Results 41 to 50 of about 7,531,916 (333)
Virus Research, 2018 Highlights • PEDV causes Vero cell cycle arrest in the G0/G1 phase.• PEDV through p53-dependent pathway causes cell cycle arrest in the G0/G1 phase.• Vero cells released from G0/G1 phase are advantageous for PEDV replication.• This is the first report ...
P. Sun +6 more
semanticscholar +1 more source
The Rad4TopBP1 ATR-Activation domain functions in G1/S phase in a chromatin-dependent manner [PDF]
, 2012 DNA damage checkpoint activation can be subdivided in two steps: initial activation and signal amplification. The events distinguishing these two phases and their genetic determinants remain obscure.
Carr, Antony +8 more
core +4 more sources
Expression of the NS5 (VPg) Protein of Murine Norovirus Induces a G1/S Phase Arrest. [PDF]
PLoS ONE, 2016 Murine norovirus-1 (MNV-1) is known to subvert host cell division inducing an accumulation of cells in the G0/G1 phase, creating conditions where viral replication is favored. This study identified that NS5 (VPg), is capable of inducing cell cycle arrest
Colin Davies, Vernon K Ward
doaj +1 more source
Constitutively high dNTP concentration inhibits cell cycle progression and the DNA damage checkpoint in yeast Saccharomyces cerevisiae [PDF]
, 2007 In eukaryotic cells the concentration of dNTP is highest in S phase and lowest in G1 phase and is controlled by ribonucleotide reductase (RNR). RNR activity is eliminated in all eukaryotes in G1 phase by a variety of mechanisms: transcriptional ...
A. Chabes +40 more
core +1 more source
Growth Peculiarities of the Saccharomyces cerevisiae Culture in the Presence of Exogenous Autoregulators of the Cell Population Density [PDF]
Учёные записки Казанского университета: Серия Естественные науки, 2015 A dose-dependent effect of budding suppression in yeasts, depending on their concentration (1.0, 10, and 100 μM) and the growth phase of the culture at the time of exposure to phenylethanol was observed during the study of growth peculiarities of the S ...
E.T. Kalimullina +3 more
doaj
Nature Communications, 2016 Embryonic stem cells (ESCs) represent a transient biological state, where pluripotency is coupled with fast proliferation. ESCs display a constitutively active DNA damage response (DDR), but its molecular determinants have remained elusive.
A. Ahuja +10 more
semanticscholar +1 more source
Cell Division, 2021 Background The budding yeast protein Chl1p is a nuclear protein required for sister-chromatid cohesion, transcriptional silencing, rDNA recombination, ageing and plays an instrumental role in chromatin remodeling.
Muhseena N. Katheeja +2 more
doaj +1 more source
Cell Cycle Control by Optogenetically Regulated Cell Cycle Inhibitor Protein p21
Biology, 2023 The progression through the cell cycle phases is driven by cyclin-dependent kinases and cyclins as their regulatory subunits. As nuclear protein, the cell cycle inhibitor p21/CDKN1A arrests the cell cycle at the growth phase G1 by inhibiting the activity
Levin Lataster +5 more
doaj +1 more source
Scientific Reports, 2016 Potent anti-cancer compounds FR901464 and its methyl-ketal derivative spliceostatin A (SSA) inhibit cell cycle progression at G1 and G2/M phases. These compounds bind to the spliceosome and inhibit the splicing reaction.
T. Satoh, D. Kaida
semanticscholar +1 more source
Cell-Cycle-Dependent Regulation of Ca2+-Activated K+ Channel in Jurkat T-Lymphocyte
Journal of Pharmacological Sciences, 2007 Small-conductance Ca2+-activated K+ (SK2) channel plays an important role in the activation of Jurkat T-lymphocytes by maintaining electrical gradients for the sustained Ca2+ influx. Apamin-sensitive K+ current was significantly decreased with cell-cycle
Takashi Morimoto +4 more
doaj +1 more source