Results 101 to 110 of about 4,299,063 (294)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Values, attitudes, and goals of future Hungarian food engineers [PDF]
Over the last few decades Hungarian higher education has been radically transformed, and this transformation was implemented to counter the backwardness that previously plagued the education system.
Hajdu, Istvanne, Lakner, Zoltan
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No. 08: Climate Change and Food Security in Southern African Cities [PDF]
, 2011 The current urban transition in the Global South is at the heart of discussions about the relationship between climate change and food security. This paper explores the links between climate change and food security within the context of the urban ...
Frayne, Bruce, Ziervogel, Gina
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
A Historical Review of the Technology Used for the Study of Freshness in Red Meats
IEEE AccessMeat is a high-quality source of protein, vitamins, and minerals, making it a fundamental component of the human diet. Ensuring the availability of fresh meat is, therefore, essential for both consumers and the food industry.
Julieta Nava-Granados +3 more
doaj +1 more source
Effect of traditional and oven roasting on the physicochemical properties of fermented cocoa beans
Heliyon, 2018 The objective of this study was to determine the effect of oven and traditional roasting on the polyphenol content, antioxidant activity, lipid quality, proximate composition and mineral content of fermented cocoa beans.
Fabrice Tonfack Djikeng +10 more
doaj +1 more source
Food Labels: Implications for U.S. Agricultural Imports [PDF]
Labels have been used to make food attributes transparent and to satisfy the increasing consumer demand for information about food credence values. Several types of prevalent U.S.
Henneberry, Shida Rastegari +1 more
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Review of perspectives applied in the assessment of organic food networks [PDF]
, 2012 Value is a key concept for understanding how organic food networks function because values are the foundation of the organic production practice, thus value must be given a significant role in assessing and balancing the effects of organic food networks.
Alrøe, Hugo Fjelsted +2 more
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