Results 21 to 30 of about 626,933 (316)

Unified nomenclature for the winged helix/forkhead transcription factors. [PDF]

Genes & Development, 2000
The winged helix/forkhead class of transcription factors is characterized by a 100-amino-acid, monomeric DNAbinding domain. The structure of the DNA-binding domain of one of the class members, hepatocyte nuclear factor 3 g (HNF3g), in a complex with a ...
K. Kaestner, W. Knöchel, D. Martinez
semanticscholar   +3 more sources

The yeast forkhead transcription factors fkh1 and fkh2 regulate lifespan and stress response together with the anaphase-promoting complex. [PDF]

PLoS Genetics, 2012
Forkhead box O (FOXO) transcription factors have a conserved function in regulating metazoan lifespan. A key function in this process involves the regulation of the cell cycle and stress responses including free radical scavenging.
Spike D L Postnikoff, Mackenzie E Malo, Berchman Wong, Troy A A Harkness   +3 more
doaj   +2 more sources

Forkhead Transcription Factors: Formulating a FOXO Target for Cognitive Loss. [PDF]

Curr Neurovasc Res, 2017
K. Maiese
semanticscholar   +2 more sources

Novel Treatment Strategies for the Nervous System: Circadian Clock Genes, Non-coding RNAs, and Forkhead Transcription Factors. [PDF]

Curr Neurovasc Res, 2018
K. Maiese
semanticscholar   +2 more sources

Role of forkhead transcription factors in endocrine sensitive and resistant breast cancer cell lines

, 2010
Breast cancer is a major concern worldwide as it accounts for one of the highest causes of death. Oestrogen which is widely known for its growth-promoting function in mammary gland has been linked to breast cancer pathogenesis.
Sivanandan, Kavitta, Sivanandan, Kavitta
core   +3 more sources

The putative forkhead transcription factor FhpA is necessary for development, aflatoxin production, and stress response in Aspergillus flavus.

PLoS ONE
Forkhead transcription factors regulate several important biological processes in many eukaryotic species including fungi. Bioinformatic analysis of the Aspergillus flavus genome revealed four putative forkhead transcription factor genes.
Jessica M Lohmar, Stephanie R Gross, Carol H Carter-Wientjes, Brian M Mack, Qijian Wei, Matthew D Lebar, Jeffrey W Cary   +6 more
doaj   +3 more sources

Advances in the study of FOXQ1: biological functions and mechanisms [PDF]

Frontiers in Oncology
Forkhead box Q1 (FOXQ1) is a member of the Forkhead box gene family and an important transcription factor closely associated with several human diseases, especially tumorigenesis and tumor progression. This review aims to explore advances in the study of
Xiaojian Feng, Ling Zhang, Peiyao Shi, Yiping Hu, Yiping Hu, Yiping Hu   +5 more
doaj   +2 more sources

Propofol postconditioning ameliorates hypoxia/reoxygenation induced H9c2 cell apoptosis and autophagy via upregulating forkhead transcription factors under hyperglycemia [PDF]

Mil Med Res, 2021
Ronghui Han, Hemeng Huang, Hong Han, Hao Chen, Fei Zeng, Xiang Xie, Danyong Liu, Yin Cai, Liang-Qing Zhang, Xin Liu, Zhengyuan Xia, Jing Tang   +11 more
openalex   +2 more sources

Fox tales: Regulation of gonadotropin gene expression by forkhead transcription factors [PDF]

Mol Cell Endocrinol, 2014
V. Thackray
semanticscholar   +2 more sources

Mammalian SIRT1 Represses Forkhead Transcription Factors [PDF]

Cell, 2004
The NAD-dependent deacetylase SIR2 and the forkhead transcription factor DAF-16 regulate lifespan in model organisms, such as yeast and C. elegans. Here we show that the mammalian SIR2 ortholog SIRT1 deacetylates and represses the activity of the forkhead transcription factor Foxo3a and other mammalian forkhead factors. This regulation appears to be in
Maria Carla Motta, N. Divecha, M. Lemieux, C. Kamel, Delin Chen, W. Gu, Yvette Bultsma, M. McBurney, L. Guarente   +8 more
semanticscholar   +5 more sources