Results 81 to 90 of about 1,288,108 (273)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Design of Intense Neutron Source for Fusion Material Study and the Role of Universities [PDF]
, 1993 Need and requirement for the intense neutron source for fusion materials study have been discussed for many years. Recently, international climate has been becoming gradually maturing to consider this problem more seriously because of the recognition of ...
ISHINO, Shiori
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Visualization of expanding fusion pores in secretory cells [PDF]
Journal of General Physiology, 2018 Abbineni et al. examine recent imaging work on fusion pores and discuss the dynamics of PI-4,5-P2 accumulation on granule membranes.
Prabhodh S. Abbineni +2 more
openaire +2 more sources
Vesicular release of glutamate utilizes the proton gradient between the vesicle and synaptic cleft
Frontiers in Synaptic Neuroscience, 2010 Glutamate is released from synaptic vesicles following formation of a fusion pore, connecting the vesicle interior with the synaptic cleft. Release is proposed to result from either full fusion of the vesicle with the terminal membrane or by ‘kiss-
Jon T Brown +5 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Origin of Exocytotic Fusion Pore Dynamics [PDF]
, 2015 Vesicular membrane fusion involves the release of contents in a broad array of biological systems, such as intracellular trafficking, secretion, fertilization, and development.
Stratton, Benjamin Somerall
core +1 more source
Sub-quantal release is not dominant during prolonged depolarization in adrenal chromaffin cells
Biophysical ReportsExocytosis, which mediates important functions like synaptic transmission and stress responses, has been postulated to release all transmitter molecules in the vesicle in the “all-or-none” quantal hypothesis.
Lisi Wei +5 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2017 Upon cell stimulation, the network of cortical actin filaments is rearranged to facilitate the neurosecretory process. This actin rearrangement includes both disruption of the preexisting actin network and de novo actin polymerization.
Arlek M. González-Jamett +8 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Studies on D-3^He Fusion in LHD [PDF]
, 1996 In LHD ( Large Helical Device ) studies on realization of D-D fusion burning has been carried out, where tritium burning is out of this plan. We propose experiments on D-^3He fusion in this plan. This fueled fusion has the reaction cross-section as large
YAMAZAKI, Kozo +12 more
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