Results 71 to 80 of about 3,264,360 (304)

Social contagions on interdependent lattice networks [PDF]

, 2017
Although an increasing amount of research is being done on the dynamical processes on interdependent spatial networks, knowledge of how interdependent spatial networks influence the dynamics of social contagion in them is sparse.
Gao, Lei, Shu, Panpan, Stanley, Harry Eugene, Wang, Wei, Zhao, Pengcheng   +4 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

The development of pre-service teachers’ competence to teach mental calculation strategies

South African Journal of Childhood Education
Background: There is a concern in South Africa that pre-service teachers do not have the required knowledge to teach mathematics in primary school and to develop learners’ number sense.
Pamela Vale, Lise Westaway
doaj   +1 more source

Evaluating the Foundation Phase: technical report [PDF]

, 2016
In this report we present a technical discussion of the three year evaluation (August 2011 to August 2014). This includes an outline of the evaluation design, the methods used in the evaluation and other detailed information about the evaluation.
Taylor, Christopher Matthew, Maynard, Trisha, Davies, Owen Rhys, Waldron, Sam, Rhys, Mirain, Power, Sally A.R., Moore, Laurence Anthony Russell, Blackaby, David, Plewis, Ian   +8 more
openaire  

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Optimization of crystal nucleation close to a metastable fluid-fluid phase transition [PDF]

, 2015
The presence of a metastable fluid-fluid critical point is thought to dramatically influence the crystallization pathway, increasing the nucleation rate by many orders of magnitude over the predictions of classical nucleation theory.
Buldyrev, Sergey V., Franzese, Giancarlo, Reguera, David, Stanley, Harry Eugene, Wedekind, Jan, Xu, Limei   +5 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Neural Control of Rhythmic Coordinated Movements [PDF]

, 1994
How do humans and other animals accomplish coordinated movements? How are novel combinations of limb joints rapidly assembled into new behavioral units that move together in in-phase or anti-phase movement patterns during complex movement tasks? A neural
Cohen, Michael A., Grossberg, Stephen, Pribe, Christopher   +2 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Paul Hamlyn Foundation and Unbound Philanthropy Supported Options Initiative: Evaluation of Phase One [PDF]

, 2015
The Supported Options Initiative is one element of the Paul Hamlyn Foundation's Social Justice programme, delivered in partnership with Unbound Philanthropy (the Foundations). The first phase of the Initiative ran for two years from 2012.
Ben Cairns, Leila Baker, Ravi Kohli
core