Results 141 to 150 of about 236,529 (244)
Carrion ecology: concepts, interdisciplinary synthesis, and perspectives
Biological Reviews, EarlyView.ABSTRACT Carrion is a ubiquitous resource in both terrestrial and aquatic ecosystems, yet it has long been overlooked in ecological research. Over the past two decades, studies on carrion and the many organisms that exploit it have flourished, revealing not only wide‐ranging ecological functions but also significance far beyond ecology.
Marcos Moleón +38 more
wiley +1 more source
Business Strategy and the Environment, EarlyView.ABSTRACT Despite growing attention to the circular bioeconomy (CBE), the steel industry currently lacks a standardised, sectoral measurement framework to facilitate a low‐carbon transition. In this study, a decision‐support framework for evaluating CBE performance in the steel industry is proposed.
Ali Zamani Babgohari +2 more
wiley +1 more source
Protein hydrolysates in cell culture: Toward multi‐omics characterization
Biotechnology Progress, EarlyView.While protein hydrolysates are widely used in cell culture applications, they remain undefined and variable products. Multi‐omic characterization evaluating composition and function can transition hydrolysates toward semi‐defined media components.
Michelle Combe +3 more
wiley +1 more source
Biotechnology Progress, EarlyView.Abstract We investigated side‐by‐side clarification with a two‐stage depth filter system against a single‐stage charge chromatographic clarifier on a number of Chinese hamster ovary (CHO) cell cultures. We found that the one‐stage fibrous anion exchange (AEX) clarification met or exceeded the performance of the conventional two‐stage depth filtration ...
Hendri Tjandra +7 more
wiley +1 more source
Biotechnology Progress, EarlyView.Abstract Applying a single parameter set to describe complex mammalian kinetics often is too simplistic, as it fails to capture sensitive cell‐to‐environment interactions that may be exploited to optimize production performance. To resolve this time dependency, intra‐experimental parameter shifts as part of design of dynamic experiments (DoDE) can be ...
Samuel Kienzle +7 more
wiley +1 more source
Purification and concentration of model viruses using single‐pass tangential flow filtration
Biotechnology Progress, EarlyView.Single‐pass TFF was developed for an enveloped and non‐enveloped virus for use in continuous downstream purification processes. Enveloped virus was concentrated and purified. Abstract The vaccine and viral vector industry is growing at an accelerated rate.
Luis Alberto Mejía‐Manzano +6 more
wiley +1 more source
Status and future of recombinant adeno‐associated virus vector manufacturing
Biotechnology Progress, EarlyView.Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley +1 more source
Viscosity of concentrated mRNA solutions: Implications for downstream processing
Biotechnology Progress, EarlyView.Abstract Messenger RNA (mRNA) therapeutics can be used to protect against infectious disease and for the treatment of cancers and genetic disorders. In order to obtain the desired therapeutic dosage, it is necessary to concentrate the mRNA to levels where the viscosity of the mRNA solutions can become significant.
Amin Javidanbardan +3 more
wiley +1 more source