Francisella tularensis,Portugal
To the Editor: Tularemia is a zoonosis caused by Francisella tularensis. Recently, tularemia has emerged in new locations, populations, and settings (1). After an outbreak in Spain in 1997 (2), it was expected that the disease would spread toward Portugal, a country with an extended area that borders the affected areas.
Isabel Lopes de Carvalho +5 more
openaire +3 more sources
Human tularemia in Italy. Is it a re-emerging disease? [PDF]
In order to evaluate whether tularemia is re-emerging in Italy, data on mortality and morbidity (obtained by the National Institute of Statistics; ISTAT), Italian cases described in the scientific literature and data concerning hospitalizations for ...
A., Bella +4 more
core +1 more source
Regulation of virulence in Francisella tularensis by small non-coding RNAs [PDF]
Using a cDNA cloning and sequencing approach we have shown that Francisella tularensis expresses homologues of several small RNAs (sRNAs) that are well-conserved among diverse bacteria.
Alain Charbit +6 more
core +2 more sources
Immunobiological Properties of Francisella tularensis 15/10 Strain with Deleted recA Gene
Deletion of recA gene in Francisella tularensis 15/10 genome leads to the increase in its sensitivity to ultraviolet irradiation, reduction of the homologous recombination capacity, and a slight decline of virulence for mice.
A. A. Lapin +6 more
doaj +1 more source
Objective of the study is to assess diagnostic efficiency of PCR kits «Gen Francisella tularensis - REF» and «Gen Francisella tularensis - RGF», when performing analysis of biological samples from animals with experimental tularemia, as compared to other
A. M. Senichkina +3 more
doaj +1 more source
Density-Dependent Prevalence of Francisella tularensis in Fluctuating Vole Populations, Northwestern Spain [PDF]
Self Archiving; https://wwwnc.cdc.gov/eid/page/copyright-and-disclaimers J.J.L.L., F.M., and R.R.P. held official licenses for trapping wildlife in Spain. Capture permits were provided by the Dirección General del Medio Natural, Junta de Castilla y León.
Anda, Pedro +9 more
core +4 more sources
Uncovering the components of the Francisella tularensis virulence stealth strategy [PDF]
Over the last decade, studies on the virulence of the highly pathogenic intracellular bacterial pathogen Francisella tularensis have increased dramatically.
Faron, Matthew +3 more
core +2 more sources
Putting the Jigsaw Together - A Brief Insight Into the Tularemia
Tularemia is a debilitating febrile and potentially fatal zoonotic disease of humans and other vertebrates caused by the Gram-negative bacterium Francisella tularensis. The natural reservoirs are small rodents, hares, and possibly amoebas in water.
Kubelkova K., Macela A.
doaj +1 more source
TaqMan real-time PCR assays for single-nucleotide polymorphisms which identify Francisella tularensis and its subspecies and subpopulations. [PDF]
Francisella tularensis, the etiologic agent of tularemia and a Class A Select Agent, is divided into three subspecies and multiple subpopulations that differ in virulence and geographic distribution.
Dawn N Birdsell +8 more
doaj +1 more source
A human macrophage – hepatocyte co-culture model for comparative studies of infection and replication of Francisella tularensis LVS strain and subspecies holarctica and mediasiatica [PDF]
Detection of intracellular LPS in macrophage / hepatocyte co-cultures infected with LVS (open bars), spp. holarctica (grey filled bars) or spp. mediasiatica (black filled bars) and untreated control (hatched bars).
Alexander S. Mosig +5 more
core +3 more sources

