Results 51 to 60 of about 24,449 (253)

Comparative genomic characterization of Francisella tularensis strains belonging to low and high virulence subspecies.

PLoS Pathogens, 2009
Tularemia is a geographically widespread, severely debilitating, and occasionally lethal disease in humans. It is caused by infection by a gram-negative bacterium, Francisella tularensis.
Mia D Champion, Qiandong Zeng, Eli B Nix, Francis E Nano, Paul Keim, Chinnappa D Kodira, Mark Borowsky, Sarah Young, Michael Koehrsen, Reinhard Engels, Matthew Pearson, Clint Howarth, Lisa Larson, Jared White, Lucia Alvarado, Mats Forsman, Scott W Bearden, Anders Sjöstedt, Richard Titball, Stephen L Michell, Bruce Birren, James Galagan   +21 more
doaj   +1 more source

Francisella tularensis strain typing using multiple-locus, variable-number tandem repeat analysis [PDF]

, 2001
Francisella tularensis, the etiological agent of tularemia, is found throughout the Northern hemisphere. After analyzing the F. tularensis genomic sequence for potential variable-number tandem repeats (VNTRs), we developed a multilocus VNTR analysis ...
Abrams, Michelle, Farlow, Jason, Keim, Paul, Lytle, Michael, Smith, Kimothy L., Wong, Jane   +5 more
core   +2 more sources

Francisella tularensis Schu S4 lipopolysaccharide core sugar and o-antigen mutants are attenuated in a mouse model of tularemia [PDF]

, 2014
The virulence factors mediating Francisella pathogenesis are being investigated, with an emphasis on understanding how the organism evades innate immunity mechanisms.
Apicella, Michael A, Gibson, Bradford W, Jones, Bradley D, Lindemann, Stephen R, Meyerholz, David K, Post, Deborah M.B., Rasmussen, Jed A   +6 more
core   +2 more sources

Genome characterisation of the genus Francisella reveals insight into similar evolutionary paths in pathogens of mammals and fish

BMC Genomics, 2012
Background Prior to this study, relatively few strains of Francisella had been genome-sequenced. Previously published Francisella genome sequences were largely restricted to the zoonotic agent F. tularensis.
Sjödin Andreas, Svensson Kerstin, Öhrman Caroline, Ahlinder Jon, Lindgren Petter, Duodu Samuel, Johansson Anders, Colquhoun Duncan J, Larsson Pär, Forsman Mats   +9 more
doaj   +1 more source

Francisella and tularemia in western Asia, Iran: a systematic review

New Microbes and New Infections, 2023
Tularemia or rabbit fever is a transmissible disease from animals, rodents, and insects to human populations that is caused by Francisella tularensis. Epidemiological studies showed that tularemia is endemic throughout most different regions of the world.
Zahra Fooladfar, Farhad Moradi
doaj   +1 more source

A Full-Genomic Sequence-Verified Protein-Coding Gene Collection for Francisella tularensis [PDF]

, 2011
The rapid development of new technologies for the high throughput (HT) study of proteins has increased the demand for comprehensive plasmid clone resources that support protein expression.
Brizuela, Leonardo, Fernandez, Mauricio J., Hu, Yanhui, Jepson, Daniel Ashley, Kelley, Fontina, LaBaer, Joshua, McCarron, Seamus, Mohr, Stephanie, Moreira, Donna, Murthy, Tal, Petrosino, Joseph, Raphael, Jacob, Rolfs, Andreas, Shi, Zhenwei, Taycher, Elena, Zuo, Dongmei   +15 more
core   +1 more source

A short peptide derived from late embryogenesis abundant proteins enhances acid tolerance in Escherichia coli via modulation of two‐component regulatory systems

The FEBS Journal, Volume 293, Issue 3, Page 781-805, February 2026.
Expression of the LEA‐K peptide in E. coli BL21 (DE3) improved bacterial viability under acidic stress (pH4), suggesting a protective function. RNA‐sequencing of LEA‐K‐expressing vs. non‐expressing cells revealed 283 differentially expressed genes (DEGs). In silico docking linked LEA‐K to two‐component systems (TCS) proteins (Rcs, BtsS/R, and EnvZ/OmpR)
Khaled Metwally, Shinya Ikeno
wiley   +1 more source

Atomic Structure of IglD Demonstrates Its Role as a Component of the Baseplate Complex of the Francisella Type VI Secretion System

mBio, 2022
Francisella tularensis, a Tier 1 select agent of bioterrorism, contains a type VI secretion system (T6SS) encoded within the Francisella pathogenicity island (FPI), which is critical for its pathogenesis.
Xiaoyu Liu, Daniel L. Clemens, Bai-Yu Lee, Xue Yang, Z. Hong Zhou, Marcus A. Horwitz   +5 more
doaj   +1 more source

Különböző eredetű Francisella tularensis törzsek összehasonlító vizsgálata = Comparative examination of Francisella tularensis strains isolated from different species in Hungary [PDF]

, 2012
Vizsgálataink során Magyarország közel 30 településéről összesen 67 Francisella tularensis törzset gyűjtöttünk, amely révén létrehoztunk egy hazai F. tularensis törzsgyűjteményt.
Makrai, László
core  

Twin RNA Polymerase–associated Proteins Control Virulence Gene Expression in Francisella tularensis [PDF]

, 2012
The MglA protein is the only known regulator of virulence gene expression in Francisella tularensis, yet it is unclear how it functions. F. tularensis also contains an MglA-like protein called SspA.
Balon, Emmy, Boyd, Dana H., Charity, James Carl, Costante-Hamm, Michelle M, Dove, Simon L., Rubin, Eric Joseph, Schneewind, Olaf   +6 more
core   +1 more source