Fusion Pore Diameter Regulation by Cations Modulating Local Membrane Anisotropy
The Scientific World Journal, 2012 The fusion pore is an aqueous channel that is formed upon the fusion of the vesicle membrane with the plasma membrane. Once the pore is open, it may close again (transient fusion) or widen completely (full fusion) to permit vesicle cargo discharge. While
Doron Kabaso +5 more
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Calcium release through P2X4 activates calmodulin to promote endolysosomal membrane fusion [PDF]
, 2015 Intra-endolysosomal Ca(2+) release is required for endolysosomal membrane fusion with intracellular organelles. However, the molecular mechanisms for intra-endolysosomal Ca(2+) release and the downstream Ca(2+) targets involved in the fusion remain ...
Baars +70 more
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Impact of surface and pore characteristics on fatigue life of laser powder bed fusion Ti–6Al–4V alloy described by neural network models [PDF]
Scientific Reports, 2021 In this study, the effects of surface roughness and pore characteristics on fatigue lives of laser powder bed fusion (LPBF) Ti–6Al–4V parts were investigated.
Seunghyun Moon +9 more
semanticscholar +1 more source
Exo70-Mediated Recruitment of Nucleoporin Nup62 at the Leading Edge of Migrating Cells is Required for Cell Migration [PDF]
, 2009 Nucleoporin Nup62 localizes at the central channel of the nuclear pore complex and is essential for nucleocytoplasmic transport. Through its FG-repeat domain, Nup62 regulates nuclear pore permeability and binds nuclear transport receptors.
Bayliss +61 more
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Acta Biologica Slovenica, 2009 Vesicles are cellular organelles, in which signaling molecules (neurotransmitters or hormones) are stored and are essential for the function of neurons and endocrine cells in supporting the communication between tissues and organs.
Nina Vardjan +4 more
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Dynamin Is Functionally Coupled to Insulin Granule Exocytosis [PDF]
, 2007 The insulin granule integral membrane protein marker phogrin-green fluorescent protein was co-localized with insulin in Min6B1 beta-cell secretory granules but did not undergo plasma membrane translocation following glucose stimulation.
Gaisano, HY +7 more
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Criticality of porosity defects on the fatigue performance of wire + arc additive manufactured titanium alloy [PDF]
, 2019 This study was aimed at investigating the effect of internal porosity on the fatigue strength of wire + arc additive manufactured titanium alloy (WAAM Ti-6Al-4V).
Awd, Mustafa +6 more
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Commentary: Ion Channels, Fusion Pores and Exocytosis [PDF]
Journal of Molecular Neuroscience, 2012 No abstract ...
CARBONE, Emilio +3 more
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v-SNARE transmembrane domains function as catalysts for vesicle fusion
eLife, 2016 Vesicle fusion is mediated by an assembly of SNARE proteins between opposing membranes, but it is unknown whether transmembrane domains (TMDs) of SNARE proteins serve mechanistic functions that go beyond passive anchoring of the force-generating SNAREpin
Madhurima Dhara +10 more
doaj +1 more source
The exocytotic fusion pore modeled as a lipidic pore
Biophysical Journal, 1992 Freeze-fracture electron micrographs from degranulating cells show that the lumen of the secretory granule is connected to the extracellular compartment via large (20 to 150 nm diameter) aqueous pores. These exocytotic fusion pores appear to be made up of a highly curved bilayer that spans the plasma and granule membranes.
Nanavati, C. +3 more
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