Results 41 to 50 of about 1,288,108 (273)
The fusion pores of Ca2+-triggered exocytosis [PDF]
Nature Structural & Molecular Biology, 2008 The aqueous compartment inside a vesicle makes its first connection with the extracellular fluid through an intermediate structure termed the exocytotic fusion pore. Progress in exocytosis can be measured in terms of the formation and growth of the fusion pore.
Meyer B, Jackson, Edwin R, Chapman
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Single-channel electrophysiology reveals a distinct and uniform pore complex formed by α-synuclein oligomers in lipid membranes. [PDF]
, 2012 Synucleinopathies such as Parkinson's disease, multiple system atrophy and dementia with Lewy bodies are characterized by deposition of aggregated α-synuclein.
Felix Schmidt +11 more
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Vesicular control of fusion pore expansion. [PDF]
Commun Integr Biol, 2015 Exocytic post-fusion events play an important role determining the composition and quantity of cellular secretion. In particular, Ca(2+)-dependent regulation of fusion pore dilation/closure is a key regulator for fine-tuning vesicle content secretion. This requires a tight temporal and spatial integration of vesicle fusion with the PM, Ca(2+) signals ...
Neuland K, Frick M.
europepmc +3 more sources
Colorimetry in Nuclear Fusion Research
, 2022 0000-0001-5522-3082Colorimetry is a unique technique among research fields. The technique is also utilized in nuclear fusion research. The motivation is to evaluate the wide range of distribution of the deposition layer on the surface of the vacuum ...
MOTOJIMA, Gen, 66700
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Acta Biologica Slovenica, 2009 Vesicles are cellular organelles, in which signaling molecules (neurotransmitters or hormones) are stored and are essential for the function of neurons and endocrine cells in supporting the communication between tissues and organs.
Nina Vardjan +4 more
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In search of the fusion pore of exocytosis [PDF]
Biophysical Chemistry, 2007 Research on calcium-triggered exocytosis has converged on the fusion pore as a critical kinetic intermediate. Using sensitive biophysical methods to record signals from living cells in the act of releasing neurotransmitter or hormone has provided clues about the structure and composition of fusion pores.
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Toward a unified picture of the exocytotic fusion pore. [PDF]
FEBS Lett, 2018 Neurotransmitter and hormone release involve calcium‐triggered fusion of a cargo‐loaded vesicle with the plasma membrane. The initial connection between the fusing membranes, called the fusion pore, can evolve in various ways, including rapid dilation to allow full cargo release, slow expansion, repeated opening–closing and resealing.
Karatekin E.
europepmc +4 more sources
SNARE-Mediated Exocytosis in Neuronal Development
Frontiers in Molecular Neuroscience, 2020 The formation of the nervous system involves establishing complex networks of synaptic connections between proper partners. This developmental undertaking requires the rapid expansion of the plasma membrane surface area as neurons grow and polarize ...
Fabio L. Urbina +4 more
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v-SNARE transmembrane domains function as catalysts for vesicle fusion
eLife, 2016 Vesicle fusion is mediated by an assembly of SNARE proteins between opposing membranes, but it is unknown whether transmembrane domains (TMDs) of SNARE proteins serve mechanistic functions that go beyond passive anchoring of the force-generating SNAREpin
Madhurima Dhara +10 more
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Medical image fusion: A survey of the state of the art [PDF]
, 2014 Medical image fusion is the process of registering and combining multiple images from single or multiple imaging modalities to improve the imaging quality and reduce randomness and redundancy in order to increase the clinical applicability of medical ...
James, Alex Pappachen +2 more
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