Results 51 to 60 of about 6,396,790 (306)

The Effects of Simvastatin on Free Fatty Acids Profile in Fructose-fed Insulin Resistant Rats [PDF]

Journal of Kerman University of Medical Sciences, 2018
Backgrounds: Type 2 diabetes mellitus is the most common metabolic disease and free fatty acids, as signaling molecules, can play a crucial role in the development of it.
Behnaz Danesh, Abbas Mohammadi, Hossein Fallah, Mostafa Allahyari   +3 more
doaj  

Microtitration of Free Fatty Acids in Plasma

Clinical Chemistry, 1967
Abstract A method for determination of free fatty acids in plasma has been developed which employs a modification of Dole's extraction procedure and involves a 1-phase system for titration rather than the 2-phase system most commonly used.
J E, Goss, A, Lein
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

The Effect of Temperature and Nitrate Compound on Growth, Biomass and Free Fatty Acid Content on Microalgae Culture of Spirulina sp. and Skeletonema sp.

Jurnal Bahan Alam Terbarukan, 2018
Temperature and availability nutrients played an important role on growth and lipid production of microalgae. In this study, we examined the effect of increasing suhu and excessed and depleted NO3 on growth rate, biomass and free fatty acid concentration
Nita Rukminasari, Muhammad Lukman, Rahmadi Tambaru, Dwi Fajriyati Inaku, Suharto Suharto   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Fatty acids and their metabolism critically regulate podocyte survival [PDF]

, 2014
Diabetic nephropathy (DN) is the most common cause of end-stage renal disease in industrialized countries, and most affected patients have type 2 diabetes.
Kampe, Kapil Dev
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Experimental investigation on DI diesel engine with fatty acid oil from by-product of vegetable oil refinery

Ain Shams Engineering Journal, 2019
This paper concerns about bio fuel production from renewable biomass resource and its characteristics in diesel engines. In this research work, Free Fatty Acid Oils (FFAO) from oil refineries was considered as biomass renewable resource for the ...
P. Deivajothi, V. Manieniyan, S. Sivaprakasam   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Effect of animal and industrial trans fatty acids on HDL and LDL cholesterol levels in humans - a quantitative review [PDF]

, 2010
Background: Trans fatty acids are produced either by industrial hydrogenation or by biohydrogenation in the rumens of cows and sheep. Industrial trans fatty acids lower HDL cholesterol, raise LDL cholesterol, and increase the risk of coronary heart ...
Wanders Anne J., Brouwer, I.A.; id_orcid, Martijn B. Katan, Katan Martijn B., Martijn B Katan, Ingeborg A Brouwer, Anne J. Wanders, Brouwer, I.A., Katan, M.B.; id_orcid, Katan, M.B., Anne J Wanders, Wanders, A.J., Ingeborg A. Brouwer, Brouwer Ingeborg A.   +13 more
core   +4 more sources