Results 11 to 20 of about 7,531,916 (333)

A transient increase of HIF-1α during the G1 phase (G1-HIF) ensures cell survival under nutritional stress [PDF]

Cell Death and Disease, 2023
The family of hypoxia-inducible transcription factors (HIF) is activated to adapt cells to low oxygen conditions, but is also known to regulate some biological processes under normoxic conditions.
Ratnal Belapurkar, Maximilian Pfisterer, Jan Dreute, Sebastian Werner, Sven Zukunft, Ingrid Fleming, Michael Kracht, M. Lienhard SCHMITZ   +7 more
doaj   +2 more sources

The length of the G1 phase is an essential determinant of H3K27me3 landscapes across diverse cell types. [PDF]

PLoS Biology
Stem cells have lower facultative heterochromatin as defined by trimethylation of histone H3 lysine 27 (H3K27me3) compared to differentiated cells. However, the mechanisms underlying these differential H3K27me3 levels remain elusive.
Abby Trouth, Kameswaran Ravichandran, Philip R Gafken, Sara Martire, Gabriel E Boyle, Giovana M B Veronezi, Van La, Stephanie J Namciu, Laura A Banaszynski, Jay F Sarthy, Srinivas Ramachandran   +10 more
doaj   +2 more sources

Invadopodia-mediated ECM degradation is enhanced in the G1 phase of the cell cycle.

J Cell Sci, 2019
The process of tumor cell invasion and metastasis includes assembly of invadopodia, protrusions capable of degrading the extracellular matrix (ECM). The effect of cell cycle progression on invadopodia has not been elucidated.
Bayarmagnai B, Perrin L, Esmaeili Pourfarhangi K, Graña X, Tüzel E, Gligorijevic B.   +5 more
europepmc   +2 more sources

G1/S transcription factors assemble in increasing numbers of discrete clusters through G1 phase. [PDF]

J Cell Biol, 2020
In budding yeast, the transcription factors SBF and MBF activate a large program of gene expression in late G1 phase that underlies commitment to cell division, termed Start. SBF/MBF are limiting with respect to target promoters in small G1 phase cells and accumulate as cells grow, raising the questions of how SBF/MBF are dynamically distributed across
Black L, Tollis S, Fu G, Fiche JB, Dorsey S, Cheng J, Ghazal G, Notley S, Crevier B, Bigness J, Nollmann M, Tyers M, Royer CA.   +12 more
europepmc   +4 more sources

G1 Phase Process [PDF]

Definitions, 2020

semanticscholar   +2 more sources

ZSTK474 targeting PIK3R3 inhibits the Wilms' tumor through G0 / G1 phase arrest. [PDF]

PLoS ONE
PurposeWilms' tumor (WT), also known as nephroblastoma, is the predominant form of primary malignant renal cancer. The unfavorable prognoses linked to anaplastic nephroblastoma and recurrent nephroblastoma emphasize the crucial requirement for the ...
Maoxian Li, Jiayan Liu, Liming Jin, Tao Mi, Zhaoxia Zhang, Chenghao Zhanghuang, Mujie Li, Jinkui Wang, Xin Wu, Zhaoying Wang, Zhang Wang, Dawei He   +11 more
doaj   +2 more sources

Negative Regulation of G1 Phase [PDF]

Definitions, 2020

semanticscholar   +2 more sources

G1-Phase [PDF]

Springer Reference Medizin, 2019
M. O'connell, N. Walworth
semanticscholar   +2 more sources

Timing of growth affected broiler breeder feeding motivation and reproductive traits

Poultry Science, 2021
: The amount and timing of growth are important factors that affect age at first egg, body conformation, reproductive performance, and hunger in broiler breeders.
Mohammad Afrouziyeh, Nicole M. Zukiwsky, Martin J. Zuidhof   +2 more
doaj   +1 more source

Atypical cell cycle profile of mouse embryonic stem cell is regulated by classic oncogenic and tumor suppressive genes in vitro

Heliyon, 2022
Embryonic stem cells (ESCs) exhibit an unusual cell cycle profile containing a short G1 phase. Whether this feature is required to maintain pluripotency is a matter of debate.
Jinfeng Jiang, Tong Qiu, Chao Yang, Yuan Yuan, Ling Qin, Peixuan Zhang   +5 more
doaj   +1 more source