Results 71 to 80 of about 2,698 (202)

Fucoidan Characterization: Determination of Purity and Physicochemical and Chemical Properties

open access: yesMarine Drugs, 2020
Fucoidans are marine sulfated biopolysaccharides that have heterogenous and complicated chemical structures. Various sugar monomers, glycosidic linkages, molecular masses, branching sites, and sulfate ester pattern and content are involved within their ...
Ahmed Zayed   +3 more
doaj   +1 more source

Current strategies to enhance the target efficiency of advanced multifunctional ultrasound contrast agents in ischemic diseases

open access: yesInterdisciplinary Medicine, EarlyView.
The graphical abstract outlines a novel multifunctional ultrasound contrast agent for the diagnosis and treatment of ischemic diseases, along with innovative strategies to enhance its targeting efficiency. Abstract Ischemic diseases, such as myocardial infarction, stroke, and peripheral ischemia, are leading causes of death and disability worldwide ...
Yangyang Zhou   +3 more
wiley   +1 more source

Fucoidans from brown seaweeds:An update on structures, extraction techniques and use of enzymes as tools for structural elucidation [PDF]

open access: yes, 2013
Fucoidan or fucoidans cover a family of sulfated fucose-rich polysaccharides, built of a backbone of L-fucose units, and characteristically found in brown seaweeds.
Ale, Marcel Tutor, Meyer, Anne S.
core   +1 more source

Recent Advances in Cryogel Applications for Musculoskeletal Regeneration

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Hydrogels have been widely used in tissue engineering due to their high‐water content and biocompatibility, yet their densely cross‐linked microstructure inherently limits cell infiltration, mass transport, and mechanical support. Cryogels, formed through partial freezing and crosslinking under subzero conditions, provide unique 3D macroporous
Dohee Kim   +4 more
wiley   +1 more source

Characterization and Cytotoxic Activity of Microwave-Assisted Extracted Crude Fucoidans from Different Brown Seaweeds

open access: yes, 2023
Microwave-assisted extraction (MAE) is recognized as a green method for extraction of natural products. The current research aimed to explore the MAE for fucoidans extraction from different brown seaweeds, including Fucus vesiculosus, F.
Roland Ulber   +13 more
core   +1 more source

The Comparative Analysis of Antiviral Activity of Native and Modified Fucoidans from Brown Algae Fucus evanescens In Vitro and In Vivo

open access: yesMarine Drugs, 2020
The enzymatic depolymerization of fucoidans from brown algae allowed the production of their standardized derivatives with different biological activities.
Natalya V. Krylova   +10 more
doaj   +1 more source

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application

open access: yesPhytotherapy Research, EarlyView.
Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li   +14 more
wiley   +1 more source

Active pH Modulation by Proton Channel‐Peptide Nucleic Acid Complex for Effective siRNA Endosomal Escape

open access: yesSmall, EarlyView.
A bioinspired siRNA nanocarrier is engineered by integrating an influenza A M2 proton channel with siRNA through a peptide nucleic acid linker on liposome surfaces. Active proton transport amplifies osmotic stress within endosomes, triggering membrane rupture and cytosolic release.
Seongmin Ga   +16 more
wiley   +1 more source

Comparison of antioxidant potential in vitro, in cell cultivation and in vivo of commercially obtained fucoidans

open access: yes, 2021
Fucoidans are sulfated L-fucose-rich polysaccharides that are extracted from brown seaweed. These polymers are already commercially available and have been evaluated for various purposes. One of the most evaluated activities is the antioxidant, among the
Silva, Maylla Maria Correia Leite
core  

Impact of Positively Charged Backbone Modifications on the Properties of Spherical Nucleic Acids

open access: yesSmall, EarlyView.
A synthesis of spherical nucleic acids (SNAs) featuring cationic backbone modifications is presented, together with an analysis of their emerging properties. Introducing positively charged guanidinium groups near the SNA surface enhances cellular uptake and offers a pathway toward more precise control over SNA internalization.
Katherine E. Bujold   +4 more
wiley   +1 more source

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