Results 1 to 10 of about 911 (170)
Holothurian Fucosylated Chondroitin Sulfate [PDF]
Marine Drugs, 2014 Fucosylated chondroitin sulfate (FucCS) is a structurally distinct glycosaminoglycan found in sea cucumber species. It has the same backbone composition of alternating 4-linked glucuronic acid and 3-linked N-acetyl galactosamine residues within ...
Vitor H. Pomin
doaj +14 more sources
Chondroitin Sulfate and Fucosylated Chondroitin Sulfate as Stimulators of Hematopoiesis in Cyclophosphamide-Induced Mice [PDF]
Pharmaceuticals, 2021 The immunosuppression and inhibition of hematopoiesis are considered to be reasons for the development of complications after intensive chemotherapy and allogeneic hematopoietic stem cell transplantation.
Nadezhda E. Ustyuzhanina +11 more
doaj +3 more sources
(Semi)-Synthetic Fucosylated Chondroitin Sulfate Oligo- and Polysaccharides [PDF]
Marine Drugs, 2020 Fucosylated chondroitin sulfate (fCS) is a glycosaminoglycan (GAG) polysaccharide with a unique structure, displaying a backbone composed of alternating N-acetyl-d-galactosamine (GalNAc) and d-glucuronic acid (GlcA) units on which l-fucose (Fuc) branches
Giulia Vessella +4 more
doaj +5 more sources
Marine Drugs, 2020 Thrombosis remains a prime reason of mortality worldwide. With the available antithrombotic drugs, bleeding remains the major downside of current treatments. This raises a clinical concern for all patients undergoing antithrombotic therapy.
Rohini Dwivedi, Vitor H. Pomin
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Fucoidan and Fucosylated Chondroitin Sulfate Stimulate Hematopoiesis in Cyclophosphamide-Induced Mice [PDF]
Marine Drugs, 2017 Application of cytostatics in cancer patients’ chemotherapy results in a number of side effects, including the inhibition of various parts of hematopoiesis.
Natalia Anisimova +6 more
doaj +3 more sources
Preparation and Characterization of <em>O</em>-Acylated Fucosylated Chondroitin Sulfate from Sea Cucumber [PDF]
Marine Drugs, 2012 Fucosylated chondroitin sulfate (FuCS), a kind of complex glycosaminoglycan from sea cucumber, has potent anticoagulant activity. In order to understand the relationship between structures and activity, the depolymerized FuCS (dFuCS) was chosen to ...
Na Gao +5 more
doaj +3 more sources
Marine DrugsFucosylated chondroitin sulfate is a unique glycosaminoglycan isolated from sea cucumbers, with excellent anticoagulant activity. The fucosyl branch in FCS is generally located at the 3-OH of D-glucuronic acid but, recently, a novel structure with α-L ...
Changlun Lv +4 more
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Semisynthetic Isomers of Fucosylated Chondroitin Sulfate Polysaccharides with Fucosyl Branches at a Non-Natural Site [PDF]
Biomacromolecules, 2021 The several interesting activities detected for fucosylated chondroitin sulfate (fCS) have fueled in the last years several efforts toward the obtainment of fCS oligosaccharides and low molecular weight (LMW) polysaccharides with a well-defined structure, in order to avoid the problems associated with the potential employment of native, sea cucumber ...
Vessella, Giulia +7 more
openaire +3 more sources
Marine Drugs, 2022 Glycosaminoglycan from Apostichopus japonicus (AHG) and its depolymerized fragments (DAHGs) are anticoagulant fucosylated chondroitin sulfate. The aim of this study was to further evaluate the anticoagulant and antithrombic activity of AHG and DAHGs, as ...
Han Wang +7 more
doaj +1 more source
Pharmaceuticals, 2023 Two fucosylated chondroitin sulfates were isolated from the sea cucumbers Psolus peronii and Holothuria nobilis using a conventional extraction procedure in the presence of papain, followed by anion-exchange chromatography on DEAE-Sephacel.
Nadezhda E. Ustyuzhanina +12 more
doaj +1 more source