Results 271 to 280 of about 106,447 (316)

Protection Against Type 1 Diabetes Development in Mice With 4E-BP2 Deletion. [PDF]

Diabetes
Pita-Grisanti V, Peçanha FLM, Louzada RA, Blandino-Rosano M, Jaramillo C, Arenas N, Bayer A, Bernal-Mizrachi E.   +7 more
europepmc   +1 more source

Expression of FoxP3 in oral squamous cell carcinoma and its biological significance. [PDF]

Discov Oncol
Jiang L, Zhang Y, Zhu C, Song L, Ma Z, Liu H, Su Z, Xia M, Li J.   +8 more
europepmc   +1 more source

Tumor Infiltrating Lymphocytes in Cutaneous Squamous Cell Carcinoma-A Systematic Review. [PDF]

Dermatopathology (Basel)
Loo LY, Tay SH, Oh CC.
europepmc   +1 more source

FoxP3 Regulates T Follicular Regulatory Cell Function

, 2018
Shenda Hou
openalex   +1 more source

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Polymorphism of the ovine FOXP3 gene (FOXP3)

Veterinary Immunology and Immunopathology, 2011
FOXP3 is a transcription factor predominantly expressed in CD4(+) CD25(+) thymocytes and CD4(+) CD25(+) peripheral T cells. It has been reported that variation in the FOXP3 gene (FOXP3) could cause impaired immune regulation. Using PCR-SSCP, variation in exon 4, exon 9-10 and exon 13-14 of ovine FOXP3, covering three functional domains (a proline rich ...
Guo, Yang, Huitong, Zhou, Jon G H, Hickford   +2 more
openaire   +2 more sources

FoxP3 partners up

Nature Immunology, 2017
By switching its partners, FoxP3 segregates into functional and non-functional transcriptional complexes.
David Bending, Masahiro Ono
openaire   +2 more sources

Human FOXP3 and tumour microenvironment

Immunology, 2022
AbstractThe tumour microenvironment (TME) is a complex system composed of cancer cells, stromal cells and immune cells. Regulatory T cells (Tregs) in the TME impede immune surveillance of tumours and suppress antitumor immune responses. Transcription factor forkhead box protein 3 (FOXP3) is the main marker of Tregs, which dominates the function of ...
Jia Wang, Ruining Gong, Chenyang Zhao, Ke Lei, Xiaoyuan Sun, He Ren   +5 more
openaire   +2 more sources

Functional Analysis of FOXP3

Annals of the New York Academy of Sciences, 2008
Tolerance to self antigens is established in two ways: first in the thymus through the deletion of thymocytes expressing self‐reactive T cell receptors; and second, in the periphery through multiple mechanisms involving deletion, anergy, and suppression.
Jane H, Buckner, Steven F, Ziegler
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FOXP3+ regulatory T cells: control of FOXP3 expression by pharmacological agents

Trends in Pharmacological Sciences, 2011
Naturally arising CD4(+)CD25(+) regulatory T cells (Tregs), which specifically express the forkhead family transcription factor FOXP3, are essential for the maintenance of immunological self-tolerance and immune homeostasis. Tregs can suppress the activation, proliferation and effector function of other lymphocytes in physiological and pathological ...
Naganari, Ohkura, Masahide, Hamaguchi, Shimon, Sakaguchi   +2 more
openaire   +2 more sources