Results 11 to 20 of about 56,919 (302)
Phylogenetic analysis of forkhead transcription factors in the Panarthropoda. [PDF]
Dev Genes Evol, 2022 AbstractFox genes encode transcription factors that contain a DNA binding domain, the forkhead domain, and are known from diverse animal species. The exact homology of the Fox genes of different species is debated and this makes inferences about the evolution of the Fox genes, and their duplications and losses difficult.
Schomburg C, Janssen R, Prpic NM.
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FoxP4, a novel forkhead transcription factor [PDF]
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 2003 Forkhead proteins have been demonstrated to play key roles in embryonic development, cell cycle regulation, and oncogenesis. We report the characterization of a new forkhead transcription factor, which is a member of the FoxP subfamily. In adult tissues FoxP4 is expressed in heart, brain, lung, liver, kidney, and testis. By Northern hybridization, very
Andreas Teufel +4 more
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Forkhead transcription factors in chronic inflammation. [PDF]
Int J Biochem Cell Biol, 2010 Forkhead (Fox) transcription factors have been increasingly recognized to play key roles in immune homeostasis, especially Foxp3 for its role in the development and function of regulatory T cells, and Foxo family members for their regulatory role in T and B lymphocytes as well as other leukocytes.
Peng SL.
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Unified nomenclature for the winged helix/forkhead transcription factors [PDF]
Genes & Development, 2000 Klaus H. Kaestner +2 more
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Forkhead transcription factors and cardiovascular biology. [PDF]
Circ Res, 2008 The Forkhead family of transcription factors modulates a wide variety of cellular functions in cardiovascular tissues. In this review article, we discuss recent advances in our understanding of regulation provided by the forkhead factors in cardiac myocytes and vascular cells.
Papanicolaou KN, Izumiya Y, Walsh K.
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Forkhead transcription factors regulate mosquito reproduction [PDF]
Insect Biochemistry and Molecular Biology, 2007 Forkhead-box (Fox) genes encode a family of transcription factors defined by a 'winged helix' DNA-binding domain. In this study we aimed to identify Fox factors that are expressed within the fat body of the yellow fever mosquito Aedes aegypti, and determine whether any of these are involved in the regulation of mosquito yolk protein gene expression ...
Immo A. Hansen +7 more
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Deciphering the role of forkhead transcription factors in cancer therapy. [PDF]
Curr Drug Targets, 2011 Forkhead O transcription factors (FOXO) are critical for the regulation of cell cycle arrest, cell death, and DNA damage repair. Inactivation of FOXO proteins may be associated with tumorigenesis, including breast cancer, prostate cancer, glioblastoma, rhabdomyosarcoma, and leukemia. Accumulated evidence shows that activation of oncogenic pathways such
Yang JY, Hung MC.
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Forkhead transcription factors and ageing [PDF]
Oncogene, 2008 Mutations in single genes and environmental interventions can extend healthy lifespan in laboratory model organisms. Some of the mechanisms involved show evolutionary conservation, opening the way to using simpler invertebrates to understand human ageing.
Linda Partridge, Jens C. Brüning
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Forkhead transcription factors in ovarian function [PDF]
REPRODUCTION, 2011 Since the discovery of the conserved forkhead (Fkh) DNA binding domain more than 20 years ago, members of the Fkh or forkhead box (FOX) family of transcription factors have been shown to act as important regulators of numerous developmental and homeostatic processes.
Mathias Treier, Nina Henriette Uhlenhaut
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The Forkhead Transcription Factor FoxC2 Inhibits White Adipocyte Differentiation [PDF]
Journal of Biological Chemistry, 2004 In this study, we show that expression of FoxC2 blocks the capacity of 3T3-L1 preadipocytes to undergo adipogenesis in the presence of dexamethasone, isobutylmethylxanthine, and insulin. This block is characterized by an extensive decrease in the expression of proteins associated with the function of the mature fat cell, most notably C/EBPalpha ...
Kathryn E. Davis +2 more
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