Molecular Investigation of Tularemia Outbreaks, Spain, 1997–2008 [PDF]
, 2014 Tularemia outbreaks occurred in northwestern Spain in 1997–1998 and 2007–2008 and affected >1,000 persons. We assessed isolates involved in these outbreaks by using pulsed-field gel electrophoresis with 2 restriction enzymes and multilocus variable ...
Allue +34 more
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Genetic Manipulation of Francisella Tularensis [PDF]
Frontiers in Microbiology, 2011 Francisella tularensis is a facultative intracellular pathogen that causes the disease tularemia. F. tularensis subsp. tularensis causes the most severe disease in humans and has been classified as a Category A select agent and potential bioweapon.
Zogaj, Xhavit, Klose, Karl E.
openaire +3 more sources
Non-vaccinal prophylaxis of tularemia
Frontiers in MicrobiologyTularemia is a re-emerging zoonosis in many endemic countries. It is caused by Francisella tularensis, a gram-negative bacterium and biological threat agent.
Max Maurin +11 more
doaj +1 more source
Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection [PDF]
, 2016 Lysosomal cathepsins regulate an exquisite range of biological functions, and their deregulation is associated with inflammatory, metabolic, and degenerative diseases in humans.
Gurung, Prajwal +9 more
core +1 more source
A Novel Stochastic Multi-Scale Model of Francisella tularensis Infection to Predict Risk of Infection in a Laboratory [PDF]
, 2018 We present a multi-scale model of the within-phagocyte, within-host and population-level infection dynamics of Francisella tularensis, which extends the mechanistic one proposed by Wood et al. (2014). Our multi-scale model incorporates key aspects of the
Carruthers, J +5 more
core +3 more sources
Rombencephalitis Caused by Francisella tularensis [PDF]
Journal of Clinical Microbiology, 2013 ABSTRACT Common presentations of tularemia include pneumonia and ulceroglandular, oropharyngeal, or typhoidal disease. Neuromeningeal involvement is extremely rare. We report a case of a severe rhombencephalitis due to Francisella tularensis .
Barbaz, Mathilde +7 more
openaire +3 more sources
Rapid dissemination of
BMC Microbiology, 2008 Background Francisella tularensis subsp. tularensis is classified as a Category A bioweapon that is capable of establishing a lethal infection in humans upon inhalation of very few organisms.
Jerabek Paul A +7 more
doaj +1 more source
Genetic Sequence Matching Using D4M Big Data Approaches
, 2014 Recent technological advances in Next Generation Sequencing tools have led to increasing speeds of DNA sample collection, preparation, and sequencing. One instrument can produce over 600 Gb of genetic sequence data in a single run.
Dodson, Stephanie +2 more
core +1 more source
Re-emergence of tularemia in Germany: Presence of
, 2008 Background Tularemia re-emerged in Germany starting in 2004 (with 39 human cases from 2004 to 2007) after over 40 years of only sporadic human infections. The reasons for this rise in case numbers are unknown as is the possible reservoir of the etiologic
A Johansson +22 more
core +2 more sources
Infection Risk From Humans and Animals in the Anatomy Laboratory: A Scoping Review
Clinical Anatomy, EarlyView.ABSTRACT Whole‐body dissection is a cornerstone of anatomy education. During and following the COVID‐19 pandemic, exposure to infectious agents and other risks of dissection were highlighted. To identify potential risks, one must have the data outlining these risks in specific situations.
Margaret A. McNulty, Elizabeth R. Agosto
wiley +1 more source