Results 271 to 280 of about 171,978 (359)

Low-Intensity Pulsed Ultrasound Promotes a Treg-Like Phenotype and Suppresses a Th17-Like Phenotype in CD4⁺ T Cells via YAP/TAZ Activation in vitro. [PDF]

J Inflamm Res
Yang R, Zhang X, Zhang Y, Man Y, Yang X.
europepmc   +1 more source

Single‐Cell RNA Sequencing Identifies Accumulation of Fcgr2b + Virtual Memory‐Like CD8 T Cells With Cytotoxic and Inflammatory Potential in Aged Mouse White Adipose Tissue

Aging Cell, EarlyView.
Age‐associated accumulation of Fcgr2b + VM‐like CD8 T cells within visceral adipose tissue contributes to inflammation. ABSTRACT Aging and obesity are associated with pro‐inflammatory changes in adipose tissue. Overlapping mechanisms, such as the infiltration of inflammatory macrophages and T cells into visceral adipose tissue, have been implicated in ...
Archit Kumar, Martin O'Brien, Vincent B. Young, Raymond Yung   +3 more
wiley   +1 more source

Peptides Derived from α-Tubulin Induce Functional T Regulatory Cells. [PDF]

Int J Mol Sci
Fiyouzi T, Subiza JL, Lafuente EM, Reche PA.   +3 more
europepmc   +1 more source

Modulation of Cellular, Molecular, and Humoral Responses by PQ Grass 27,600 SU for the Treatment of Seasonal Allergic Rhinitis: A Randomised Double Blind Placebo Control Exploratory Field Study

Allergy, EarlyView.
The aim of the study is to interrogate immunological mechanisms induced by PQ Grass conventional and extended regimens. A short‐course pre‐seasonal subcutaneous injection of PQ Grass is effective in inducing immune tolerance by generating functional blocking antibodies and modulating T cell compartments.
Janice A. Layhadi, Sviatlana Starchenka, Pieter‐Jan De Kam, Elizabeth Palmer, Lily Y. D. Wu, Sean T. Keane, William T. Fulton, Prista Hikmawati, Xun Meng, Paulina Filipaviciute, Anna Cutrina Pons, Kemi Oluwayi, Katarzyna Lis, Oliver Armfield, Murray A. Skinner, Matthew D. Heath, Simon J. Hewings, Matthias F. Kramer, Mohamed H. Shamji   +18 more
wiley   +1 more source

Regulatory T Cells in Invasive Breast Cancer: Prognosis, Mechanisms and Therapy. [PDF]

Cancers (Basel)
Xu A, Ayoub S, Zhang H, Wu Y, Rau M, Ma X.   +5 more
europepmc   +1 more source

Myeloid cAMP Reduction Shifts Rhinovirus‐Induced Airway Inflammation From Neutrophilic to Eosinophilic by Suppressing M1‐Interstitial Macrophages

Allergy, EarlyView.
ABSTRACT Background Asthma exacerbations caused by human rhinovirus (hRV) infection are characterized by airway neutrophilia and reduced corticosteroid response, leading to significant healthcare costs and lung function impairment. The Gαs subunit of the trimeric G protein regulates immunopathological conditions by modulating cAMP levels.
Seong Ok Park, Erdenebileg Uyangaa, Hyo Jin Kim, Hee Won Byeon, Jin Young Choi, Koanhoi Kim, Jihyung Lee, Samuel Bertin, Eyal Raz, Seong Kug Eo   +9 more
wiley   +1 more source

Focal adhesion kinase plays an essential role in Th17 cell differentiation by stimulating NF-κB signaling. [PDF]

Front Immunol
Kim HS, Lee JH, Sohn H, Lee WH, Kim GE, Lee W, Kim HR, Lee GR.   +7 more
europepmc   +1 more source

Obesity Impairs Skin Barrier Function and Facilitates Allergic Sensitization in Mice

Allergy, EarlyView.
Diet‐induced obesity increases transepidermal water loss and compromises barrier function through downregulation of tight junctions and desmosomes. During obesity, MC903 elicits a mixed Th1/2/17 immune response in the skin leading to aggravated ear swelling.
Alicia Martinek, Andrea Deinzer, Roman G. Gerlach, Jana Petzold, Lea Semmler, Christof Vorsatz, Padraic G. Fallon, Christian Schwartz   +7 more
wiley   +1 more source

Th17/Treg imbalance in inflammatory bowel disease: immunological mechanisms and microbiota-driven regulation. [PDF]

Front Immunol
Hu Y, Yang Y, Li Y, Zhang Q, Zhang W, Jia J, Han Z, Wang J.   +7 more
europepmc   +1 more source

Foxp3-Transduced Polyclonal Regulatory T Cells Protect against Chronic Renal Injury from Adriamycin

, 2006
Yuan Min Wang, Geoff Yu Zhang, Yiping Wang, Min Hu, Huiling Wu, Debbie Watson, Shohei Hori, Ian E. Alexander, David C.H. Harris, Stephen I. Alexander   +9 more
openalex   +1 more source