Results 71 to 80 of about 1,811,201 (303)

Neuronal fusion pore assembly requires membrane cholesterol [PDF]

Cell Biology International, 2007
AbstractCholesterol has been proposed to play a critical role in regulating neurotransmitter release and synaptic plasticity. The neuronal porosome/fusion pore, the secretory machinery at the nerve terminal, is a 12–17 nm cup‐shaped lipoprotein structure composed of cholesterol and a number of proteins, among them calcium channels, and the t‐SNARE ...
Won Jin, Cho, Aleksandar, Jeremic, Huan, Jin, Gang, Ren, Bhanu P, Jena   +4 more
openaire   +2 more sources

New insights into the control of secretion

Communicative & Integrative Biology, 2009
Vesicular secretion is a fundamental process in the body with vesicle fusion releasing vesicle contents to the outside. This process, called exocytosis, is usually thought of as leading to an all-or-none release of content; regulation of secretory output
Peter Thorn
doaj   +1 more source

Novel Roles of the Nipah Virus Attachment Glycoprotein and Its Mobility in Early and Late Membrane Fusion Steps

mBio, 2022
The Paramyxoviridae family comprises important pathogens that include measles (MeV), mumps, parainfluenza, and the emerging deadly zoonotic Nipah virus (NiV) and Hendra virus (HeV).
Victoria Ortega, J. Lizbeth Reyes Zamora, I. Abrrey Monreal, Daniel T. Hoffman, Shahrzad Ezzatpour, Gunner P. Johnston, Erik M. Contreras, Fernando J. Vilchez-Delgado, Hector C. Aguilar   +8 more
doaj   +1 more source

Laser irradiated foam targets: absorption and radiative properties [PDF]

, 2018
An experimental campaign to characterize the laser radiation absorption of foam targets and the subsequent emission of radiation from the produced plasma was carried out in the ABC facility of the ENEA Research Center in Frascati (Rome).
Cipriani, Mattia, Consoli, Fabrizio, Cristofari, Giuseppe, De Angelis, Riccardo, di Giorgio, Giorgio, Giulietti, Danilo, Ingenito, Francesco, Luigi Andreoli, Pier, Rupasov, Alexander A., Salvadori, Martina, Yu. Gus’kov, Sergey   +10 more
core   +2 more sources

The fusion pores of Ca2+-triggered exocytosis [PDF]

Nature Structural & Molecular Biology, 2008
The aqueous compartment inside a vesicle makes its first connection with the extracellular fluid through an intermediate structure termed the exocytotic fusion pore. Progress in exocytosis can be measured in terms of the formation and growth of the fusion pore.
Meyer B, Jackson, Edwin R, Chapman
openaire   +2 more sources

CaMKIIalpha interacts with multi-PDZ domain protein MUPP1 in spermatozoa and prevents spontaneous acrosomal exocytosis [PDF]

, 2009
The success of acrosomal exocytosis, a complex process with a variety of inter-related steps, relies on the coordinated interaction of participating signaling molecules.
Ackermann, Frauke, Boekhoff, Ingrid, Borth, Heike, Buech, Thomas, Gudermann, Thomas, Zitranski, Nele   +5 more
core   +1 more source

SERINC5 protein inhibits HIV-1 fusion pore formation by promoting functional inactivation of envelope glycoproteins

Journal of Biological Chemistry, 2017
The host proteins, SERINC3 and SERINC5, have been recently shown to incorporate into HIV-1 particles and compromise their ability to fuse with target cells, an effect that is antagonized by the viral Nef protein.
Chetan Sood, M. Marin, A. Chande, M. Pizzato, G. Melikyan   +4 more
semanticscholar   +1 more source

TRIM67 regulates exocytic mode and neuronal morphogenesis via SNAP47

Cell Reports, 2021
Summary: Neuronal morphogenesis involves dramatic plasma membrane expansion, fueled by soluble N-ethylmaleimide-sensitive factor attachment protein eceptors (SNARE)-mediated exocytosis.
Fabio L. Urbina, Shalini Menon, Dennis Goldfarb, Reginald Edwards, M. Ben Major, Patrick Brennwald, Stephanie L. Gupton   +6 more
doaj   +1 more source

Comparison of unitary exocytic events in pituitary lactotrophs and in astrocytes: modelling the discrete open fusion-pore states

Frontiers in Cellular Neuroscience, 2013
In regulated exocytosis the merger between the vesicle and the plasma membranes leads to the formation of an aqueous channel (a fusion-pore), through which vesicular secretions exit into the extracellular space.
Doron eKabaso, Doron eKabaso, Jernej eJorgačevski, Jernej eJorgačevski, Ana Isabel Calejo, Ana Isabel Calejo, Ajda eFlasker, Alenka eGucek, Marko eKreft, Marko eKreft, Marko eKreft, Robert eZorec, Robert eZorec   +12 more
doaj   +1 more source

Fusion pore conductance to determine the effects of mutating the structure of influenza virus hemagglutinin [PDF]

, 2016
Enveloped viruses, such as influenza, infect cells by fusing their viral envelope with the cell membrane. The fusion pore is a macromolecular structure that links two membranes that are fusing.
Wachter, Rebecca
core   +1 more source