Results 101 to 110 of about 14,436 (200)

Transcriptomic analysis of Ascaris suum larvae during their hepatopulmonary migration [PDF]

, 2012
Common roundworms are important intestinal nematodes of man (Ascaris lumbricoides) and pig (Ascaris suum). During the first stages of the infection, the larvae of these parasites undergo a hepatopulmonary migration.
Gasser, Robin, Geldhof, Peter, Jex, Aaron, Vlaminck, Johnny, Wang, Tao   +4 more
core   +1 more source

FUT8 promotes breast cancer cell invasiveness by remodeling TGF-β receptor core fucosylation

Breast Cancer Research, 2017
Background Core fucosylation (addition of fucose in α-1,6-linkage to core N-acetylglucosamine of N-glycans) catalyzed by fucosyltransferase 8 (FUT8) is critical for signaling receptors involved in many physiological and pathological processes such as ...
Cheng-Fen Tu, Meng-Ying Wu, Yuh-Charn Lin, Reiji Kannagi, Ruey-Bing Yang   +4 more
doaj   +1 more source

RNA-Seq analysis of glycosylation related gene expression in STZ-induced diabetic rat kidney inner medulla

Frontiers in Physiology, 2015
The UT-A1 urea transporter is crucial to the kidney’s ability to generate concentrated urine. Native UT-A1 from kidney inner medulla (IM) is a heavily glycosylated protein with two glycosylation forms of 97 and 117 kDa.
Xiaoqian eQian, Xuechen eLi, Titilayo O Ilori, Janet D. Klein, Rebecca P Hughey, Cong-jun eLi, Abdel A Alli, Zhengyu eGuo, Peng eYu, Xiang eSong, Guangping eChen   +10 more
doaj   +1 more source

Functional properties, structural studies and chemoenzymatic synthesis of oligosaccharides [PDF]

Oligosaccharides offer beneficial effects on immune system and gut health, such as anticancer activity, immunomodulatory activity, and complement activation. Functional oligosaccharides are widely found in plants, algae, bacteria and higher fungi.
Cao, H, Liu, B, Liu, X, Nahar, L, Sarker, SD, Wu, Y, Yu, H, Zhao, C   +7 more
core   +1 more source

Diagnostic, prognostic, and immunological roles of FUT8 in lung adenocarcinoma and lung squamous cell carcinoma.

PLoS ONE
Lung cancer remains the leading cause of malignant tumors worldwide in terms of the incidence and mortality, posing a significant threat to human health.
Zhijun Li, Zhenpeng Zhu, Peng Wang, Chenyang Hou, Lijuan Ren, Dandan Xu, Xiran Wang, Fei Guo, Qingxue Meng, Weizheng Liang, Jun Xue, Xuejun Zhi   +11 more
doaj   +1 more source

Genome-wide association study identifies _FUT8_ and _ESR2_ as co-regulators of a bi-antennary N-linked glycan A2 (GlcNAc~2~Man~3~GlcNAc~2~) in human plasma proteins [PDF]

, 2009
HPLC analysis of N-glycans quantified levels of the biantennary glycan (A2) in plasma proteins of 924 individuals. Subsequent genome-wide association study (GWAS) using 317,503 single nucleotide polymorphysms (SNP) identified two genetic loci influencing
Alan F. Wright, Ana Knezevic, Caroline Hayward, Gordan Lauc, Harry Campbell, Igor Rudan, Ivana Kolcic, Jennifer Huffman, Lina Zgaga, Nicholas D. Hastie, Olga Gornik, Ozren Polasek, Pauline M. Rudd, Veronique Vitart, Zrinka Biloglav   +14 more
core   +1 more source

Molecular cloning and functional expression of a novel Helicobacter pylori α-1,4 fucosyltransferase [PDF]

, 2017
Helicobacter pylori is an important human pathogen which causes both gastric and duodenal ulcers and is associated with gastric cancer and lymphoma. This microorganism synthesizes fucosylated oligosaccharides, predominantly the Galb-1,4GlcNAc (Type II ...
Ernst, Beat, Miksa, Viktoria, Rabbani, Said, Wipf, Beat   +3 more
core  

FUT6 Suppresses the Proliferation, Migration, Invasion, and Epithelial–Mesenchymal Transition of Esophageal Carcinoma Cells via the Epidermal Growth Factor Receptor/Extracellular Signal-Regulated Kinase Signaling Pathway

The Turkish Journal of Gastroenterology
Background/Aims: Esophageal cancer (ESCA) is a high-incidence disease worldwide, of which the 5-year survival rate remains dismal since the cellular basis of ESCA remains largely unclear.
Jianle Lao, Yanmin Pang, Hongming Chen, Xiqiang Tang, Rizhu Li, Danlei Tong, Ping Qiu, Qianli Tang   +7 more
doaj   +1 more source

α1,3Fucosyltransferase VI is expressed in HepG2 cells and codistributed with β1,4galactosyltransferase I in the Golgi apparatus and monensin-induced swollen vesicles [PDF]

, 2017
The major α1,3fucosyltransferase activity in plasma, liver, and kidney is related to fucosyltransferase VI which is encoded by the FUT6 gene. Here we demonstrate the presence of α1,3fucosyltransferase VI (α3-FucT VI) in the human HepG2 hepatoma cell line
Berger, Eric G., Borsig, Lubor, Höchli, Matthias, Imbach, Timo   +3 more
core  

Stronger inflammatory/cytotoxic T cell response in women identified by microarray analysis [PDF]

, 2008
Women develop chronic inflammatory autoimmune diseases like lupus more often than men. The mechanisms causing the increased susceptibility are incompletely understood, although estrogen is believed to contribute.
Anura Hewagama, Bruce C. Richardson, Dipak Patel, Faith M. Strickland, Sushma Yarlagadda   +4 more
core   +1 more source