Results 21 to 30 of about 7,531,916 (333)
The G1/S repressor WHI5 is expressed at similar levels throughout the cell cycle
BMC Research Notes, 2022 Objectives While it is clear that cells need to grow before committing to division at the G1/S transition of the cell cycle, how cells sense their growth rate or size at the molecular level is unknown.
Sylvain Tollis
doaj +1 more source
Genetics Research, 2023 The key event of liver regeneration initiation (LRI) is the switch of hepatocytes from the G0 phase to the G1 phase. This study aimed to use the data from large-scale quantitatively detecting and analyzing (LQDA) to reveal the regulation of hepatocytes ...
Xiayan Zang +9 more
doaj +1 more source
Critical Role for P53 in Regulating the Cell Cycle of Ground State Embryonic Stem Cells
Stem Cell Reports, 2020 Summary: Mouse embryonic stem cells (ESCs) grown in serum-supplemented conditions are characterized by an extremely short G1 phase due to the lack of G1-phase control. Concordantly, the G1-phase-specific P53-P21 pathway is compromised in serum ESCs. Here,
Menno ter Huurne +5 more
doaj +1 more source
Altered G1 phase regulation in osteosarcoma [PDF]
International Journal of Cancer, 1997 Alterations in the normal cell cycle lead to abnormal cell proliferation and to tumor development. To explore the role of the cyclin D/Cdk4 complex and the retinoblastoma protein (pRb) in the growth and spread of osteoblastic osteosarcoma (OS), 40 tumor samples were selected. In 17 of these cases, lung metastases occurred during follow-up.
M S, Benassi +10 more
openaire +2 more sources
Mitotic UV irradiation induces a DNA replication-licensing defect that potentiates G1 arrest response. [PDF]
PLoS ONE, 2015 Cdt1 begins to accumulate in M phase and has a key role in establishing replication licensing at the end of mitosis or in early G1 phase. Treatments that damage the DNA of cells, such as UV irradiation, induce Cdt1 degradation through PCNA-dependent CRL4-
Masayuki Morino +6 more
doaj +1 more source
G1 Phase Lengthening During Neural Tissue Development Involves CDC25B Induced G1 Heterogeneity [PDF]
SSRN Electronic Journal, 2020 ABSTRACTWhile lengthening of the cell cycle and G1 phase is a generic feature of tissue maturation during development, the underlying mechanism remains still poorly understood. Here we develop a time lapse imaging strategy to measure the four phases of the cell cycle in single neural progenitor cells in their endogenous environment.
Angie Molina +6 more
openaire +1 more source
Chromosome-condensed G1 phase yeast cells are tolerant to desiccation stress
Microbial Cell, 2021 The budding yeast Saccharomyces cerevisiae is capable of surviving extreme water loss for a long time. However, less is known about the mechanism of its desiccation tolerance.
Zhaojie Zhang, Gracie R. Zhang
doaj +1 more source
Influence of cell cycle phase on calcification in the coccolithophore Emiliania huxleyi [PDF]
, 2008 Calcification of the cosmopolitan coccolithophore species Emiliania huxleyi was investigated in relation to the cell division cycle with the use of batch cultures.
Antia, Avan +2 more
core +1 more source
Cell Reports, 2017 Summary: Cells initiate fate decisions during G1 phase by converting extracellular signals into distinctive cell cycle kinetics. The DNA replication timing is determined in G1 phase; lengthened G1 and hastened S phases correlate with increased neurogenic
Alison A. Lanctot +5 more
doaj +1 more source
The properties of nerve cell precursors in hydra [PDF]
, 1986 Two signals, the head activator and an injury stimulus, control differentiation of nerve cells from uncommitted stem cells in hydra [Th. Holstein, H. C. Schaller, and C. N. David, (1986) Dev. Biol. 115, 9–17].
David, Charles N., Holstein, Thomas W.
core +1 more source