Results 71 to 80 of about 24,449 (253)
Эпидемиология и вакцинопрофилактика, 2018 Immunogenic properties of cell wall (CW) preparations of Francisella tularensis four subspecies are investigated. It is shown that the preparations from F. tularensis urea lysates are not toxic for experimental animals. Besides, CW of F.
A. V. Korneva +9 more
doaj +1 more source
Modified activities of macrophages’ deubiquitinating enzymes after Francisella infection
Frontiers in Immunology, 2023 Francisella tularensis influences several host molecular/signaling pathways during infection. Ubiquitination and deubiquitination are among the most important regulatory mechanisms and respectively occur through attachment or removal of the ubiquitin ...
Vera Vozandychova +8 more
doaj +1 more source
Inflammasomes: caspase-1-activating platforms with critical roles in host defense [PDF]
, 2011 Activation of the inflammatory cysteine protease caspase-1 in inflammasome complexes plays a critical role in the host response to microbial infections.
Lieselotte eVande Walle +3 more
core +2 more sources
Lethal Case of Bourbon Virus Leading to Shock and ECMO Utilization
Case Reports in Infectious Diseases, Volume 2026, Issue 1, 2026.We present a lethal case of Bourbon virus infection in a 63‐year‐old Caucasian, diabetic male who was previously in good health. The patient had spent time in the wooded areas of Bourbon County, Kansas, and removed three ticks from his body 5 days prior to presentation.
Allianna Mitchell +7 more
wiley +1 more source
Nutritional virulence of Francisella tularensis [PDF]
Frontiers in Cellular and Infection Microbiology, 2013 One of the mostfundamental aspects of infectious diseases is microbial acquisition of nutrients in vivo, which impacts virulence and antibiotic treatment.This article is focused on nutritional virulence of F.tularensis.
Šantić, Marina, Abu Kwaik, Yousef
openaire +4 more sources
Virulent Type A Francisella tularensis actively suppresses cytokine responses in human monocytes
Frontiers in Cellular and Infection Microbiology, 2014 Francisella tularensis is a Gram-negative facultative bacterium that can cause the disease tularemia, even upon exposure to low numbers of bacteria. One critical characteristic of Francisella is its ability to dampen or subvert the host immune response ...
Devyn D Gilette +10 more
doaj +1 more source
Border patrol gone awry: Lung NKT cell activation by Francisella tularensis exacerbates tularemia-like disease [PDF]
, 2015 The respiratory mucosa is a major site for pathogen invasion and, hence, a site requiring constant immune surveillance. The type I, semi-invariant natural killer T (NKT) cells are enriched within the lung vasculature.
Boyd, Kelli L +8 more
core +5 more sources
Emerging Infectious Diseases, 2022 Although Francisella tularensis is a well-known, highly virulent bacterium that causes tularemia in humans, other Francisella species have been associated with sporadic human infections. We describe a human cutaneous infection with bacteremia caused by F.
Aurélie Hennebique +9 more
doaj +1 more source
Extragenic suppressor mutations in ΔripA disrupt stability and function of LpxA [PDF]
, 2014 Background Francisella tularensis is a Gram-negative bacterium that infects hundreds of species including humans, and has evolved to grow efficiently within a plethora of cell types. RipA is a conserved membrane protein
Brunton, Jason C +10 more
core +1 more source
BMC Genomics, 2012 Background Francisella tularensis is an intracellular pathogen that causes tularemia in humans and the public health importance of this bacterium has been well documented in recent history. Francisella philomiragia, a distant relative of F.
Siddaramappa Shivakumara +4 more
doaj +1 more source