Results 101 to 110 of about 1,183 (178)

Protein-oligopeptide fragmentomics

, 2008
8
openaire   +2 more sources

A cfDNA fragmentomics-based liquid biopsy assay for early detection of oral cancer

Background Early detection of oral cancer improves outcomes, but remains limited by the invasiveness and low sensitivity of current screening methods. Methods
Tao Ding, Wei Yang, Maoxi Zhong, Peng He, Yuan Jiang, Cuicui Liu, Weiwei Wang, Xinyue Hong   +7 more
core   +1 more source

Genome-wide cfDNA fragmentation patterns in cerebrospinal fluid reflect medulloblastoma groups

npj Precision Oncology
Identifying molecular groups in medulloblastoma currently requires invasive biopsies for accurate diagnosis. We analyzed cerebrospinal fluid cell-free DNA (cfDNA) fragmentation patterns in 122 samples as a minimally-invasive alternative.
Alexander L Markowitz, Chetan Munugula, Eirini Christodoulou, Jianling Ji, Liya Xu, Jennifer A Cotter, Venkata Yellapantula   +6 more
doaj   +1 more source

A method of comprehensive sequencing analysis of the small RNA fragmentome (RiboMarker)

RNA
Circulating cell-free nucleic acids (cfDNA and cfRNA) found in blood and other biofluids are promising biomarkers for cancer. However, current methods exploiting tumor-derived cfDNA (ctDNA) are not sensitive enough in detecting minimal residual disease and early stages of cancer when it is more treatable.
Rachel C. Clark, Aidan C. Manning, Jonathan M. Howard, Sergio Barberán-Soler, Sergei A. Kazakov   +4 more
openaire   +2 more sources

Fragmentomics of plasma mitochondrial and nuclear DNA inform prognosis in COVID-19 patients with critical symptoms

Background The mortality rate of COVID-19 patients with critical symptoms is reported to be 40.5%. Early identification of patients with poor progression in the critical cohort is essential to timely clinical intervention and reduction of mortality ...
Fang Zheng, Xin Jin, Yeqin Wang, Wenwen Zhou, Rong Xie, Ye Tao, Jinjin Xu, Rijing Ou, Yilin Chen, Yu Lin, Yong Bai, Yuxue Luo, Haiqiang Zhang, Yan Zhang, Lingguo Li, Yan Jin, Ruokai Qu, Fanjun Cheng   +17 more
core   +1 more source

Cell-Free DNA Fragments as Biomarkers in Radiooncology and Gynecology [PDF]

Liquid biopsy of cell-free DNA (cfDNA) is a non-invasive diagnostic method that provides valuable biological insights into various diseases by analyzing DNA fragments released into the bloodstream.
Ivankovic, Ivna
core   +2 more sources

Systematic biases in reference-based plasma cell-free DNA fragmentomic profiling

Plasma cell-free DNA (cfDNA) fragmentation patterns are emerging directions in cancer liquid biopsy with high translational significance. Conventionally, the cfDNA sequencing reads are aligned to a reference genome to extract their fragmentomic features.
Pan, Yuqi, Lin, Huizhen, Hu, Dingxue, Wang, Wanqiu, Yang, Mengqi, Ju, Jia, Liu, Xiaoyi, An, Yunyun, Sun, Kun   +8 more
core   +1 more source

Piecing together pregnancy’s early warning system

cfDNA fragmentomics of routine prenatal screening data identifies adverse pregnancy outcomes in immune-mediated disease (Stanley et al. , this issue).
Nima Aghaeepour, Mohammad Amin Sadeghi
core   +1 more source

Detection and characterization of pancreatic and biliary tract cancers using cell-free DNA fragmentomics

Journal of Experimental & Clinical Cancer Research
Background Plasma cell-free DNA (cfDNA) fragmentomics has demonstrated significant differentiation power between cancer patients and healthy individuals, but little is known in pancreatic and biliary tract cancers.
Xiaohan Shi, Shiwei Guo, Qiaonan Duan, Wei Zhang, Suizhi Gao, Wei Jing, Guojuan Jiang, Xiangyu Kong, Penghao Li, Yikai Li, Chuanqi Teng, Xiaoya Xu, Sheng Chen, Baoning Nian, Zhikuan Li, Chaoliang Zhong, Xiaolu Yang, Guangyu Zhu, Yiqi Du, Dadong Zhang, Gang Jin   +20 more
doaj   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source