Results 11 to 20 of about 16,477,249 (235)

G Protein-Coupled Estrogen Receptor: Rapid Effects on Hippocampal-Dependent Spatial Memory and Synaptic Plasticity

Frontiers in Endocrinology, 2020
In the hippocampus, estrogen regulates gene transcription linked to neuronal growth, neuroprotection, and the maintenance of memory function (1–3). The mechanism is likely to involve genomic regulation through classic estrogen receptor (ER) signaling ...
Ashok Kumar, Thomas C. Foster
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Decreased Levels of G Protein-Coupled Estrogen Receptor in Bipolar Patients

Genel Tıp Dergisi, 2023
Objectives: There is increasing evidence in the literature that estrogen and its receptors play an important role in the etiopathogenesis of bipolar disorder due to gender differences in the course, severity and peak periods of the disease.
Nurinnisa Öztürk, Onur Hurşitoğlu, Ömer Faruk Uygur, Ergul Belge Kurutas   +3 more
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Transactivation of G protein-coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs): Recent insights using luminescence and fluorescence technologies [PDF]

, 2021
© 2020 The Authors Alterations in signalling due to bidirectional transactivation of G protein-coupled receptor (GPCRs) and receptor tyrosine kinases (RTKs) are well established. Transactivation significantly diversifies signalling networks within a cell
Kilpatrick, Laura E., Hill, Stephen J.
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Evidence for G‐Protein–Coupled Estrogen Receptor as a Pronatriuretic Factor

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background The novel estrogen receptor, G‐protein–coupled estrogen receptor (GPER), is responsible for rapid estrogen signaling. GPER activation elicits cardiovascular and nephroprotective effects against salt‐induced complications, yet there is no ...
Eman Y. Gohar, Elizabeth M. Daugherty, Jeffrey O. Aceves, Randee Sedaka, Ijeoma E. Obi, J. Miller Allan, Reham H. Soliman, Chunhua Jin, Carmen De Miguel, Sarah H. Lindsey, Jennifer S. Pollock, David M. Pollock   +11 more
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G protein-coupled estrogen receptor in GtoPdb v.2023.1 [PDF]

, 2023
The G protein-coupled estrogen receptor (GPER, nomenclature as agreed by the NC-IUPHAR Subcommittee on the G protein-coupled estrogen receptor [26]) was identified following observations of estrogen-evoked cyclic AMP signalling in breast cancer cells [2],
Edward J. Filardo, Eric R. Prossnitz, Prossnitz, Eric R., Filardo, Edward J.   +3 more
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G protein-coupled estrogen receptor in GtoPdb v.2021.3 [PDF]

, 2021
The G protein-coupled estrogen receptor (GPER, nomenclature as agreed by the NC-IUPHAR Subcommittee on the G protein-coupled estrogen receptor [25]) was identified following observations of estrogen-evoked cyclic AMP signalling in breast cancer cells [2],
Neubig, Richard, Prossnitz, Eric R., Filardo, Edward J.   +2 more
core   +1 more source

G protein-coupled estrogen receptor regulates embryonic heart rate in zebrafish. [PDF]

PLoS Genetics, 2017
Estrogens act by binding to estrogen receptors alpha and beta (ERα, ERβ), ligand-dependent transcription factors that play crucial roles in sex differentiation, tumor growth and cardiovascular physiology.
Shannon N Romano, Hailey E Edwards, Jaclyn Paige Souder, Kevin J Ryan, Xiangqin Cui, Daniel A Gorelick   +5 more
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Targeting the G protein-coupled estrogen receptor (GPER) in obesity and diabetes

Endocrine and Metabolic Science, 2021
Obesity has become a global epidemic in the modern world with the numbers of obese individuals having risen at alarming rates in the last decades. Obesity represents a serious medical condition that can lead to multiple complications, such as diabetes ...
Geetanjali Sharma, Eric R. Prossnitz
doaj   +1 more source

GPCR-OKB: the G protein coupled receptor oligomer knowledge base [PDF]

, 2010
Rapid expansion of available data about G Protein Coupled Receptor (GPCR) dimers/oligomers over the past few years requires an effective system to organize this information electronically.
Bas Vroling, Pin, J.-P., Palczewski, K., Camacho-Artacho, Marta, Pin, J.P., Lucy Skrabanek, Jean-Philippe Pin, Marta Camacho-Artacho, Devi, Lakshmi A, Graeme Milligan, Marta Filizola, Campagne, Fabien, Fabien Campagne, Martin J. Lohse, Jufang Shan, Lohse, Martin J, Vriend, Gerrit, Khelashvili, George, Milligan, Graeme, Camacho-Artacho, M., Skrabanek, L., George Khelashvili, Campagne, F., Susan R. George, Lakshmi A. Devi, Filizola, M., Pin, Jean-Philippe, Vroling, B., Bouvier, M., Devi, L.A., Richard R. Neubig, Marc Parmentier, George, Susan R, Palczewski, Krzysztof, Dorff, K., Shan, J., Vriend, G., Michel Bouvier, Lohse, M.J., Bouvier, Michel, Skrabanek, Lucy, Vroling, Bas, Filizola, Marta, Neubig, Richard R, Gerrit Vriend, Dorff, Kevin, Parmentier, Marc, Khelashvili, G., Javitch, J.A., Shan, Jufang, Parmentier, M., Javitch, Jonathan A, Krzysztof Palczewski, Kevin Dorff, Jonathan A. Javitch, George, S.R., Neubig, R.R., Milligan, G.   +57 more
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Role of estrogen receptors in health and disease

Frontiers in Endocrinology, 2022
Estrogen receptors (ERs) regulate multiple complex physiological processes in humans. Abnormal ER signaling may result in various disorders, including reproductive system-related disorders (endometriosis, and breast, ovarian, and prostate cancer), bone ...
Peng Chen, Bo Li, Ling Ou-Yang
doaj   +1 more source