Results 41 to 50 of about 6,209,209 (292)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Global collective practices advancing food sovereignty in indigenous and peasant communities: a systematic review

Frontiers in Sustainable Food Systems
This article examines food sovereignty practices, focusing on the experiences of peasants and Indigenous communities as key actors in both implementation and discourse.
Yeismy Amanda Castiblanco Venegas, Carlos Andrés Rincón Arias, Jenny Nataly Sanabria Niño, Jenny Nataly Sanabria Niño   +3 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Development of Biodegradable Rosemary Essential Oil-Based Biofilm for Enhanced Preservation of Strawberries [PDF]

BIO Web of Conferences
Strawberries, or Fragaria ananassa, are among the most economically perishable fruits; postharvest losses of 40–50% are mostly caused by Alternaria alternata, a kind of fungus. The manufacture and antifungal assessment of a biodegradable biofilm based on
Kumari Sneha, Sharma Abhishek, Kaushik Nutan, Ghanghas Sachin, Bhattacharya Arpita   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Scottish Food Practices: Household food practices and the use of dietary information

, 2020
This report presents findings from The Scottish Food Practices study, designed to investigate what and how households across Scotland use dietary information (if at all) when cooking/eating at home, shopping for food and eating outside the home.The study aims to inform the work of Food Standards Scotland (FSS) as they develop new dietary guidance that ...
Wills, Wendy J., Vaghi, Francesca, Geddes, Kevin, Hamilton, Laura   +3 more
openaire   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Priority research questions for the UK food system [PDF]

