activity in osteoblast‐osteoclast in vitro co‐culture. The nanoparticles could be used for the treatment of osteoporosis.
Parichart Naruphontjirakul +2 more
wiley +1 more source
Safety evaluation of the food enzyme cellulase from the non-genetically modified <i>Aspergillus niger</i> strain AC 4-984. [PDF]
EFSA Panel on Food Enzymes (FEZ) +16 more
europepmc +1 more source
Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami +4 more
wiley +1 more source
Safety evaluation of the food enzyme endo-1,3(4)-β-glucanase from the non-genetically modified <i>Trichoderma reesei</i> strain TG-M5-337. [PDF]
EFSA Panel on Food Enzymes (FEZ) +20 more
europepmc +1 more source
Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
Safety evaluation of the food enzyme glucan 1,4-α-maltohydrolase from the genetically modified <i>Trichoderma reesei</i> strain DP-Nyn90. [PDF]
EFSA Panel on Food Enzymes (FEZ) +16 more
europepmc +1 more source
Advances in Bioprinting to Model Immune‐Mediated Skin Diseases
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández +4 more
wiley +1 more source
Safety evaluation of the food enzyme endo-1,4-β-xylanase from the non-genetically modified <i>Aspergillus luchuensis</i> strain DP-Azd103. [PDF]
EFSA Panel on Food Enzymes (FEZ) +18 more
europepmc +1 more source

