Results 111 to 120 of about 886 (145)

P125: Detection of pancreatic cancer in liquid biopsies using integrative fragmentomics

Genetics in Medicine Open
Dolev Rahat, Lilach Schneor, Noa Liscovitch-Brauer, Noam Shomron   +3 more
doaj   +1 more source

Liquid Biopsy in Gastrointestinal Cancers: Circulating Tumor DNA for Molecular Residual Disease Assessment and Early Treatment Monitoring. [PDF]

Cancers (Basel)
Safiejko K, Juchimiuk M, Pierko J, Maslyk M, Mucha M, Koda M, Konczuga-Koda L, Radej S, Akcakaya A, Szarpak L.   +9 more
europepmc   +1 more source

Genomics and Epigenomics Approaches for the Quantification of Circulating Tumor DNA in Liquid Biopsy: Relevance of a Multimodal Strategy. [PDF]

Int J Mol Sci
De Paolis E, Perrucci A, Albertini Petroni G, Conca A, Corsi M, Urbani A, Minucci A.   +6 more
europepmc   +1 more source

From multi-omics to deep learning: advances in cfDNA-based liquid biopsy for multi-cancer screening. [PDF]

Biomark Res
Luo X, Xie S, Hong F, Li X, Wei Y, Zhou Y, Su W, Yang Y, Tang L, Dao F, Cai P, Lin H, Lai H, Lyu H.   +13 more
europepmc   +1 more source

Dissecting cell-free DNA fragmentation variation in tumors using cell line-derived xenograft mouse. [PDF]

PLoS One
Fu R, Su HA, Zhao Y, Tian Y, Chen H, Lu D.   +5 more
europepmc   +1 more source

Circulating tumor DNA-guided early detection and minimal residual disease monitoring in pancreatic and biliary cancers: evidence, barriers, and opportunities. [PDF]

World J Surg Oncol
Liu R, Yang Y, Hu Z, Fu Y.
europepmc   +1 more source

Early detection of urological tumors based on genomic characteristics of cell-free DNA fragments: a multi-center study. [PDF]

NPJ Precis Oncol
Zhang H, Huang C, Wei C, Zhou R, Wang C, Lu W, Wang Z, Li X, Chen S, Wang D, Ji J, Li Y, Yang R, Chen J, Hu Y, Wang F.   +15 more
europepmc   +1 more source

Tumor-agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell-free DNA fragmentomics. [PDF]

Mol Oncol
Lapin M, Tjensvoll K, Edland KH, Oltedal S, Garresori H, Gilje B, Ekedal S, Eftestøl T, Kvaløy JT, Janku F, Nordgård O.   +10 more
europepmc   +1 more source

Cell-Free DNA Fragmentomics: The Novel Promising Biomarker

International Journal of Molecular Sciences, 2023
Cell-free DNA molecules are released into the plasma via apoptotic or necrotic events and active release mechanisms, which carry the genetic and epigenetic information of its origin tissues. However, cfDNA is the mixture of various cell fragments, and the efficient enrichment of cfDNA fragments with diagnostic value remains a great challenge for ...
Qinyu Ge, Min Pan, Yunfei Bai
exaly   +3 more sources