Results 51 to 60 of about 48,475 (224)

Multiple‐point magnetic resonance acoustic radiation force imaging

Magnetic Resonance in Medicine, Volume 81, Issue 2, Page 1104-1117, February 2019., 2019
Abstract Purpose To implement and evaluate an efficient multiple‐point MR acoustic radiation force imaging pulse sequence that can volumetrically measure tissue displacement and evaluate tissue stiffness using focused ultrasound (FUS) radiation force. Methods Bipolar motion‐encoding gradients were added to a gradient‐recalled echo segmented EPI pulse ...
Henrik Odéen, Joshua de Bever, Lorne W. Hofstetter, Dennis L. Parker   +3 more
wiley   +1 more source

The FUS(s) about splicing [PDF]

, 2014
Fused in sarcoma (FUS), also called translocated in liposarcoma (TLS), is a ubiquitously expressed DNA/RNA binding protein belonging to the TET family and predominantly localized in the nucleus.
Ruepp, Marc-David
core  

Number of differentially expressed genes by mutant FUS, FUS overexpression, and FUS knock-down. [PDF]

, 2013
Number of differentially expressed genes by mutant FUS, FUS overexpression, and FUS knock-down.
John E. Landers (172264), Marka van Blitterswijk (119410), Ashley Lyn Leclerc (400572), Eric T. Wang (256097), Pamela J. Keagle (400570), Jan H. Veldink (119438), David E. Housman (254310), Brad A. Friedman (400569), Leonard H. van den Berg (119440), Patrick Lowe (400571)   +9 more
core   +1 more source

FUS and Prostate [PDF]

, 2020
In this study, we evaluated FUS expression in non-neoplastic tissue and prostatic adenocarcinoma, the association between FUS expression and clinical/laboratory progression, and the ability of FUS expression to predict Gleason scores >6 in Gleason ...
HIRTH, C (via Mendeley Data)
core   +1 more source

Mesenchymal stem cell–derived extracellular vesicle treatment of induced pluripotent stem cell–derived motor neurons with different amyotrophic lateral sclerosis genetic backgrounds

Neural Regeneration Research
Motor neurons derived from induced human pluripotent stem cells offer a powerful model to study motor neuron diseases, such as amyotrophic lateral sclerosis. While widely used, our knowledge of the proteomic changes in these models is rather rudimentary.
Suzy Varderidou-Minasian, Channa E. Jakobs, Svetlana Pasteuning-Vuhman, Lars Gal, Annabel Timmers, Maarten Altelaar, Magdalena J. Lorenowicz, R. Jeroen Pasterkamp   +7 more
doaj   +1 more source

Protein arginine methyltransferase 1 and 8 interact with FUS to modify its sub-cellular distribution and toxicity in vitro and in vivo. [PDF]

PLoS ONE, 2013
Amyotrophic lateral sclerosis (ALS) is a late onset and progressive motor neuron disease. Mutations in the gene coding for fused in sarcoma/translocated in liposarcoma (FUS) are responsible for some cases of both familial and sporadic forms of ALS.
Chiara Scaramuzzino, John Monaghan, Carmelo Milioto, Nicholas A Lanson, Astha Maltare, Tanya Aggarwal, Ian Casci, Frank O Fackelmayer, Maria Pennuto, Udai Bhan Pandey   +9 more
doaj   +1 more source

Prematurely Aged Human Microglia Exhibit Impaired Stress Response and Defective Nucleocytoplasmic Shuttling of ALS Associated FUS

Aging Cell, Volume 24, Issue 11, November 2025.
We developed a human microglia aging model by doxycycline‐induced GFP‐progerin expression, which offers a valuable tool to study human microglial aging and its contribution to neurodegeneration. Induced HMC3‐Progerin cells exhibited increased age markers as well as transcriptomic alterations, including an age‐associated transcriptomic shift and ...
Christiane Hartmann, Christina Haß, Muriel Knobloch, Israel Barrantes, Laura Fumagalli, Jessie Premereur, Franz Markert, Maite Peters, Georgia Koromila, Alexander Hartmann, Kathrin Jäger, Jette Abel, Renzo Mancuso, Alexander Storch, Michael Walter, Georg Fuellen, Andreas Hermann   +16 more
wiley   +1 more source

The ALS/FTLD‐related RNA‐binding proteins TDP‐43 and FUS have common downstream RNA targets in cortical neurons

FEBS Open Bio, Volume 4, Issue 1, Page 1-10, January 01, 2014., 2014
TDP‐43 and FUS are linked to amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD), and loss of function of either protein contributes to these neurodegenerative conditions. To elucidate the TDP‐43‐ and FUS‐regulated pathophysiological RNA metabolism cascades, we assessed the differential gene expression and alternative ...
Daiyu Honda, Shinsuke Ishigaki, Yohei Iguchi, Yusuke Fujioka, Tsuyoshi Udagawa, Akio Masuda, Kinji Ohno, Masahisa Katsuno, Gen Sobue   +8 more
wiley   +1 more source

Validity and Reliability of the Fundamental Motor Skills in Sports (FUS) Test for Iranian Children and Adolescents [PDF]

International Journal of School Health
Background: Confident and proficient participation in physical activities throughout life relies on mastering Fundamental Motor Skills. Given the need for more effective solutions in assessing fundamental basic skills in both children and adolescents ...
Mohammad Hossein Zamani, Ayoub Hashemi, Elahe Siavashi, Razieh Khanmohamadi, Hamideh Saeidi   +4 more
doaj   +1 more source

Conformational change of RNA-helicase DHX30 by ALS/FTD-linked FUS induces mitochondrial dysfunction and cytosolic aggregates

Scientific Reports, 2022
Genetic mutations in fused in sarcoma (FUS) cause amyotrophic lateral sclerosis (ALS). Although mitochondrial dysfunction and stress granule have been crucially implicated in FUS proteinopathy, the molecular basis remains unclear.
Ryota Hikiami, Toshifumi Morimura, Takashi Ayaki, Tomoyuki Tsukiyama, Naoko Morimura, Makiko Kusui, Hideki Wada, Sumio Minamiyama, Akemi Shodai, Megumi Asada-Utsugi, Shin-ichi Muramatsu, Takatoshi Ueki, Ryosuke Takahashi, Makoto Urushitani   +13 more
doaj   +1 more source