Results 91 to 100 of about 14,436 (200)

Synthetic Retinoid Sulfarotene Selectively Inhibits Tumor‐Repopulating Cells of Intrahepatic Cholangiocarcinoma via Disrupting Cytoskeleton by P‐Selectin/PSGL1 N‐Glycosylation Blockage

Advanced Science
Intrahepatic cholangiocarcinoma (ICC) is a highly lethal malignancy that currently lacks effective clinical treatments. Eliminating stem cell‐like cancer cells is an extremely promising but challenging strategy for treating ICC.
Xiaojing Du, Zhuoran Qi, Sinuo Chen, Jinlan Wu, Ye Xu, Sunkuan Hu, Zhijie Yu, Jiayun Hou, Yuan Fang, Jinglin Xia, Xin Cao   +10 more
doaj   +1 more source

Core Fucosylation of Maternal Milk N-Glycan Evokes B Cell Activation by Selectively Promoting the l-Fucose Metabolism of Gut Bifidobacterium spp. and Lactobacillus spp

mBio, 2019
The maternal milk glycobiome is crucial for shaping the gut microbiota of infants. Although high core fucosylation catalyzed by fucosyltransferase 8 (Fut8) is a general feature of human milk glycoproteins, its role in the formation of a healthy ...
Ming Li, Yaqiang Bai, Jiaorui Zhou, Wei Huang, Jingyu Yan, Jia Tao, Qingjie Fan, Yang Liu, Di Mei, Qiulong Yan, Jieli Yuan, Patrice Malard, Zhongfu Wang, Jianguo Gu, Naoyuki Tanigchi, Wenzhe Li   +15 more
doaj   +1 more source

Carcinoma-associated fucosylated antigens are markers of the epithelial state and can contribute to cell adhesion through CLEC17A (Prolectin) [PDF]

, 2016
International audienceTerminal fucosylated motifs of glycoproteins and glycolipid chains are often altered in cancer cells. We investigated the link between fucosylation changes and critical steps in cancer progression: epithelial-to-mesenchymal ...
Altare, F, Barille-Nion, S, Bernardeau, K, Breiman, A, Drickamer, K, Echasserieau, K, Imberty, A, Le Pendu, J, Robles, MDL, Trecesson, SDC   +9 more
core   +5 more sources

Non-Secretor Status Due to FUT2 Stop Mutation Is Associated with Reduced Rotavirus Infections but Not with Other Enteric Pathogens in Rwandan Children

Microorganisms
Enteric pathogens remain a health threat for children in low-income countries. A single nucleotide polymorphism (SNP) in the FUT2 gene that precludes the expression of fucosyltransferase 2 has been reported to influence the susceptibility to rotavirus ...
Jean Bosco Munyemana, Jean Claude Kabayiza, Eric Seruyange, Staffan Nilsson, Gustaf E. Rydell, Anna Martner, Maria E. Andersson, Magnus Lindh   +7 more
doaj   +1 more source

Biochemical characterization of Helicobacter pylori α-1,4 fucosyltransferase: metal ion requirement, donor substrate specificity and organic solvent stability [PDF]

, 2018
The effect of metal ions on the activity, the donor substrate specificity, and the stability in organic solvents of Helicobacter pylori α-1,4 fucosyltransferase were studied. The recombinant enzyme was expressed as soluble form in E.
Corona, Francesco, Ernst, Beat, Rabbani, Said   +2 more
core  

Profiling the host defense responses against Candida auris in a reliable Drosophila melanogaster infection model

mLife, Volume 5, Issue 1, Page 51-67, February 2026.
Abstract The “superbug” Candida auris has been ranked as a priority fungal pathogen and is becoming a serious threat to public health. However, the underlying mechanisms of real‐world pathogen–host interactions remain elusive, in part due to the lack of powerful immunocompetent animal models.
Jie Li, Guangsheng Chen, Xiangkang Zeng, Jiaxin Lin, Xiaoqing Chen, Wenqiang Wang, Yueru Tian, Xinhua Huang, Yun Zou, Ming Guan, Zhiyi He, Hailei Wang, Changbin Chen, Lei Pan   +13 more
wiley   +1 more source

Human fucosyltransferase 6 enables prostate cancer metastasis to bone [PDF]

, 2014
Background: The interaction between human prostate cancer (PCa) cells and bone marrow (BM) endothelium follows a rolling-and-adhesion cascade mediated by E-selectin ligand (ESL): E-selectin.
Barthel, S R, Dimitroff, C J, Guillebon, A D, Hsu, J-w, King, M R, Lee, Y-F, Li, J   +6 more
core   +1 more source

Human Milk Bioactive Compounds and Allergic‐ and Infectious‐Related Infant Outcomes: A Systematic Review

Molecular Nutrition &Food Research, Volume 70, Issue 4, 26 February 2026.
Human milk bioactive compounds influence infant immune development by reducing infection risk and modulating allergy‐related outcomes. This systematic review highlights associations between HMOs, fatty acids, cytokines, and protective or adverse immune responses in early life.
Eduard Flores Ventura, Daria Guseva, Vanessa Hübert, Anna Samarra, Regina Ensenauer, Maria Carmen Collado   +5 more
wiley   +1 more source

C-Terminal Truncation of α 1,6-Fucosyltransferase from Rhizobium Sp. does not Annul the Transferase Activity of the Enzyme [PDF]

, 2002
6 pages.-- PMID: 11814863 [PubMed].Recently we have over-expressed the enzyme a 1,6-fucosyltransferase from Rhizobium sp. in Escherichia coli. In this heterologous system the enzyme was mainly expressed as inclusion bodies and the one that was expressed ...
Bastida, Agatha, Fernández-Mayoralas, Alfonso, García-Junceda, Eduardo   +2 more
core   +2 more sources

Comparative whole genome re-sequencing analysis in upland New Rice for Africa: insights into the breeding history and respective genome compositions

Rice, 2018
Background Increasing rice demand is one of the consequences of the steadily improving socio-economic status of the African countries. New Rice for Africa (NERICA), which are interspecific hybrids between Asian and African rice varieties, are one of ...
Naoki Yamamoto, Richard Garcia, Tomohiro Suzuki, Celymar Angela Solis, Yuichi Tada, Ramaiah Venuprasad, Ajay Kohli   +6 more
doaj   +1 more source