Foscarnet-induced penile ulcer in a patient with cytomegalovirus coinfection refractory to ganciclovir and Clostridioides difficile: A case report [PDF]
IDCasesCoinfections by cytomegalovirus and Clostridioides difficile are rare and can be life-threatening, especially in immunosuppressed patients. Their symptoms often overlap, thus generating a great diagnostic challenge, with the need for multiple diagnostic ...
John Jairo Cardeño-Sánchez +3 more
doaj +2 more sources
Reversion of Val(Ganciclovir)-Resistance-Associated Mutations in Two SOT Patients with Mismatched Serostatus for CMV (D+/R-) [PDF]
VirusesThe emergence of drug-resistant cytomegalovirus (CMV) complicates viral response to therapy. We present two cases of solid organ transplant (SOT) recipients, highlighting the reversion of UL97 mutations associated with val(ganciclovir) resistance ...
Elena Seminari +9 more
doaj +2 more sources
CMV Preventive and Treatment Studies in Children Undergoing Haematopoietic Stem Cell Transplant: A Systematic Review. [PDF]
Rev Med VirolABSTRACT Cytomegalovirus (CMV) is one of the most important infectious causes of morbidity and mortality in children undergoing haematopoietic stem cell transplant (HSCT). However, the evidence for preventing and treating CMV disease in children in this context remains limited. We sought to review the current available evidence regarding the prevention
Fusani L +7 more
europepmc +2 more sources
Characteristics of Acyclovir-Resistant Herpes Simplex Virus Infection in Hematological Patients. [PDF]
J Oral Pathol MedABSTRACT Objective Acyclovir‐resistant herpes simplex virus infections pose a significant challenge in immunosuppressed patients. This study aimed to characterize the clinical features, treatment outcomes, and mortality associated with acyclovir‐resistant herpes simplex virus infection. Materials and Methods A retrospective analysis was conducted on 18
Shehadeh R +7 more
europepmc +2 more sources
Transplantation and Cellular Therapy, 2023 BACKGROUND Human herpesvirus 6 (HHV-6) reactivation is common after allogeneic hematopoietic stem cell transplantation (allo-HSCT) and is associated with higher mortality and transplant-related complications.
Pongthep Vittayawacharin +9 more
semanticscholar +1 more source
Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review. [PDF]
Clin Pharmacol TherLimited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Alatawi W +6 more
europepmc +2 more sources
Treatment of gastroparesis with botulinum toxin in patient after allogenic bone marrow transplantation [PDF]
Терапевтический архив, 2018 The case report of botulinum toxin treatment of gastroparesis in a patient following allogenic bone marrow transplantation is described. The causes of gastroparesis and methods of prevention and treatment are discussed.
G.M. GALSTYAN +6 more
doaj +2 more sources
Resistance to antiviral drugs in human viruses from the subfamily Betaherpesvirinae
Вопросы вирусологии, 2022 The review provides information on the mechanisms of the emergence of resistance to antiviral drugs in human viruses from the subfamily Betaherpesvirinae. Data on the principles of action of antiviral drugs and their characteristics are given.
Mikhail V. Demin +3 more
doaj +1 more source
Clinical Transplantation, 2021 Letermovir (LTV) might be an alternative treatment to nephrotoxic foscarnet (FOS) in Ganciclovir (GCV) resistant cytomegalovirus (CMV) infection.
E. Rho +5 more
semanticscholar +1 more source
Anti-N-methyl-D-aspartate receptor encephalitis 8 years after serial herpes simplex virus type 1 and human herpesvirus type 7 encephalitis [PDF]
Encephalitis, 2021 Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is triggered by herpesvirus encephalitis. Human herpesvirus type 7 (HHV-7) is a recently described herpesvirus for which neuroinvasion has been reported rarely.
Yoonhyuk Jang +7 more
doaj +1 more source