In vitro susceptibility of six isolates of equine herpesvirus 1 to acyclovir, ganciclovir, cidofovir, adefovir, PMEDAP and foscarnet [PDF]
, 2007 International ...
Croubels, Siska +6 more
core +3 more sources
Biology of Blood and Marrow Transplantation, 2020 Despite a well-established risk of chronic kidney disease (CKD) after allogeneic hematopoietic cell transplant (AlloHCT), the benefits of using nephrotoxic anti-infective agents to treat serious peri-transplant infections often outweigh this risk.
Gena G. Foster +8 more
semanticscholar +1 more source
A randomized, controlled trial comparing ganciclovir to ganciclovir plus foscarnet (each at half dose) for preemptive therapy of cytomegalovirus infection in transplant recipients [PDF]
, 2004 Forty-eight patients who provided 2 consecutive blood samples that tested positive for cytomegalovirus DNA by polymerase chain reaction (PCR) were randomized to receive either full-dose ganciclovir ( 5 mg/kg intravenously [iv] twice daily) or half-dose ...
Amooty, G +15 more
core +1 more source
Variability in antifungal and antiviral use in hospitalized children [PDF]
, 2017 We analyzed antifungal and antiviral prescribing among high-risk children across freestanding children’s hospitals. Antifungal and antiviral days of therapy varied across hospitals.
Gerber, Jeffrey S +6 more
core +2 more sources
Antimicrobial Agents and Chemotherapy, 2020 Herein, we phenotypically and enzymatically characterize the theoretical mutation Q579I in helix K and the already described clinical mutation K805Q in helix P of cytomegalovirus DNA polymerase for susceptibility to foscarnet. Q579I and K805Q recombinant
Karima Zarrouk +4 more
semanticscholar +1 more source
The Role of Nucleotide Excision by Reverse Transcriptase in HIV Drug Resistance
Viruses, 2010 Nucleoside reverse transcriptase (RT) inhibitors of HIV block viral replication through the ability of HIV RT to incorporate chain-terminating nucleotide analogs during viral DNA synthesis. Once incorporated, the chain-terminating residue must be removed
Walter A. Scott, Antonio J. Acosta-Hoyos
doaj +1 more source
Impact of IFN lambda 3/4 single nucleotide polymorphisms on the cytomegalovirus reactivation in autologous stem cell transplant patients [PDF]
, 2018 Cytomegalovirus (CMV) infection represents one of the main cause mortality after Stem Cell Transplantation. Recently, a protective effect of the T allele of rs12979860 IL28B Single Nucleotide Polymorphisms (SNPs) against CMV infection in the allogenic ...
Angeletti, S +13 more
core +1 more source
Antiviral Resistance in Human Cytomegalovirus Due to UL54 Mutations Without UL97 Mutations
Annals of Clinical Microbiology, 2022 Background: The concurrent detection of human cytomegalovirus (CMV) with UL97 and UL54 mutations is crucial for prescribing adequate antiviral treatment when drug-resistant CMV infection is suspected.
Kuenyoul Park +4 more
doaj +1 more source
Treatment of cytomegalovirus retinitis with an intraocular sustained-release ganciclovir implant [PDF]
, 2000 The objective of this prospective study was to evaluate the efficacy and complications of the use of an intraocular sustained-release ganciclovir implant for the treatment of active cytomegalovirus (CMV) retinitis in AIDS patients. Thirty-nine eyes of 26
Belfort, Rubens Junior +1 more
core +3 more sources
Biology of Blood and Marrow Transplantation, 2018 Cord blood transplantation (CBT) is a distinct risk factor for human herpesvirus-6 (HHV-6) reactivation and HHV-6 encephalitis. In a prospective multicenter trial we investigated the effects of prophylactic foscarnet (90 mg/kg i.v.
M. Ogata +18 more
semanticscholar +1 more source