Results 31 to 40 of about 1,288,108 (273)

The beginning and the end of SNARE‐induced membrane fusion

FEBS Open Bio, 2022
Membrane fusion is not a spontaneous process. Physiologically, the formation of coiled‐coil protein complexes, the SNAREpins, bridges the membrane of a vesicle and a target membrane, brings them in close contact, and provides the energy necessary for ...
Delphine Mion, Louis Bunel, Paul Heo, Frédéric Pincet   +3 more
doaj   +1 more source

Vesicle Shrinking and Enlargement Play Opposing Roles in the Release of Exocytotic Contents

Cell Reports, 2020
Summary: For decades, two fusion modes were thought to control hormone and transmitter release essential to life; one facilitates release via fusion pore dilation and flattening (full collapse), and the other limits release by closing a narrow fusion ...
Wonchul Shin, Gianvito Arpino, Sathish Thiyagarajan, Rui Su, Lihao Ge, Zachary McDargh, Xiaoli Guo, Lisi Wei, Oleg Shupliakov, Albert Jin, Ben O’Shaughnessy, Ling-Gang Wu   +11 more
doaj   +1 more source

Fusion proteins and fusion pores [PDF]

The EMBO Reports, 2000
Sponsored by the Juan March Foundation and organized by R D Burgoyne and G Alvarez de Toledo, Madrid, Spain, May 22–24, 2000. ![][1] A meeting was recently held at the Juan March Foundation in Madrid (22–24 May, 2000) on the topic ‘Regulated exocytosis and the vesicle cycle’.
R D, Burgoyne, G, Alvarez de Toledo
openaire   +2 more sources

Differential cargo mobilisation within Weibel-Palade bodies after transient fusion with the plasma membrane. [PDF]

, 2014
Inflammatory chemokines can be selectively released from Weibel-Palade bodies (WPBs) during kiss-and-run exocytosis. Such selectivity may arise from molecular size filtering by the fusion pore, however differential intra-WPB cargo re-mobilisation ...
Knipe, Laura, Tom Carter (196826), Carter, T, Laura Knipe (196817), Hannah, MJ, Kiskin, Nikolai I, Kiskin, NI, Nikolai I Kiskin, Matthew J. Hannah (196824), Matthew J Hannah, Babich, Victor, Nikolai I. Kiskin (631240), Victor Babich, Knipe, L, Tom Carter, Victor Babich (631241), Laura Knipe, Carter, Tom, Babich, V, Hannah, Matthew J   +19 more
core   +1 more source

The structure of Herpesvirus Fusion Glycoprotein B-Bilayer Complex reveals the protein-membrane and lateral protein-protein interaction [PDF]

, 2013
Glycoprotein B (gB) is a key component of the complex herpesvirus fusion machinery. We studied membrane interaction of two gB ectodomain forms and present an electron cryotomography structure of the gB-bilayer complex.
Topf, Maya, Huiskonen, JT, Topf, M., Maurer, U., Whitbeck, J., Maurer, U.E., Gruenewald, Kay, Cohen, G., Cairns, T.M., Eisenberg, R.J., Huiskonen, Juha T., Whitbeck, J.C., Zeev-Ben-Mordehai, T, Cohen, Gary H., Cohen, GH, Cairns, Tina M., Hannah, BP, Hannah, B.P., Cohen, G.H., Pandurangan, A., Zeev-Ben-Mordehai, T., Grünewald, K, Eisenberg, Roselyn J., Cairns, T., Huiskonen, J.T., Maurer, Ulrike E., Grünewald, Kay, Eisenberg, RJ, Topf, M, Grünewald, K., Maurer, UE, Pandurangan, Arun Prasad, Whitbeck, JC, Zeev-Ben-Mordehai, Tzviya, Huiskonen, J., Hannah, Brian P., Hannah, B., Pandurangan, Arun, Pandurangan, AP, Eisenberg, R., Whitbeck, J. Charles, Cairns, TM   +41 more
core   +2 more sources

Ketamine Alters Functional Plasticity of Astroglia: An Implication for Antidepressant Effect

Life, 2021
Ketamine, a non-competitive N–methyl–d–aspartate receptor (NMDAR) antagonist, exerts a rapid, potent and long-lasting antidepressant effect, although the cellular and molecular mechanisms of this action are yet to be clarified.
Matjaž Stenovec
doaj   +1 more source

NDC1 : a crucial membrane-integral nucleoporin of metazoan nuclear pore complexes [PDF]

, 2006
POM121 and gp210 were, until this point, the only known membrane-integral nucleoporins (Nups) of vertebrates and, thus, the only candidate anchors for nuclear pore complexes (NPCs) within the nuclear membrane. In an accompanying study (Stavru et al.), we
Gorlich, D., Hülsmann, Bastian, Anne Spang, Cordes, V., Stavru, F., Hartmann, E., Dirk Görlich, Spang, Anne, Cordes, Volker, C., Volker C. Cordes, Hülsmann, B., Hulsmann, B. B., Bastian B. Hülsmann, Cordes, V. C., Hartmann, Enno, Fabrizia Stavru, Görlich, Dirk, Stavru, Fabrizia, Enno Hartmann, Spang, A., Cordes, Volker,   +20 more
core   +1 more source

Filling Potholes on the Path to Fusion Pores [PDF]

Biophysical Journal, 2002
Membrane fusion is at the heart of eukaryotic cell life. Carefully regulated membrane fusion is required for cell compartmentalization, for the import of large molecules into the cell, and for the export both of waste molecules and of signaling molecules that carry information to other cells in a community.
Lentz, Barry R., Siegel, David P., Malinin, Vladimir   +2 more
openaire   +2 more sources

Yield stress fluids method to determine the pore size distribution of a porous medium [PDF]

, 2014
In this paper a new method is presented in order to determine the pore size distribution in a porous medium. This original technique uses the rheological properties of some non-Newtonian yield stress fluids flowing through the porous sample.
AMBARI, Abdelhak, CHAMPMARTIN, Stephane, OUKHLEF, Aimad   +2 more
core   +1 more source

Impedance analysis and single ion channel recordings on pore-suspending lipid bilayers based on highly ordered pore arrays [PDF]

, 2006
Ion channels are one of the main drug targets and are in the focus of various membrane biosensor applications and drug screening assays. The aim of this thesis was to develop and characterize a novel membrane system suspending highly ordered porous ...
Römer, Winfried
core   +1 more source