Results 51 to 60 of about 868,399 (309)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Arachidonic Acid as a Possible Negative Feedback Inhibitor of Nicotinic Acetylcholine Receptors on Neurons [PDF]

open access: yes, 1995
Neuronal acetylcholine receptors, being highly permeable to calcium, are likely to regulate calcium-dependent events in neurons. Arachidonic acid is a membrane-permeant second messenger that can be released from membrane phospholipids by phospholipases ...
Berg, Darwin K.   +3 more
core   +2 more sources

Experimental investigation on DI diesel engine with fatty acid oil from by-product of vegetable oil refinery

open access: yesAin Shams Engineering Journal, 2019
This paper concerns about bio fuel production from renewable biomass resource and its characteristics in diesel engines. In this research work, Free Fatty Acid Oils (FFAO) from oil refineries was considered as biomass renewable resource for the ...
P. Deivajothi   +2 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Deacidification of palm oil using solvent extraction integrated with membrane technology [PDF]

open access: yes, 2016
In this work, the efficiency of crude palm oil (CPO) deacidification using solvent extraction integrated with membrane technology is studied. Different solvents including ethanol, hexane and methanol were selected to extract the palmitic acid from model ...
Chong, K. C.   +3 more
core   +2 more sources

The Concentration of Polyunsaturated Fatty Acid in Palm Oil by Urea Complexation

open access: yesEquilibrium, 2018
Linoleic acid is a Poly-Unsaturated Fatty Acid (PUFA) that corresponds to Omega 6 Fatty Acid. This is the major component of vegetable oil and very important for health. As an essential fatty acid, linoleic acid has to be obtained from foods. Consumption
Dwi Ardiana Setyawardhani   +3 more
doaj   +1 more source

Genesis of Free Fatty Acids

open access: yesJournal of Investigative Dermatology, 1974
According In our current state of knowledge, free fatty acids are formed in sebaceous follicles primarily through hydrolysis of sebum triglycerides by microbial lipases. Because of their comedogenic and irritant qualities, these free fatty acids are probably responsible for many of the alterations in the follicle that result in acne lesions.
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Topical Formulation Comprising Fatty Acid Extract from Cod Liver Oil: Development, Evaluation and Stability Studies [PDF]

open access: yes, 2016
The purpose of this study was to develop a pharmaceutical formulation containing fatty acid extract rich in free omega-3 fatty acids such as eicosapentaenoic acid and docosahexaenoic acid for topical use. Although the health benefits of cod liver oil and
Hjálmarsdóttir, Martha Ásdís   +3 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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