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Pathogenicity and virulence of Francisella tularensis [PDF]

open access: yesVirulence, 2023
Tularaemia is a zoonotic disease caused by the Gram-negative bacterium, Francisella tularensis. Depending on its entry route into the organism, F.
Manon Degabriel   +3 more
doaj   +2 more sources

Prosthetic joint infection as an unusual presentation of Francisella tularensis causing exposure of laboratory personnel [PDF]

open access: yesIDCases
Background: Infections with Francisella tularensis subsp. tularensis (type A) is highly virulent with mortality up to 30 % in untreated cases. Francisella tularensis subsp. holarctica (type B) is both less infectious and virulent.
Huma Aftab   +4 more
doaj   +2 more sources

Francisella tularensis subsp. holarctica bacteraemia in an immunocompetent male [PDF]

open access: yesRespiratory Medicine Case Reports, 2023
Tularemia is a rare zoonotic disease caused by the two predominant subspecies of Francisella tularensis, namely subspecies tularensis and subspecies holarctica.
Niels Schepens   +3 more
doaj   +2 more sources

Regulation of Francisella tularensis Virulence [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2011
Francisella tularensis is one of the most virulent bacteria known and a Centers for Disease Control and Prevention Category A select agent. It is able to infect a variety of animals and insects and can persist in the environment, thus Francisella spp ...
Shipan eDai   +7 more
doaj   +3 more sources

Amoebae can promote the survival of Francisella species in the aquatic environment

open access: yesEmerging Microbes and Infections, 2021
Francisella tularensis, a tier 1 select agent, is the causative bacterium of tularemia, a zoonosis with a large animal reservoir. However, F. tularensis, like many other Francisella species, is assumed to have an aquatic reservoir.
Aurélie Hennebique   +8 more
doaj   +1 more source

Identification of Francisella tularensis Subspecies in a Clinical Setting Using MALDI-TOF MS: An In-House Francisella Library and Biomarkers

open access: yesMicroorganisms, 2023
Francisella tularensis is a zoonotic bacterium that is endemic in large parts of the world. It is absent in the standard library of the most applied matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) systems: the ...
Maaike C. de Vries   +6 more
doaj   +1 more source

Presence of Francisella tularensis subsp. holarctica DNA in the Aquatic Environment in France

open access: yesMicroorganisms, 2021
In 2018, the incidence of tularemia increased twofold in the west of France, with many pneumonic forms, suggesting environmental sources of infection. We investigated the presence of Francisellatularensis subsp.
Camille D. Brunet   +5 more
doaj   +1 more source

Nlrp3 Increases the Host’s Susceptibility to Tularemia

open access: yesFrontiers in Microbiology, 2021
Francisella tularensis (F. tularensis) is a Gram-negative, intracellular bacterium and the causative agent of a fatal human disease known as tularemia. The CDC has classified F.
Ragavan V. Suresh   +7 more
doaj   +1 more source

Inguinal Ulceroglandular Tularemia Caused by Francisella tularensis Subspecies holarctica, Canada

open access: yesEmerging Infectious Diseases, 2021
Tularemia is a zoonotic disease caused by the gram-negative coccobacillus Francisella tularensis, a Biosafety Level 3 pathogen and potential agent of bioterrorism.
Carl Boodman   +6 more
doaj   +1 more source

Francisella tularensis subsp. tularensis induces a unique pulmonary inflammatory response: role of bacterial gene expression in temporal regulation of host defense responses. [PDF]

open access: yesPLoS ONE, 2013
Pulmonary exposure to Francisella tularensis is associated with severe lung pathology and a high mortality rate. The lack of induction of classical inflammatory mediators, including IL1-β and TNF-α, during early infection has led to the suggestion that F.
Kathie-Anne Walters   +8 more
doaj   +1 more source

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