, 2013
The rise of food security up international political, societal and academic agendas has led to increasing interest in novel means of improving primary food production and reducing waste.
Ingram, John S I, Tassou, S., Benton, Tim G., Miller, Anne, Dolan, Catherine S, Sutherland, William J, Timothy Aldred, Knox, J. W., Kaiser, M.J., Norton, Ian T., Macdiarmid, Jennie I, Fitzpatrick, JL, Quested, TE, Murray, C, Kennard, R., Crossley, Daniel S., McGonigle, D.F., Macdiarmid, Jennie I., Terry, L. A., Murray, Calum, Finney, K. J., Ian T. Norton, Brocklehurst, Tim F., Leon A. Terry, Judith Buttriss, Millar, S.J., Brocklehurst, Tim F, Mead, Angela, Terry, Leon A, John Casey, William Vorley, Charles S. Bestwick, Benton, T.G., Crossley, D.S., Kuyk, A., Jennie I. Macdiarmid, Buttriss, J, Kuyk, A, Wright, HL, Bows-Larkin, A., Crossley, D. S., Martindale, Wayne, Brocklehurst, T. F., Garrett, D.A., Kaiser, Michel J.; id_orcid, Stephen Parry, Kennard, Robert, Foster, Lucy, Houlston, Eleanor J, Fowler, M., Dolan, C.S., Buttriss, Judith, Mathers, J. C., Daniel S. Crossley, Benton, Tim G, Mead, A., Alice Bows-Larkin, Kaiser, Michel J, Mathers, J.C., David Barling, Catherine S. Dolan, Houlston, EJ, McGonigle, Daniel F., Finney, Karen J, Mead, A, Marilena Pollicino, Garrett, David A., Murray, C., Aldred, Timothy, Michel J. Kaiser, Ingram, J. S. I., Norton, I.T., Hugh L. Wright, Millar, Samuel J, Andrew Kuyk, Edwards, R., Casey, J, Linter, B.R., Fowler, M, van de Graaf, P., Vorley, W., Bows-Larkin, Alice; id_orcid, Aldred, T., Paul M. Berryman, Tiffin, R, Parry, S., Macdiarmid, JI, Foster, L, Andrew Godley, Calum Murray, Martindale, W., Fitzpatrick, J.L., Pollicino, Marilena, Berryman, Paul M, Robert Edwards, Collins, H, Finney, KJ, Quested, Thomas E, McGonigle, DF, Griffiths, W., Martindale, W, Garrett, David A, Dowler, Elizabeth, Fowler, Mark, Linter, Bruce R, Angela Mead, Fitzpatrick, J. L., Edwards, Robert, Norton, I. T., Millar, Samuel J., Thomas E. Quested, Robert Kennard, Bestwick, C. S., Vorley, William, Ingram, JSI, Tim G. Benton, Barling, D., Sutherland, William J., Dolan, Catherine S., Brocklehurst, T.F., Godfrey, J.E., McGonigle, Daniel F, Tassou, S, Jim E. Godfrey, Linter, B. R., Macdiarmid, J.I., William J. Sutherland, Terry, L.A., Godley, A., Kaiser, Michel J., Casey, J., Karen J. Finney, Julie L. Fitzpatrick, Wright, Hugh, Wright, H.L., Vorley, W, Aldred, Tim, Andrew Westby, Mathers, JC, Knox, Jerry W, Mathers, John C, Miller, A., Godley, A, Casey, John, Ingram, John S. I., Berryman, P.M., et, al, Finney, Karen J., Dowler, E, Fitzpatrick, Julie L, Garrett, DA, Graaf, P, Wright, H. L., Godfrey, Jim E, Elizabeth Dowler, David A. Garrett, Bestwick, Charles S, Bows-Larkin, Alice, McGonigle, D. F., Westby, A, Crossley, Daniel S, Houlston, E.J., Eleanor J. Houlston, Dowler, E., Berryman, PM, Finney, K.J., Crossley, DS, Kennard, R, Macdiarmid, J. I., Benton, T., Quested, T.E., John S. I. Ingram, Benton, TG, Brocklehurst, TF, Foster, L., Tiffin, R., Norton, Ian T, Dolan, CS, Godley, Andrew, Pollicino, M., Griffiths, William, William Griffiths, Barling, David, Linter, BR, Pieter van de Graaf, Parry, S, Ingram, J.S.I., Wright, Hugh L, Aldred, T, van de Graaf, Pieter, Sutherland, WJ, Lucy Foster, Westby, A., Bows-Larkin, A, Knox, J.W., Norton, IT, Millar, SJ, Knox, JW, Tim F. Brocklehurst, Graaf, P., Knox, Jerry W., Kuyk, Andrew, Tassou, Savvas, Dolan, C. S., Collins, Hannah, Mathers, John C., Wright, Hugh L., Collins, H., Sutherland, W. J., Pieter, van de Graaf, Samuel J. Millar, Dolan, Catherine, Godfrey, Jim E., Bestwick, CS, Houlston, Eleanor J., Kaiser, MJ, Bestwick, C.S., Daniel F. McGonigle, Ingram, John S.I., Berryman, Paul M., John C. Mathers, Anne Miller, Parry, Stephen, Sutherland, W.J., Buttriss, J., Berryman, P. M., Linter, Bruce R., Quested, Thomas E., Savvas Tassou, Godfrey, JE, Richard Tiffin, Wayne Martindale, Miller, A, Terry, LA, Fitzpatrick, Julie L., Barling, D, Griffiths, W, Edwards, R, Millar, S. J., Tiffin, Richard, Jerry W. Knox, Godley, Andrew R., Terry, Leon A., Pollicino, M, Hannah Collins, Bruce R. Linter, Ingram, John, Bestwick, Charles S., Mark Fowler, Westby, Andrew   +249 more
core   +1 more source

Relações entre soberania alimentar, práticas alimentares e conflito territorial na comunidade Quilombola Angelim I/Food sovereignty, food practices and territorial conflict in the Quilombola community Angelim I - Sapê do Norte (ES)

Geografares, 2018
This article presents reflections about the relationship between food sovereignty, food practices and territory in the quilombola community Angelim I, in the “Sapê do Norte” region, state of Espírito Santo, based on part of the author's master's research,
Isabela Leão Ponce Pasini
doaj