Results 61 to 70 of about 1,811,201 (303)
Dilation of fusion pores by crowding of SNARE proteins
eLife, 2017 Hormones and neurotransmitters are released through fluctuating exocytotic fusion pores that can flicker open and shut multiple times. Cargo release and vesicle recycling depend on the fate of the pore, which may reseal or dilate irreversibly.
Zhenyong Wu +7 more
doaj +1 more source
Nanoporous silica-based protocells at multiple scales for designs of life and nanomedicine. [PDF]
, 2015 Various protocell models have been constructed de novo with the bottom-up approach. Here we describe a silica-based protocell composed of a nanoporous amorphous silica core encapsulated within a lipid bilayer built by self-assembly that provides for ...
Brinker, C Jeffrey +3 more
core +2 more sources
Structure and Composition of the Fusion Pore [PDF]
Biophysical Journal, 2003 Earlier studies using atomic force microscopy (AFM) demonstrated the presence of fusion pores at the cell plasma membrane in a number of live secretory cells, revealing their morphology and dynamics at nm resolution and in real time. Fusion pores were stable structures at the cell plasma membrane where secretory vesicles dock and fuse to release ...
Jena, Bhanu P. +4 more
openaire +2 more sources
Dynamic rearrangement of nucleoporins during fungal "open" mitosis [PDF]
, 2008 Mitosis in animals starts with the disassembly of the nuclear pore complexes and the breakdown of the nuclear envelope. In contrast to many fungi, the corn smut fungus Ustilago maydis also removes the nuclear envelope.
Theisen, Ulrike +2 more
core +1 more source
SNARE-Mediated Exocytosis in Neuronal Development
Frontiers in Molecular Neuroscience, 2020 The formation of the nervous system involves establishing complex networks of synaptic connections between proper partners. This developmental undertaking requires the rapid expansion of the plasma membrane surface area as neurons grow and polarize ...
Fabio L. Urbina +4 more
doaj +1 more source
Regulation of mitochondrial permeability transition pore by PINK1 [PDF]
, 2012 Background: Loss-of-function mutations in PTEN-induced kinase 1 (PINK1) have been linked to familial Parkinson’s disease, but the underlying pathogenic mechanism remains unclear.
Caballero, Erica +7 more
core +3 more sources
Simulation and prediction of membrane fusion dynamics
Theoretical and Applied Mechanics Letters, 2022 Membrane fusion is an important process by which biological membranes perform their life activities. Simulations show that the membrane fusion process happens mainly through three pathways, where the Stalk-Pore hypothesis, in which two membranes come ...
Zhi Zheng, Shouqin Lü, Mian Long
doaj +1 more source
New mechanism of membrane fusion
, 2001 We have carried out Monte Carlo simulation of the fusion of bilayers of single chain amphiphiles which show phase behavior similar to that of biological lipids. The fusion mechanism we observe is very different from the ``stalk'' hypothesis.
K. Katsov +3 more
core +1 more source
Selective laser sintering of hydroxyapatite reinforced polyethylene composites for bioactive implants and tissue scaffold development [PDF]
, 2006 Selective laser sintering (SLS) has been investigated for the production of bioactive implants and tissue scaffolds using composites of high-density polyethylene (HDPE) reinforced with hydroxyapatite (HA) with the aim of achieving the rapid manufacturing
Berry E. +19 more
core +2 more sources
Mechanics of membrane fusion/pore formation
Chemistry and Physics of Lipids, 2015 Lipid bilayers play a fundamental role in many biological processes, and a considerable effort has been invested in understanding their behavior and the mechanism of topological changes like fusion and pore formation. Due to the time- and length-scale on which these processes occur, computational methods have proven to be an especially useful tool in ...
Fuhrmans, Marc +3 more
openaire +3 more sources