Results 21 to 30 of about 61 (47)

The flexibility of SABRE, a new quantitative receptor function model, when fitting challenging concentration-effect data. [PDF]

Front Pharmacol
Olah B, Tarjanyi V, Takacs B, Pluzsnyik E, Viczjan G, Ovari I, Szilvassy Z, Juhasz B, Zsuga J, Erdei T, Gesztelyi R.   +10 more
europepmc   +1 more source

Commentary: The flexibility of SABRE, a new quantitative receptor function model, in fitting challenging concentration-effect data. [PDF]

Front Pharmacol
Buchwald P.
europepmc   +1 more source

Control of enteric neuromuscular functions by purinergic A(3) receptors in normal rat distal colon and experimental bowel inflammation. [PDF]

Br J Pharmacol, 2010
Antonioli L, Fornai M, Colucci R, Ghisu N, Tuccori M, Awwad O, Bin A, Zoppellaro C, Castagliuolo I, Gaion RM, Giron MC, Blandizzi C.   +11 more
europepmc   +1 more source

Advancing Covalent Ligand and Drug Discovery beyond Cysteine. [PDF]

Chem Rev
Kim G, Grams RJ, Hsu KL.
europepmc   +1 more source

Small Molecule, NSC95397, Inhibits the CtBP1-Protein Partner Interaction and CtBP1-Mediated Transcriptional Repression. [PDF]

J Biomol Screen, 2015
Blevins MA, Kouznetsova J, Krueger AB, King R, Griner LM, Hu X, Southall N, Marugan JJ, Zhang Q, Ferrer M, Zhao R.   +10 more
europepmc   +1 more source

Determination of adenosine A1 receptor agonist and antagonist pharmacology using Saccharomyces cerevisiae: implications for ligand screening and functional selectivity. [PDF]

J Pharmacol Exp Ther, 2009
Stewart GD, Valant C, Dowell SJ, Mijaljica D, Devenish RJ, Scammells PJ, Sexton PM, Christopoulos A.   +7 more
europepmc   +1 more source

A covalent antagonist for the human adenosine A_2A receptor. [PDF]

Purinergic Signal, 2017
Yang X, Dong G, Michiels TJM, Lenselink EB, Heitman L, Louvel J, IJzerman AP.   +6 more
europepmc   +1 more source

A cell-based PDE4 assay in 1536-well plate format for high-throughput screening. [PDF]

J Biomol Screen, 2008
Titus SA, Li X, Southall N, Lu J, Inglese J, Brasch M, Austin CP, Zheng W.   +7 more
europepmc   +1 more source

Inhibitors of the apurinic/apyrimidinic endonuclease 1 (APE1)/nucleophosmin (NPM1) interaction that display anti-tumor properties. [PDF]

Mol Carcinog, 2016
Poletto M, Malfatti MC, Dorjsuren D, Scognamiglio PL, Marasco D, Vascotto C, Jadhav A, Maloney DJ, Wilson DM, Simeonov A, Tell G.   +10 more
europepmc   +1 more source

Covalent Allosteric Probe for the Metabotropic Glutamate Receptor 2: Design, Synthesis, and Pharmacological Characterization. [PDF]

J Med Chem, 2019
Doornbos MLJ, Wang X, Vermond SC, Peeters L, Pérez-Benito L, Trabanco AA, Lavreysen H, Cid JM, Heitman LH, Tresadern G, IJzerman AP.   +10 more
europepmc   +1 more source