Expression of Foxp3 in colorectal cancer but not in Treg cells correlates with disease progression in patients with colorectal cancer [PDF]
, 2013 Background: Regulatory T cells (Treg) expressing the transcription factor forkhead-box protein P3 (Foxp3) have been identified to counteract anti-tumor immune responses during tumor progression. Besides, Foxp3 presentation by cancer cells itself may also
A Ho-Pun-Cheung +45 more
core +17 more sources
The role of regulatory T cells in autoimmune thyroiditis
Медицинский совет, 2021 Autoimmune thyroiditis is an organ-specific autoimmune disease caused by the activation of self-reactive CD4+ T cells. Regulatory T (Treg) cells are a population of T cells that play a central role in immunological tolerance by suppressing selfreactive ...
S. I. Zhukova +4 more
doaj +1 more source
Journal of Respiration, 2023 Leukemia inhibitory factor (LIF), a member of the IL-6 cytokine family, is highly expressed throughout the body in multiple tissues and cell types. LIF is primarily known to induce the differentiation of myeloid leukemia cells, but recent studies show ...
Howard Yu +8 more
doaj +1 more source
Immunomodulatory Effect of Propolis on Foxp3 Gene Expression in Human Peripheral Blood Mononuclear Cells Stimulated in vitro with Pseudomonas Aeruginosa Ag [PDF]
Archives of Razi Institute, 2021 Immune balance during infection is critical for both supporting the defense of the immune system of the body and preventing an overly aggressive immune response.
F. A Alwaeely, K. N Madlum, M. A Alsaadi
doaj +1 more source
Upregulation of Cytotoxic T-Lymphocyte-Associated Protein 4 and Forkhead Box P3 Transcripts in Peripheral Blood of Patients with Bladder Cancer [PDF]
Iranian Journal of Medical Sciences, 2021 Background: Regulatory T cells (Tregs) play a key role in the progression of tumors. These cells express forkhead box P3 (FOXP3) and cytotoxic T-lymphocyte-associated protein 4 (CTLA4), which are the potential targets for cancer immunotherapy.
Ali Ariafar +7 more
doaj +1 more source
Impact of breast milk miR-155 on the health of preterm neonates
Zdorovʹe Rebenka, 2022 Background. Breast milk (BM) is an important source of microRNAs (miRs). MicroRNAs are highly resistant to gastrointestinal enzymes and are well absorbed in the intestine. MiR-155 is one of the most expressed miR of BM.
O.E. Abaturov, A.O. Tovarnytska
doaj +1 more source
Медицинская иммунология, 2023 T regulatory lymphocytes (Treg) are present is adipose tissue. Their frequency, as well as the level of FoxP3 nuclear translocation, in epicardial and thymus adipose tissue remains unexplored.
I. V. Kologrivova +6 more
doaj +1 more source
A2 adenosine receptor contributes to the development of cow’s milk protein allergy via regulating regulatory T cells [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): A2 adenosine receptor (A2AR) is a novel promising target for the treatment of inflammatory and allergic diseases. However, its role in the development of cow’s milk protein allergy (CMPA) has not been elucidated.
Chuan-Ying Li +4 more
doaj +1 more source
Siah2 control of T-regulatory cells limits anti-tumor immunity. [PDF]
, 2020 Understanding the mechanisms underlying anti-tumor immunity is pivotal for improving immune-based cancer therapies. Here, we report that growth of BRAF-mutant melanoma cells is inhibited, up to complete rejection, in Siah2-/- mice.
Aifantis, Ioannis +15 more
core +2 more sources
Plasmodium yoelii infection of BALB/c mice results in expansion rather than induction of CD4+ Foxp3+ regulatory T cells [PDF]
, 2016 Recently, we demonstrated elevated numbers of CD4(+) Foxp3(+) regulatory T (Treg) cells in Plasmodium yoelii‐infected mice contributing to the regulation of anti‐malarial immune response. However, it remains unclear whether this increase in Treg cells is
Abel, S. +9 more
core +1 more source