Results 1 to 10 of about 171,978 (359)

Upregulation of Cytotoxic T-Lymphocyte-Associated Protein 4 and Forkhead Box P3 Transcripts in Peripheral Blood of Patients with Bladder Cancer [PDF]

Iranian Journal of Medical Sciences, 2021
Background: Regulatory T cells (Tregs) play a key role in the progression of tumors. These cells express forkhead box P3 (FOXP3) and cytotoxic T-lymphocyte-associated protein 4 (CTLA4), which are the potential targets for cancer immunotherapy.
Ali Ariafar, Mojtaba Habibagahi, Mansooreh Jaberipour, Abdolaziz Khezri, Mohammad Hadi Khezri, Hale Bozorgi, Ahmad Hosseini, Mahboobeh Razmkhah   +7 more
doaj   +1 more source

Expression of Foxp3 in colorectal cancer but not in Treg cells correlates with disease progression in patients with colorectal cancer [PDF]

, 2013
Background: Regulatory T cells (Treg) expressing the transcription factor forkhead-box protein P3 (Foxp3) have been identified to counteract anti-tumor immune responses during tumor progression. Besides, Foxp3 presentation by cancer cells itself may also
A Ho-Pun-Cheung, A Merlo, Ana Maria Waaga-Gasser, Andreas Rosenwald, C Loddenkemper, Christoph-Thomas Germer, E Sato, Eva Meier, F Ichihara, FA Sinicrope, FL Greene, H Groux, H Lu, H Suzuki, H Tao, HL Weiner, Igor Tsaur, J Shimizu, JD Fontenot, Jun Li, LM Ebert, M Viguier, Maria Lazariotou, Martin Gasser, Martin Grimm, ME Winerdal, Mia Kim, MJ Sack, N Chaput, N Hiraoka, N Kobayashi, P Correale, P Salama, P Yu, Roman Blaheta, S Hinz, S Ladoire, S Onizuka, T Alvaro, Tanja Grimmig, TL Whiteside, Uwe Heemann, V Karanikas, W Zou, WH Wang, WS Lee   +45 more
core   +18 more sources

Immunomodulatory Effect of Propolis on Foxp3 Gene Expression in Human Peripheral Blood Mononuclear Cells Stimulated in vitro with Pseudomonas Aeruginosa Ag [PDF]

Archives of Razi Institute, 2021
Immune balance during infection is critical for both supporting the defense of the immune system of the body and preventing an overly aggressive immune response.
F. A Alwaeely, K. N Madlum, M. A Alsaadi
doaj   +1 more source

Regulatory T cells (Tregs) and their therapeutic potential against autoimmune disorders – Advances and challenges

Human Vaccines & Immunotherapeutics, 2022
Autoimmune diseases are caused when immune cells act against self-protein. This biological self–non-self-discrimination phenomenon is controlled by a distinct group of lymphocytes known as regulatory T cells (Tregs), which are key inflammatory response ...
Tapas Kumar Goswami, Mithilesh Singh, Manish Dhawan, Saikat Mitra, Talha Bin Emran, Ali A. Rabaan, Abbas Al Mutair, Zainab Al Alawi, Saad Alhumaid, Kuldeep Dhama   +9 more
doaj   +1 more source

Characterization of human epithelial resident memory regulatory T cells

Frontiers in Immunology, 2022
Human resident memory regulatory T cells (Tregs) exist in the normal, noninflamed skin. Except one, all previous studies analyzed skin Tregs using full-thickness human skin.
Takuya Sato, Youichi Ogawa, Kazunori Yokoi, Yuka Nagasaka, Aoha Ishikawa, Ichiro Shiokawa, Manao Kinoshita, Rei Watanabe, Shinji Shimada, Atsushi Tanaka, Akira Momosawa, Tatsuyoshi Kawamura   +11 more
doaj   +1 more source

Prediction of response to surgical therapy in nonsegmental vitiligo based on an immunohistochemical cutoff value

Journal of the Egyptian Women’s Dermatologic Society, 2020
Background Objective assessment of stability is still lacking in nonsegmental vitiligo (NSV). Objective To suggest immunohistochemical cutoff values that can predict a good response to surgical therapy of NSV cases.
Dalia A Bassiouny, Samar El Tahlawy, Amira El Tawdy, Mostafa Abdellatif, Doaa Ibrahim Eldesouky Amin   +4 more
doaj   +1 more source

A2 adenosine receptor contributes to the development of cow’s milk protein allergy via regulating regulatory T cells [PDF]

Iranian Journal of Basic Medical Sciences, 2021
Objective(s): A2 adenosine receptor (A2AR) is a novel promising target for the treatment of inflammatory and allergic diseases. However, its role in the development of cow’s milk protein allergy (CMPA) has not been elucidated.
Chuan-Ying Li, Zhen Qin, ShaoHua Mei, Yan Hu, Cheng Wu   +4 more
doaj   +1 more source

The Role of Leukemia Inhibitory Factor in Counteracting the Immunopathology of Acute and Chronic Lung Inflammatory Diseases

Journal of Respiration, 2023
Leukemia inhibitory factor (LIF), a member of the IL-6 cytokine family, is highly expressed throughout the body in multiple tissues and cell types. LIF is primarily known to induce the differentiation of myeloid leukemia cells, but recent studies show ...
Howard Yu, Sahil Zaveri, Meshach Pillai, Harsha Taluru, Michael Schaible, Sahil Chaddha, Asad Ahmed, Said Tfaili, Patrick Geraghty   +8 more
doaj   +1 more source

Impact of breast milk miR-155 on the health of preterm neonates

Zdorovʹe Rebenka, 2022
Background. Breast milk (BM) is an important source of microRNAs (miRs). MicroRNAs are highly resistant to gastrointestinal enzymes and are well absorbed in the intestine. MiR-155 is one of the most expressed miR of BM.
O.E. Abaturov, A.O. Tovarnytska
doaj   +1 more source

Relationship between vitamin D plasma level and Foxp3 gene expression among rheumatoid arthritis patients

مجله علمی دانشگاه علوم پزشکی کردستان, 2018
Background and Aim: Rheumatoid arthritis (RA) is an autoimmune disease. It seems that the function of regulatory T cells (Tregs) is compromised in RA. Foxp3 is a critical transcription factor of these cells.
Zafari P, Mostafaei Sh, Iranshahi N, Jalili C, Taghadosi M   +4 more
doaj   +1 more source